Results 71 to 80 of about 792,578 (312)
PTX3 is expressed in terminal lymphatics and shapes their organization and function
Frontiers in ImmunologyIntroductionThe lymphatic system is a multifaceted regulator of tissue homeostasis and an integral part of immune responses. Previous studies had shown that subsets of lymphatic endothelial cells (LEC) express PTX3, an essential component of humoral ...
Andrea Doni +18 more
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Investigations of cellular immunity in juvenile idiopathic arthritis
Central European Journal of Immunology, 2019 The following was emphasised in an informative, educational issued on the American College of Rheumatology website in April 2017: “About one child in every 1000 develops some type of chronic arthritis.
Lucia Maria Sur +3 more
doaj +1 more source
Current Status of Defensins and Their Role in Innate and Adaptive Immunity [PDF]
, 2002 Naturally occurring antimicrobial cationic polypeptides play a major role in innate and adaptive immunity. These polypeptides are found to be either linear and unstructured or structured through disulfide bonds.
Dentino, Andrew R., Raj, Periathamby A.
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, 2022 Background Cytochrome P450 4F3 (CYP4F3) is an ω‐hydroxylase that oxidizes leukotriene B4 (LTB4), prostaglandins, and fatty acid epoxides. LTB4 is synthesized by leukocytes and acts as a chemoattractant for neutrophils, making it an essential component of
Elien Smeets +18 more
doaj +1 more source
Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis. [PDF]
, 2014 Transition metal ions are essential micronutrients for all living organisms. In mammals, these ions are often protein-bound and sequestered within cells, limiting their availability to microbes. Moreover, in response to infection, mammalian hosts further
Diaz-Ochoa, Vladimir E +3 more
core +2 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Immune correlates of protection following Rift Valley fever virus vaccination
npj Vaccines, 2022 Rift Valley fever virus (RVFV) is a hemorrhagic fever virus with the potential for significant economic and public health impact. Vaccination with an attenuated strain, DelNSsRVFV, provides protection from an otherwise lethal RVFV challenge, but ...
Joshua D. Doyle +3 more
doaj +1 more source
Cellular Automata Simulation of Medication-Induced Autoimmune Diseases [PDF]
, 2003 We implement the cellular automata model proposed by Stauffer and Weisbuch in 1992 to describe the response of the immune system to antigens in the presence of medications. The model contains two thresholds, $\theta_1$ and $\theta_2$, suggested by de Boer, Segel, and Perelson to present the minimum field needed to stimulate the proliferation of the ...
arxiv +1 more source
Major components of fish immunity: a review [PDF]
, 2016 Fish are fascinating creatures with a certain degree of immunity comparable to those of mammals. The fish's immune system consists of two major components, innate and adaptive immunities.
Nawi, Mohd Firdaus, Saad, Mohd Zamri
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