Results 101 to 110 of about 288,801 (335)

Utility of serological markers in inflammatory bowel diseases: Gadget or magic? [PDF]

open access: yes, 2007
The panel of serologic markers for inflammatory bowel diseases (IBD) is rapidly expanding. Although anti-Saccharomyces cerevisiae antibodies (ASCA) and atypical perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) remain the most widely ...
Altorjay, István   +3 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Screening of Anti HLA Class One Antibodies in the Sera of Pregnant Women and the Variation of Its Titer During Pregnancy

open access: yesپزشکی بالینی ابن سینا, 2001
Determination of HLA antigens has an extensive application in paternity,    Histocompatibility testing, and disease suseptibility identification. A vast    arrey of different HLA antisera are required for HLA typing. Such antisera can    be obtained from
Minoo Adib, Mina Adib
doaj  

SARS CoV subunit vaccine: Antibodymediated neutralisation and enhancement [PDF]

open access: yes, 2012
1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpike) and efficient establishment of a vaccination procedure in rodents. 2.
Altmeyer, R   +14 more
core   +1 more source

Characterization, cloning and immunogenicity of antigens released by transforming cercariae of Schistosoma mansoni [PDF]

open access: yes, 2000
A schistosome infection is initiated when the parasite penetrates the skin of a susceptible host. Relatively large quantities of protein are released by transforming cercariae compared to later larval stages.
Coulson, P.S.   +4 more
core   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Passive immunization against Histomonas meleagridis does not protect turkeys from an experimental infection [PDF]

open access: yes, 2009
Histomonosis or blackhead is a disease of gallinaceous birds, caused by the protozoan Histomonas meleagridis. As recent regulatory action has removed almost all drugs against this disease from the European market, the development of new prophylactics has
Bleyen, Nele   +3 more
core   +3 more sources

AN ELECTROPHORETIC STUDY OF IMMUNE SERA AND PURIFIED ANTIBODY PREPARATIONS [PDF]

open access: yesJournal of Experimental Medicine, 1939
1. Antibody produced in the horse migrates as a new serum component between the ß and γ components, whereas rabbit antibody is electrophoretically identical with the γ globulin component of the serum. 2. In rabbit and monkey antisera the percentage of antibody in the serum and in the γ globulin fraction can be determined by integration ...
Arne Tiselius, Elvin A. Kabat
openaire   +3 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

DIFFERENTIAL CROSS-NEUTRALIZATION OF DENGUE IMMUNE SERA AGAINST ZIKA VIRUS

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: Zika virus (ZIKV) is transmitted to humans primarily via the bites of infected female Aedes aegypti and Aedes albopictus. The mosquitoes are also the vector for the transmission of dengue viruses. Malaysia is a dengue hyperendemic country. To date,
J.-Y. Tan, K.-K. Tan, S. AbuBakar
doaj  

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