Results 11 to 20 of about 2,661,263 (289)

Infection-acquired versus vaccine-acquired immunity in an SIRWS model [PDF]

, 2017
Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity.
Campbell, Patricia T, Frascoli, Federico, Hughes, Barry D, Leung, Tiffany, McCaw, James M   +4 more
core   +2 more sources

'Towards a Conceptual Framework for Innate Immunity' [PDF]

, 2005
Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
core   +3 more sources

Innate cell profiles during the acute and convalescent phase of SARS-CoV-2 infection in children

Nature Communications, 2021
Childhood infection with SARS CoV2 is associated with a milder course of infection but the immunopathogenesis of this remains unclear. Here the authors explore immunological differences in the innate immune system during acute and convalescent SARS CoV2 ...
Melanie R. Neeland, Samantha Bannister, Vanessa Clifford, Kate Dohle, Kim Mulholland, Philip Sutton, Nigel Curtis, Andrew C. Steer, David P. Burgner, Nigel W. Crawford, Shidan Tosif, Richard Saffery   +11 more
doaj   +1 more source

Lymphocyte-to-C-Reactive Protein Ratio as an Early Sepsis Biomarker for Neonates with Suspected Sepsis

Mediators of Inflammation, 2023
Background. Neonatal sepsis is an extremely dangerous and fatal disease among neonates, and its timely diagnosis is critical to treatment. This research is aimed at evaluating the clinical significance of the lymphocyte-to-C-reactive protein ratio (LCR ...
Xiaojuan Li, Yulei Wei, Zhe Xu, Tiewei Li, Geng Dong, Xinrui Liu, Zhiwei Zhu, Jianwei Yang, Junmei Yang   +8 more
doaj   +1 more source

mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort study protocol

BMJ Open, 2022
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment.
Daniel White, Sarah Bell, Shaun Oram, Robert Andrews, Mallinath Chakraborty, Sarah Edkins, W John Watkins, Patrícia R S Rodrigues, Angela Strang, Summia Zaher, Simran Sharma, Luke C Davies, Linda Moet, James E McLaren, Valerie B O’Donnell, Peter Ghazal, Edward Parkinson, Nicos Angelopoulos, Freya Shepherd, Kate Megan Megan Davies, Kate Siddall, Vikki Keeping, Kathryn Simpson, Federica Faggian, Maryanne Bray, Claire Bertorelli, Rachel E Collis, Mario Labeta   +27 more
doaj   +1 more source

Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity

Nature Communications, 2022
The presence of SARS-CoV-2-specific antibodies alone is not an accurate determinant of immunity. In this work, the authors investigate if whole-blood based measurement of SARS-CoV-2 specific T cell responses could prognosticate the risk of possible SARS ...
Martin J. Scurr, George Lippiatt, Lorenzo Capitani, Kirsten Bentley, Sarah N. Lauder, Kathryn Smart, Michelle S. Somerville, Tara Rees, Richard J. Stanton, Awen Gallimore, James P. Hindley, Andrew Godkin   +11 more
doaj   +1 more source

Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1

Scientific Reports, 2023
Natural killer (NK) cell subsets with adaptive properties are emerging as regulators of vaccine-induced T and B cell responses and are specialized towards antibody-dependent functions contributing to SARS-CoV-2 control.
Aljawharah Alrubayyi, Emma Touizer, Dan Hameiri-Bowen, Bethany Charlton, Ester Gea-Mallorquí, Noshin Hussain, Kelly A. S. da Costa, Rosemarie Ford, Chloe Rees-Spear, Thomas A. Fox, Ian Williams, Laura Waters, Tristan J. Barber, Fiona Burns, Sabine Kinloch, Emma Morris, Sarah Rowland-Jones, Laura E. McCoy, Dimitra Peppa   +18 more
doaj   +1 more source

libtissue - implementing innate immunity [PDF]

, 2006
In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems.
Aickelin, Uwe, Twycross, Jamie
core   +3 more sources

Integrative Genomics Reveals the Genetics and Evolution of the Honey Bee’s Social Immune System [PDF]

, 2019
Social organisms combat pathogens through individual innate immune responses or through social immunity—behaviors among individuals that limit pathogen transmission within groups.
Currie, Rob, Desai, Suresh, Foster, Leonard, Guarna, Maria Marta, Harpur, Brock, Higo, Heather, Hoover, Shelley, Huxter, Elizabeth, Ibrahim, Abdullah, Melathopoulos, Andony, Moon, Kyung-Mee, Pernal, Stephen, Zayed, Amro   +12 more
core   +1 more source

Harmonic balance surrogate-based immunity modeling of a nonlinear analog circuit [PDF]

, 2013
A novel harmonic balance surrogate-based technique to create fast and accurate behavioral models predicting, in the early design stage, the performance of nonlinear analog devices during immunity tests is presented.
Couckuyt, Ivo, Dhaene, Tom, Gazda, C, Pues, H, Rogier, Hendrik, Stijnen, K, Vande Ginste, Dries   +6 more
core   +2 more sources