Results 21 to 30 of about 2,852,359 (355)
Placenta-Derived Exosomes as a Modulator in Maternal Immune Tolerance During Pregnancy
Frontiers in Immunology, 2021 Exosomes are a subset of extracellular vesicles with an average diameter of ~100nm. Exosomes are released by all cells through an endosome-dependent pathway and carry nucleic acids, proteins, lipids, cytokines and metabolites, mirroring the state of the ...
Kunfen Bai +6 more
semanticscholar +1 more source
HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance
Frontiers in Immunology, 2021 Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a mother can accept a genetically distinct fetus without immunological aggressive behavior.
Baimei Zhuang, Jin Shang, Yuanqing Yao
semanticscholar +1 more source
Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity
Cellular & Molecular Immunology, 2021 In addition to susceptibility to infections, conventional primary immunodeficiency disorders (PIDs) and inborn errors of immunity (IEI) can cause immune dysregulation, manifesting as lymphoproliferative and/or autoimmune disease.
G. Sogkas +5 more
semanticscholar +1 more source
Advances in Human Immune System Mouse Models for Personalized Treg-Based Immunotherapies
Frontiers in Immunology, 2021 Immunodeficient mice engrafted with a functional human immune system [Human immune system (HIS) mice] have paved the way to major advances for personalized medicine and translation of immune-based therapies.
Isabelle Serr +8 more
doaj +1 more source
Frontiers in Immunology, 2021 Transforming growth factor-β (TGF-β) is composed of three isoforms, TGF-β1, TGF-β2, and TGF-β3. TGF-β1 is a cytokine with multiple biological functions that has been studied extensively.
Dongyong Yang +10 more
semanticscholar +1 more source
Blood, 2021 New treatment options are required for patients with refractory immune thrombocytopenia (ITP), a disease in which immune tolerance has been lost due to reduced regulatory T-cell (Treg) activity.
P. Han +15 more
semanticscholar +1 more source
Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer [PDF]
, 2014 Copyright: © 2014 Li, Symonds, Miao, Sanderson and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Abraham +55 more
core +5 more sources
Challenges and Opportunities for Biomarkers of Clinical Response to AHSCT in Autoimmunity
Frontiers in Immunology, 2018 Autoimmunity represents a broad category of diseases that involve a variety of organ targets and distinct autoantigens. For patients with autoimmune diseases who fail to respond to approved disease-modifying treatments, autologous hematopoietic stem cell
Kristina M. Harris +4 more
doaj +1 more source
Immunotronics - novel finite-state-machine architectures with built-in self-test using self-nonself differentiation [PDF]
, 2002 A novel approach to hardware fault tolerance is demonstrated that takes inspiration from the human immune system as a method of fault detection. The human immune system is a remarkable system of interacting cells and organs that protect the body from ...
Bradley, D.W., Tyrrell, A.M.
core +2 more sources
The Immune Tolerance Role of the HMGB1-RAGE Axis
Cells, 2021 The disruption of the immune tolerance induces autoimmunity such as systemic lupus erythematosus and vasculitis. A chromatin-binding non-histone protein, high mobility group box 1 (HMGB1), is released from the nucleus to the extracellular milieu in ...
Haruki Watanabe, Myoungsun Son
semanticscholar +1 more source