Results 171 to 180 of about 138,032 (344)
Is Platelet Desialylation a Novel Biomarker and Therapeutic Target in Immune Thrombocytopenia? [PDF]
, 2019 June Li, Jade A. Sullivan, Heyu Ni
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ChemistryOpen, EarlyView.Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar +8 more
wiley +1 more source
Mullins' syndrome: a new gammopathy-related autoinflammatory syndrome resistant to anakinra [PDF]
, 2015 A.L. Manson +12 more
core +1 more source
Chronic immune thrombocytopenia in sarcoidosis.
, 1990 Michie Hisada +5 more
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Expression and Significance of Regulatory B Cells in Patients with Immune Thrombocytopenia
, 2022 Wei Qian, Xiaoxia Zhang
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Pediatric Investigation, EarlyView.Tocilizumab combined with high‐dose methylprednisolone improved outcomes in children with acute necrotizing encephalopathy. A dose of 30 mg/(kg·day) may be more effective than 20 mg/(kg·day). ABSTRACT Importance Acute necrotizing encephalopathy (ANE) is a rare but life‐threatening pediatric neurological disorder characterized by rapid progression and ...
Fei Li +4 more
wiley +1 more source