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Immunomics of Immune Rejection

2008
There is overwhelming evidence that the innate and adaptive arms of the human immune system can interact with autologous tumor cells and can, in rare circumstances, clear the host of cancer. Yet, most often tumor cells strike a favorable balance with the host’s immune response and continue their proliferation.
Ena Wang   +2 more
openaire   +1 more source

Corneal Allograft Rejection Following Immunization

American Journal of Ophthalmology, 1988
Five patients developed corneal allograft rejection after immunization. One patient, a 33-year-old woman, received a tetanus toxoid booster nine months after a corneal transplant for keratoconus. Within four days she developed a graft rejection that required a penetrating keratoplasty two years later.
T L, Steinemann   +2 more
openaire   +2 more sources

Immunity and graft rejection in the ear

Immunology Today, 1984
Immunological activity in the ear and nose is often overlooked but can cause disease. Some examples were discussed at a recent conference*. Also considered was one of the most successful applications of tissue transplantation, middle ear reconstruction.
openaire   +2 more sources

Fetal rejection: infertility and immunity

Expert Review of Clinical Immunology, 2007
Defective reaction toward fetal alloantigens could result in both recurrent spontaneous abortions (RSAs) and recurrent early pregnancy failures (REPFs), the latter existing in couples with unexplained infertility and multiple failures of implantation after in vitro fertilization embryo transfer.
openaire   +2 more sources

Electrochemical Modification of Hyperacute Immune Rejection

European Surgical Research, 2008
A heterotopic liver experiment was set up in which a force field was applied to the transplanted liver. By whatever technique the field was applied it modified the rejection of the liver in a fashion predicted by measurement and an outline of the equipotential lines of force generated by the applied electric field.
P N, Sawyer   +6 more
openaire   +2 more sources

Immune landscape of the kidney allograft in response to rejection

Clinical Science, 2023
Abstract Preventing kidney graft dysfunction and rejection is a critical step in addressing the nationwide organ shortage and improving patient outcomes. While kidney transplants (KT) are performed more frequently, the overall number of patients on the waitlist consistently exceeds organ availability. Despite improved short-term outcomes
Harsimar Kaur Ahuja   +3 more
openaire   +2 more sources

Immune Tolerance and Rejection in Organ Transplantation

2019
In this chapter, we describe the history of transplantation, the multiple cell types, and mechanisms that are involved in rejection and tolerance of a transplanted organ, as well as summarize the common and promising new therapeutics used in transplant patients.
Jessica, Stolp   +2 more
openaire   +2 more sources

Idiotypic immunization induces immunity to mutated p53 and tumor rejection

Nature Medicine, 1998
The p53 molecule might serve as a common tumor-associated antigen, as the tumor suppressor gene p53 is mutated and the p53 protein is often over-expressed in tumor cells. We report that effective immunity to p53 can be induced through an idiotypic network by immunization of mice with a monoclonal antibody (PAb-240) specific for mutated p53, or with a ...
P J, Ruiz   +11 more
openaire   +2 more sources

Immunization-Associated Corneal Transplantation Rejection: A Review

Cornea, 2021
Purpose: The purpose of this review was to examine and characterize the available literature regarding immunization-associated corneal graft rejection. Methods: A Literature search was conducted using PubMed keywords relevant to corneal transplantation, graft rejection, and ...
Edward H, Lee, Jennifer Y, Li
openaire   +2 more sources

Uric Acid Promotes Tumor Immune Rejection

Cancer Research, 2004
Abstract Uric acid released from dying cells has been shown recently to act as a danger signal for the immune system, stimulating dendritic cell maturation and enhancing T-cell responses to foreign antigens. Stimulation of dendritic cell maturation by uric acid has been proposed as a mechanism by which the immune system could generate ...
De-En, Hu   +3 more
openaire   +2 more sources

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