Results 171 to 180 of about 1,871,257 (334)

Imbalanced immune homeostasis in immune thrombocytopenia [PDF]

Seminars in Hematology, 2016
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder resulting from low platelet counts caused by inadequate production as well as increased destruction by autoimmune mechanisms. As with other autoimmune disorders, chronic ITP is characterized by perturbations of immune homeostasis with hyperactivated effector cells as well as defective ...
openaire   +2 more sources

Leuprorelin‐Induced Thrombocytopenia Successfully Treated With Surgical Resection of the Injection Site

IJU Case Reports, EarlyView.
ABSTRACT Introduction Drug‐induced thrombocytopenia (DITP) can be caused by many kinds of drugs. Its treatment generally involves discontinuation of the responsible drug. Case Presentation A 70‐year‐old man received a subcutaneous injection of long‐acting (24‐week) leuprorelin depot as androgen deprivation therapy for prostate cancer.
Ryota Mori, Satoru Taguchi, Masahiro Yamamoto, Yuta Inoue, Koichiro Kanazawa, Yoichi Fujii, Haesu Lee, Kiichi Furuse, Hiroaki Maki, Jun Kamei, Shigenori Kakutani, Yuta Yamada, Aya Niimi, Daisuke Yamada, Aya Shinozaki‐Ushiku, Tetsuo Ushiku, Mineo Kurokawa, Mutsumi Okazaki, Haruki Kume   +18 more
wiley   +1 more source

Canine platelets express functional Toll-like receptor-4: lipopolysaccharide-triggered platelet activation is dependent on adenosine diphosphate and thromboxane A2 in dogs. [PDF]

, 2019
BackgroundFunctional Toll-like receptor 4 (TLR4) has been characterized in human and murine platelets indicating that platelets play a role in inflammation and hemostasis during sepsis. It is unclear whether canine platelets could express functional TLR4
Li, Ronald HL, Nguyen, Nghi, Tablin, Fern   +2 more
core   +1 more source

Immune-mediated thrombocytopenia of malaria. [PDF]

, 1983
John G. Kelton, Jay Keystone, J Moore, Gregory A. Denomme, Elaine Tozman, M. F. X. Glynn, P. B. Neame, Jack Gauldie, James B. Jensen   +8 more
openalex   +1 more source

Two‐Stage Tumor Resection for Locally Advanced Renal Cell Carcinoma With Level IV Tumor Thrombus and Pulmonary Embolism: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction We report a case of renal cell carcinoma with an inferior vena cava tumor thrombus extending into the right atrium and pulmonary embolism, treated using a staged surgical approach. Case Presentation A man in his 60s was diagnosed with left clear cell renal cell carcinoma with a tumor thrombus extending to the right atrium, posing ...
Takanari Kambe, Kei Mizuno, Yuki Teramoto, Takayuki Sumiyoshi, Yuki Kita, Kimihiko Masui, Takayuki Goto, Shusuke Akamatsu, Ryoichi Saito, Takashi Kobayashi   +9 more
wiley   +1 more source

Macrophage modulation in activation process induced immune thrombocytopenia

Universa Medicina
The immune system operates like an orchestra that harmoniously maintains the homeostasis balance while protecting from external or internal pathogens attack.
Mahdaleny Mahdaleny, Arleni Bustami, Febriana Catur Iswanti   +2 more
doaj   +1 more source

Secondary immune thrombocytopenic purpura with renal cell carcinoma

IJU Case Reports, 2019
Introduction Several types of cancers are reported to induce secondary immune thrombocytopenia resembling immune thrombocytopenic purpura‐like syndrome. However, renal cell carcinoma‐induced immune thrombocytopenic purpura is an extremely rare phenomenon.
Shigeaki Nakazawa, Masataka Kawamura, Kosuke Nakano, Norichika Ueda, Hidefumi Kishikawa, Hirokazu Kashiwagi, Motohide Uemura, Ryoichi Imamura, Kenji Nishimura, Norio Nonomura   +9 more
doaj   +1 more source

Monocyte-platelet interaction in immune and nonimmune thrombocytopenia [PDF]

, 1989
MN Saleh, DL Moore, JY Lee, AF LoBuglio
openalex   +1 more source

A Case of Hemophagocytic Lymphohistiocytosis During Immune Checkpoint Inhibitor Treatment for Metastatic Renal Cell Carcinoma, Complicated by Pancytopenia Attributed to Cytomegalovirus Infection

IJU Case Reports, EarlyView.
ABSTRACT Introduction Hemophagocytic lymphohistiocytosis (HLH) is characterized by macrophage and cytotoxic lymphocyte hyperactivation, fever, pancytopenia, liver dysfunction, and abnormal coagulation. However, no specific treatments have been established for HLH caused by immune checkpoint inhibitors.
Tomoko Honda, Hirohito Naito, Yu Osaki, Yoichiro Tohi, Yuki Matsuoka, Takuma Kato, Homare Okazoe, Rikiya Taoka, Nobufumi Ueda, Mikio Sugimoto   +9 more
wiley   +1 more source

Microarray Analysis of PBMC after Plasmodium falciparum Infection: Molecular Insights into Disease Pathogenesis [PDF]

, 2011
Our laboratory’s previous microarray analysis of subjects with Plasmodium falciparum revealed up-regulation of Toll-like receptor, NF-kB, TNF-α, IFN-γ, IL-1β, p38 MAPK, and MHC molecules.
Alan Scott, Anne Jedlicka, August Louis Bourgeois, Nathan Wolfe, Sher Singh, Wan-Chung(Wan-Jiung) Hu   +5 more
core   +1 more source