Results 1 to 10 of about 4,212,705 (397)
Defining trained immunity and its role in health and disease
Nature Reviews Immunology, 2020 Immune memory is a defining feature of the acquired immune system, but activation of the innate immune system can also result in enhanced responsiveness to subsequent triggers.
Mihai G Netea +2 more
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Elements of cancer immunity and the cancer–immune set point
Nature, 2017 Daniel S Chen, Ira Mellman
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Abstracts from the 2nd Annual MI4 Scientific Symposium on December 4, 2020
McGill Journal of Medicine, 2021 N ...
McGill Interdisciplinary Initiative in Infection and Immunity (MI4)
doaj +1 more source
Communications Medicine, 2021 Wurzel et al. describe the kinetics of the immune response in relation to clinical and virological features in a 5-month old infant with congenital heart disease and severe COVID-19.
Danielle Wurzel +30 more
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Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint
Nature Communications, 2021 Shared metabolic pathways could allow simultaneous manipulation of T cells, viruses and tumours. Here the authors show targeting cholesterol esterification restrains hepatitis B in vitro, whilst bolstering exhausted antigen-specific T cell responses from
Nathalie M. Schmidt +20 more
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Nature Communications, 2023 A gB/MF59 vaccine candidate for human cytomegalovirus (HCMV) provided partial protection in organ transplant patients. Here, the authors identify antibody responses in trial participants that target virally infected cells to control cell-to-cell spread ...
A. C. Gomes +10 more
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Comparison of antibody responses to SARS-CoV-2 variants in Australian children
Nature Communications, 2022 Despite a rise in COVID-19 cases among children, there is limited understanding of the antibody responses mounted, compared to in adults. In this work, authors compare seroconversion rates and antibody responses in unvaccinated Australian children across
Zheng Quan Toh +12 more
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Interaction between microbiota and immunity in health and disease
Cell Research, 2020 The interplay between the commensal microbiota and the mammalian immune system development and function includes multifold interactions in homeostasis and disease. The microbiome plays critical roles in the training and development of major components of
D. Zheng, T. Liwinski, E. Elinav
semanticscholar +1 more source
Biomedicines, 2022 Thyroid hormones have immunomodulatory roles, but their effects on the transcriptome and epigenome of innate immune cell types remain unexplored. In this study, we investigate the effects of triiodothyronine (T3) on the transcriptome and methylome of ...
Rebecca Shepherd +3 more
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The trinity of COVID-19: immunity, inflammation and intervention
Nature reviews. Immunology, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into the virology of SARS-CoV-2, understanding the fundamental physiological and ...
M. Tay +4 more
semanticscholar +1 more source