Results 71 to 80 of about 292,750 (306)

Biofabrication of Endothelialized, Intrinsically Vascularized 3D‐Printed Recombinant Spider Silk Scaffolds

Advanced Healthcare Materials, EarlyView.
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold, Stefanie Heltmann‐Meyer, Xuen J. Ng, Thomas Scheibel, Tobias Fey, Harald Wajant, Carol Geppert, Andreas Arkudas, Dominik Steiner, Raymund E. Horch   +9 more
wiley   +1 more source

Immunobiology of solid cancers: cellular and molecular pathways as potential diagnostic and therapeutic targets [PDF]

, 2018
In the last four decades, tumor immunology has shed light on identity and functions of cells and molecules involved in tumor rejection through the involvement of the immune system [1].
Braicu, E. I., Gasparri, M. L., Ruscito, I., Zizzari, I. G.   +3 more
core   +3 more sources

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation

Frontiers in Immunology
BackgroundImmune rejection represents a significant barrier to transplantation, especially in the context of xenotransplantation. Endothelial cells (ECs) derived from pigs serve as the initial barrier against the human immune system in ...
Weilong Li, Fang Yang, Dexin Yang, Zhuoheng Song, Zigan Xu, Jinmei Wu, Yanmei Li, Zixi Chen, Peishan Chen, Yeye Yu, Ting Xie, Cuishan Yang, Liying Zhou, Shaodong Luan, Hanchao Gao   +14 more
doaj   +1 more source

Immune status of recipients following bone marrow - Augmented solid organ transplantation [PDF]

, 1995
It has been postulated that the resident “passenger” leukocytes of hematolymphoid origin that migrate from whole organ grafts and subsequently establish systemic chimerism are essential for graft acceptance and the induction of donor-specific ...
Banas, R, Carroll, P, Demetris, J, Dodson, F, Fontes, P, Fung, JJ, Lombardozzi, S, Pappo, O, Pavlick, M, Pham, S, Rao, AS, Shapiro, R, Starzl, TE, Trucco, M, Zeevi, A   +14 more
core   +1 more source

Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]

, 2020
Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P., Leuvenink, Henri G. D., Nieuwenhuijs-Moeke, Gertrude J., Pischke, Soren E., Ploeg, Rutger J., Pol, Robert A., Sanders, Jan Stephan F., Struys, Michel   +7 more
core   +2 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Liver transplantation [PDF]

, 2014
Purpose of review: Long-term survival of liver transplant recipients is threatened by increased rates of de-novo malignancy and recurrence of hepatocellular carcinoma (HCC), both events tightly related to immunosuppression.
Burroughs, AK, De la Mata, M, Rodríguez-Perálvarez, M   +2 more
core  

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

Advanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal, Majd Bisharat, Bassma Khamaisi, Krishanu Ghosal, Eid Nassar‐Marjiya, Qi Wu, Shadi Daoud, Idan Redenski, Samer Srouji, Shady Farah   +9 more
wiley   +1 more source

Hypoimmunogenic Human iPSCs for Repair and Regeneration in the CNS

Cells
Human induced pluripotent stem cells (iPSCs) can be genetically engineered to evade host immune recognition, rendering them hypoimmunogenic and suitable as “universal donor” cells for allogeneic transplantation.
Haiwei Zhang, Hongxia Zhou, Xugang Xia, Qilin Cao, Ying Liu   +4 more
doaj   +1 more source