Results 21 to 30 of about 1,593,818 (299)

IMMUNITY [PDF]

open access: yesInternational Economic Review, 2013
AbstractLegal provisions that protect elected politicians from prosecution have been common throughout history and still exist in most democracies. We provide the first systematic measurement of immunity and study, theoretically and empirically, its relation to corruption. Theory predicts that immunity is a double‐edged sword.
Karthik Reddy   +2 more
openaire   +6 more sources

Lymphocyte-to-C-Reactive Protein Ratio as an Early Sepsis Biomarker for Neonates with Suspected Sepsis

open access: yesMediators of Inflammation, 2023
Background. Neonatal sepsis is an extremely dangerous and fatal disease among neonates, and its timely diagnosis is critical to treatment. This research is aimed at evaluating the clinical significance of the lymphocyte-to-C-reactive protein ratio (LCR ...
Xiaojuan Li   +8 more
doaj   +1 more source

Innate cell profiles during the acute and convalescent phase of SARS-CoV-2 infection in children

open access: yesNature Communications, 2021
Childhood infection with SARS CoV2 is associated with a milder course of infection but the immunopathogenesis of this remains unclear. Here the authors explore immunological differences in the innate immune system during acute and convalescent SARS CoV2 ...
Melanie R. Neeland   +11 more
doaj   +1 more source

mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort study protocol

open access: yesBMJ Open, 2022
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment.
Daniel White   +27 more
doaj   +1 more source

Immune Thrombocytopenia [PDF]

open access: yesNew England Journal of Medicine, 2019
This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors’ clinical recommendations.
Cooper, Nichola, Ghanima, Waleed Khalid
openaire   +3 more sources

Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity

open access: yesNature Communications, 2022
The presence of SARS-CoV-2-specific antibodies alone is not an accurate determinant of immunity. In this work, the authors investigate if whole-blood based measurement of SARS-CoV-2 specific T cell responses could prognosticate the risk of possible SARS ...
Martin J. Scurr   +11 more
doaj   +1 more source

Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1

open access: yesScientific Reports, 2023
Natural killer (NK) cell subsets with adaptive properties are emerging as regulators of vaccine-induced T and B cell responses and are specialized towards antibody-dependent functions contributing to SARS-CoV-2 control.
Aljawharah Alrubayyi   +18 more
doaj   +1 more source

Maternal Immunization [PDF]

open access: yesClinical Infectious Diseases, 2014
Pregnant women, neonates, and infants are at higher risk for severe infections due to vaccine‐preventable diseases. Very young infants rarely respond well to vaccination due to poor immunogenicity and interference from maternal antibody. Maternal immunization protects the mother and fetus from disease and protects the infant through transplacental ...
Helen Y, Chu, Janet A, Englund
openaire   +4 more sources

The Role of Capsid in the Early Steps of HIV-1 Infection: New Insights into the Core of the Matter

open access: yesViruses, 2021
In recent years, major advances in research and experimental approaches have significantly increased our knowledge on the role of the HIV-1 capsid in the virus life cycle, from reverse transcription to integration and gene expression.
Nawal AlBurtamani   +2 more
doaj   +1 more source

Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo

open access: yesNature Communications, 2022
Plasma B cells (PC) are a potential source for protein replacement as they could be engineered to secrete protein other than antibody. Here the authors engineer B cells to express exogenous proteins and demonstrate that these cells can persist long term ...
Rene Yu-Hong Cheng   +11 more
doaj   +1 more source

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