Results 61 to 70 of about 792,578 (312)
Attack and defence in cellular decision-making: lessons from machine learning [PDF]
Phys. Rev. X 9, 031012 (2019), 2018 Machine learning algorithms can be fooled by small well-designed adversarial perturbations. This is reminiscent of cellular decision-making where ligands (called antagonists) prevent correct signalling, like in early immune recognition. We draw a formal analogy between neural networks used in machine learning and models of cellular decision-making ...
arxiv +1 more source
Candida albicans colonization and dissemination from the murine gastrointestinal tract : the influence of morphology and Th17 immunity [PDF]
, 2014 This article is protected by copyright. All rights reserved. This work was supported by the Wellcome Trust (086558, 080088, 102705), a Wellcome Trust Strategic Award (097377) and a studentship from the University of Aberdeen. D.K.
Brown, Alistair J P +9 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Viruses, 2023 Cellular and humoral immunity are both required for SARS-CoV-2 infection recovery and vaccine efficacy. The factors affecting mRNA vaccination-induced immune responses, in healthy and fragile subjects, are still under investigation.
Giulia Brisotto +19 more
doaj +1 more source
A Guideline for the Statistical Analysis of Compositional Data in Immunology [PDF]
arXiv, 2022 The study of immune cellular composition has been of great scientific interest in immunology because of the generation of multiple large-scale data. From the statistical point of view, such immune cellular data should be treated as compositional. In compositional data, each element is positive, and all the elements sum to a constant, which can be set ...
arxiv
Error-prone cellular automata as metaphors of immunity as computation [PDF]
Complex Systems 24 (2015), 93-111, 2014 Modeling the immune system so that its essential functionalities stand out without the need for every molecular or cellular interaction to be taken into account has been challenging for many decades. Two competing approaches have been the clonal selection theory and the idiotypic-network theory, each stemming from a relatively separate set of ...
arxiv +1 more source
Hemispheric lateralisation and immune function: A systematic review of human research [PDF]
, 2011 This is the post-print version of the final paper published in Journal of Neuroimmunology. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Gidron, Y +4 more
core +2 more sources
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Pengaruh Asap Rokok Kretek Terhadap Imunitas Seluler Tikus Betina Strain Lmr [PDF]
, 2006 Experimental research was done to understand the effect of cigarette smoke to cellular immunity. In this research, 3 groups of rats were exposed by cigarette smoke for 7, 14, and 21 estrous cycles.
Hartamto, H. (Hadi), Idris, R. (Rosila)
core
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source