Archaeal Genes Code for GGDEF Domain Proteins With Diguanylate Cyclase Activity
A biofilm‐like mode of growth is hypothesized to be required for the emergence of cellular life. Occurrence of common biofilm gene products in current Bacteria and Archaea is an indication for their previous presence in the last universal common ancestor LUCA and perhaps even in the first universal common ancestor FUCA.
Roman Sidorov +6 more
wiley +1 more source
Bovine Adenovirus 3-Based Viral Vectors for Veterinary Vaccine Development: Progress, Limitations, and Future Directions. [PDF]
Sthitmatee N, Varinrak T, Kreausukon K.
europepmc +1 more source
Identification of new regulators of Arabidopsis IRT1 endocytosis and metal transport using TurboID. TurboID proximity labeling of the Arabidopsis IRT1 root metal transporter identified new IRT1‐interacting proteins upon different metal regimes. Among validated candidates, the endosome‐localized NHX5 Na+ (K+)/H+ antiporter and the plasma membrane ...
Liza Pellegrin +7 more
wiley +1 more source
Editorial: Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies
Shakti Singh +2 more
doaj +1 more source
The RING type ubiquitin ligase (E3), XBAT35.2, positively regulates FLS2‐mediated plant immunity against bacterial pathogens by modifying the ESCRT‐I subunits VPS28‐2 and VPS37‐1 with distinct ubiquitin chain types. Summary Sensing of pathogen‐associated molecular patterns (PAMPs) by pattern recognition receptors at the cell surface initiates the first
Chaofeng Wang +4 more
wiley +1 more source
Long-Term Durability and Dynamics of Anti-S-RBD IgG Response in Healthcare Workers: A Comparative Analysis of Homologous and Heterologous SARS-CoV-2 Vaccination Schedules in a 1-Year Serial Cross-Sectional Study. [PDF]
Demirel Ç +9 more
europepmc +1 more source
Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan +8 more
wiley +1 more source
Systemic and Mucosal Immune Responses From Serotype-Switched Viral-Vectored Ebola Vaccines. [PDF]
Wiggins J, Madapong A, Weaver E.
europepmc +1 more source
Bacteriophage P22 Virus‐Like Particles as Nanoscale Protein Scaffolds for Plant Synthetic Biology
ABSTRACT Advancing the utility of plant synthetic biology requires the continued development of protein engineering tools. Self‐assembling protein compartments, such as virus‐like particles (VLPs), provide versatile scaffolds for synthetic biology. However, few plant‐expressed VLPs have demonstrated broad amenability to protein engineering, restricting
Maxim D. Harding +5 more
wiley +1 more source
Swine Group A rotavirus vaccines: current status, adjuvant strategies, challenges, and future perspectives. [PDF]
Zhen Z +5 more
europepmc +1 more source

