Results 21 to 30 of about 1,132 (124)

Matrix metalloproteinase 7 is associated with symptomatic lesions and adverse events in patients with carotid atherosclerosis. [PDF]

PLoS ONE, 2014
BACKGROUND: Atherosclerosis is a major cause of cerebrovascular disease. Matrix metalloproteinases (MMPs) play an important role in matrix degradation within the atherosclerotic lesion leading to plaque destabilization and ischemic stroke.
Azhar Abbas, Pål Aukrust, David Russell, Kirsten Krohg-Sørensen, Trine Almås, Dorte Bundgaard, Vigdis Bjerkeli, Ellen Lund Sagen, Annika E Michelsen, Tuva B Dahl, Sverre Holm, Thor Ueland, Mona Skjelland, Bente Halvorsen   +13 more
doaj   +1 more source

Expression of hypoxia‐inducible factor 1α, glucose transporter 1, and hexokinase 2 in primary central nervous system lymphoma and the correlation with the biological behaviors

Brain and Behavior, Volume 10, Issue 8, August 2020., 2020
There was a hypoxic microenvironment, and HIF‐1α was involved in the regulation of glycolysis pathway in PCNSL. GLUT1 might be a potential marker for shorter PFS in PCNSL. Abstract Background It has been indicated that abnormal glucose metabolism mediated by hypoxia‐inducible factor 1α (HIF‐1α) played an essential role in the development of solid tumor.
Na Shen, Yaming Wang, Xuefei Sun, Xueyan Bai, Jinglan He, Qu Cui, Jun Qian, Hong Zhu, Yuedan Chen, Ruixian Xing, Qing Liu, Yuchen Wu, Junhong Li, Wenyuan Lai, Shengjun Sun, Nan Ji, Yuanbo Liu   +16 more
wiley   +1 more source

Masters of communication: The brain of the banded cleaner shrimp Stenopus hispidus (Olivier, 1811) with an emphasis on sensory processing areas

Journal of Comparative Neurology, Volume 528, Issue 9, Page 1561-1587, June 15, 2020., 2020
Cleaner shrimps feature a broad communicative repertoire which is considered to depend on superb motor skills and the underlying mechanosensory circuits in combination with sensory organs such as the two pairs of antennules and antennae, which are used both for attracting client fish and for intraspecific communication.
Jakob Krieger, Marie K. Hörnig, Renate E. Sandeman, David C. Sandeman, Steffen Harzsch   +4 more
wiley   +1 more source

Lymphomatoid contact dermatitis associated with textile dye at an unusual location

Indian Dermatology Online Journal, 2015
Lymphomatoid contact dermatitis (LCD) is a rare variant of noneczematous allergic contact dermatitis, which can mimick parapsoriasis or early-stage mycosis fungoides with its atypical clinical and histopathological manifestation.
Tuğba Kevser Uzunçakmak, Necmettin Akdeniz, Seyma Özkanlı, Zafer Türkoğlu, Ebru Itır Zemheri, Ayşe Serap Karadağ   +5 more
doaj   +1 more source

Multiparametric MRI enables for differentiation of different degrees of malignancy in two murine models of breast cancer

Frontiers in Oncology, 2022
ObjectiveThe objective of this study was to non-invasively differentiate the degree of malignancy in two murine breast cancer models based on identification of distinct tissue characteristics in a metastatic and non-metastatic tumor model using a ...
Mirjam Gerwing, Mirjam Gerwing, Emily Hoffmann, Emily Hoffmann, Katharina Kronenberg, Uwe Hansen, Max Masthoff, Max Masthoff, Anne Helfen, Anne Helfen, Christiane Geyer, Christiane Geyer, Lydia Wachsmuth, Lydia Wachsmuth, Carsten Höltke, Carsten Höltke, Bastian Maus, Bastian Maus, Verena Hoerr, Verena Hoerr, Verena Hoerr, Tobias Krähling, Tobias Krähling, Lena Hiddeßen, Walter Heindel, Walter Heindel, Uwe Karst, Melanie A. Kimm, Regina Schinner, Michel Eisenblätter, Michel Eisenblätter, Michel Eisenblätter, Cornelius Faber, Cornelius Faber, Moritz Wildgruber, Moritz Wildgruber, Moritz Wildgruber   +36 more
doaj   +1 more source

Clinical Profile and Treatment Outcomes of Metastatic Carcinoma with Unknown Primary: A Single Institution Experience

Asian Pacific Journal of Cancer Care, 2022
Background: Cancer of unknown primary origin (CUP) is a heterogeneous group of cancers defined by the presence of metastatic disease with no identified primary. CUP has been reported to comprise approximately 2% to 5% of all cancer cases.
Tavseef Ahmad Tali, Fiza Amin, Nazir Ahmad Khan, Javaid Ahmad Dar, Arshad Manzoor Najmi, Mushtaq Ahmad Sofi, Shahid Rashid, Waseem Aijaz Kitab, Murtaza Shaf, Mansoora Akhter   +9 more
doaj   +1 more source

Evaluation of lymphatic vessel dilatations by anterior segment swept-source optical coherence tomography: case report

BMC Ophthalmology, 2017
Background Conjunctival lymphangiectasia is a rare condition presumably caused by the obstruction of lymphatic channels or by an abnormal connection between conjunctival lymphatic and blood vessels. Diagnosis is based on clinical appearance and histology.
Eva Volek, Jeannette Toth, Zoltan Zsolt Nagy, Miklos Schneider   +3 more
doaj   +1 more source

Altered Expression Pattern of Topoisomerase IIα, in Ovarian Tumor Epithelial and Stromal Cells after Platinum-Based Chemotherapy

Neoplasia: An International Journal for Oncology Research, 2006
OBJECTIVE: The aim of this study was to evaluate the expression of topoisomerase IIα (TOP2A) in epithelial and stromal cells of ovarian cancer. METHODS: TOP2A expression was analyzed in normal ovarian tissue and in laser-microdissected ovarian tumor ...
Radoslav Chekerov, Irina Klaman, Menelaos Zafrakas, Dominique Könsgen, Alexander Mustea, Beate Petschke, Werner Lichtenegger, Jalid Sehouli, Edgar Dahl   +8 more
doaj   +1 more source

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

Advanced Science, Volume 12, Issue 36, September 25, 2025.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han, Dongliang Leng, Tuo Zhang, Jian Ge, Yinshan Fang, Tiankun Lu, Xue Dong, Manoj S Nair, Neranjan de Silva, Zhaowei Han, Tiancheng Jiao, Yuanhao Huang, Meiqi Zhao, Anjali Saqi, Hanina Hibshoosh, Zihe Meng, Jenny Z Xiang, Chendong Pan, Yanjie Sun, David D. Ho, Todd Evans, Jie Liu, Liuliu Yang, Jianwen Que, Shuibing Chen   +24 more
wiley   +1 more source

Value of Cell Block in the Diagnosis of Malignant Pleural Effusion

Chinese Journal of Lung Cancer, 2015
Malignant pleural effusion (MPE ) is due tumor which arises from the mesothelium or metastases from tumor origniating other sites. In large, for undiagnosed unilateral pleural effusions, the most frequent and important diagnosis to be established or ...
Fangyuan CHENG, Qian WANG, Diansheng ZHONG   +2 more
doaj   +1 more source