Results 161 to 170 of about 49,620 (199)

Trained immunity: consequences for the heterologous effects of BCG vaccination

open access: yesTransactions of the Royal Society of Tropical Medicine and Hygiene, 2015
A growing body of evidence from epidemiologic and immunologic studies have shown that in addition to target disease-specific effects, vaccines have heterologous effects towards unrelated pathogens. Like some other vaccines, bacille Calmette-Guerin (BCG) has shown in observational studies and randomized clinical trials to increase survival beyond the ...
Kleinnijenhuis, J.   +2 more
openaire   +4 more sources

Heterologous immunity: an overlooked barrier to tolerance

Immunological Reviews, 2003
Summary:  In less than 50 years the field of organ transplantation has transitioned from an experimental concept to clinical commonplace. Notwithstanding the dramatic improvements in patient and allograft outcomes, chronic rejection and the complications from life‐long immunosuppressive therapy remain significant problems.
Andrew B, Adams   +2 more
openaire   +2 more sources

Heterologous Strain Immunity in Experimental Syphilis

The Journal of Immunology, 1951
Summary Quantitative techniques previously employed to measure homologous strain immunity in experimental syphilis have been extended to the measurement of heterologous strain immunity among three strains of Treponema pallidum in the rabbit.
H J, MAGNUSON, F A, THOMPSON
openaire   +2 more sources

Heterologous Immunity in Human Malaria

The Quarterly Review of Biology, 1973
Human hosts exposed to infection are model systems for studying the interactions of parasites with each other and with their environments. This paper uses published epidemiological data to demonstrate an interaction among the species of human malaria that is expected from ecological and evolutionary theory.
openaire   +2 more sources

Private specificities of heterologous immunity

Current Opinion in Immunology, 2006
Antiviral T-cell responses between individuals that have similar major histocompatibility complex molecules share similarities in epitope hierarchies and T-cell receptor variable gene usage (public specificities), yet the T-cell receptor amino acid sequences differ between individuals (private specificities).
openaire   +2 more sources

Heterologous immunity and the CD8 T cell network

Springer Seminars in Immunopathology, 2002
Over the course of a lifetime individuals develop a large complex pool of memory T cells that are specific for a variety of pathogens, including viruses, bacteria and parasites. The obvious role for memory T cells is to provide enhanced protection for an individual upon re-exposure to the original pathogen.
Liisa K, Selin   +3 more
openaire   +2 more sources

Heterologous immunity and homeostatic proliferation as barriers to tolerance

Current Opinion in Immunology, 2004
The different threshold of activation for memory T cells compared to that of naïve T cells makes them resistant to immunomodulation, thus representing a barrier to tolerance. Recently it has been demonstrated that homeostatic proliferation and heterologous immunity represent two naturally occurring and distinct processes that can generate memory T ...
Devon K, Taylor   +2 more
openaire   +2 more sources

Adaptation in the innate immune system and heterologous innate immunity

Cellular and Molecular Life Sciences, 2014
The innate immune system recognizes deviation from homeostasis caused by infectious or non-infectious assaults. The threshold for its activation seems to be established by a calibration process that includes sensing of microbial molecular patterns from commensal bacteria and of endogenous signals.
openaire   +3 more sources

Variation in protection by BCG: implications of and for heterologous immunity

The Lancet, 1995
Abstract Besides being the world's most widely used vaccine, and being directed against the world's leading cause of infectious disease mortality, BCG is the most controversial vaccine in current use. 1,2 Estimates of protection imparted by BCG against pulmonary tuberculosis vary from nil to 80%.
openaire   +2 more sources

Interference of oral immunization with the intestinal absorption of heterologous albumin

European Journal of Immunology, 1974
AbstractRats were immunized with human serum albumin (HSA) by a single intragastric administration of 200 mg of HSA. Two weeks later their capacity to absorb a similar intragastric test dose of HSA was found to be greatly impaired, the concentrations of HSA in mesenteric venous serum having been reduced to 33 %, 25 % and 60 % of those in similarly ...
C, André   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy