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Resource Bounded Immunity and Simplicity [PDF]
(journal version) Theoretical Computer Sceince, Vol.347,
pp.90-129, 2005, 2004 Revisiting the thirty years-old notions of resource-bounded immunity and simplicity, we investigate the structural characteristics of various immunity notions: strong immunity, almost immunity, and hyperimmunity as well as their corresponding simplicity notions.
Suzuki, Toshio, Yamakami, Tomoyuki
arxiv +7 more sources
Mathematical models for vaccination, waning immunity and immune system boosting: a general framework [PDF]
arXiv, 2015 When the body gets infected by a pathogen or receives a vaccine dose, the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery/vaccination the host might become susceptible again. Exposure to the pathogen in the environment boosts the immune system thus prolonging the duration of the protection ...
Barbarossa, Maria Vittoria +1 more
arxiv +5 more sources
Infection-acquired versus vaccine-acquired immunity in an SIRWS model [PDF]
arXiv, 2017 Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity. In some disease systems, the process of waning immunity can be non-linear, involving a complex relationship between the duration of immunity and subsequent boosting of immunity through ...
Campbell, Patricia T +4 more
arxiv +5 more sources
Defining trained immunity and its role in health and disease
Nature Reviews Immunology, 2020 Immune memory is a defining feature of the acquired immune system, but activation of the innate immune system can also result in enhanced responsiveness to subsequent triggers.
Mihai G Netea +2 more
exaly +2 more sources
Elements of cancer immunity and the cancer–immune set point
Nature, 2017 Daniel S Chen, Ira Mellman
exaly +2 more sources
Abstracts from the 2nd Annual MI4 Scientific Symposium on December 4, 2020
McGill Journal of Medicine, 2021 N ...
McGill Interdisciplinary Initiative in Infection and Immunity (MI4)
doaj +1 more source
Communications Medicine, 2021 Wurzel et al. describe the kinetics of the immune response in relation to clinical and virological features in a 5-month old infant with congenital heart disease and severe COVID-19.
Danielle Wurzel +30 more
doaj +1 more source
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint
Nature Communications, 2021 Shared metabolic pathways could allow simultaneous manipulation of T cells, viruses and tumours. Here the authors show targeting cholesterol esterification restrains hepatitis B in vitro, whilst bolstering exhausted antigen-specific T cell responses from
Nathalie M. Schmidt +20 more
doaj +1 more source
Nature Communications, 2023 A gB/MF59 vaccine candidate for human cytomegalovirus (HCMV) provided partial protection in organ transplant patients. Here, the authors identify antibody responses in trial participants that target virally infected cells to control cell-to-cell spread ...
A. C. Gomes +10 more
doaj +1 more source
Comparison of antibody responses to SARS-CoV-2 variants in Australian children
Nature Communications, 2022 Despite a rise in COVID-19 cases among children, there is limited understanding of the antibody responses mounted, compared to in adults. In this work, authors compare seroconversion rates and antibody responses in unvaccinated Australian children across
Zheng Quan Toh +12 more
doaj +1 more source