Results 21 to 30 of about 4,133,580 (421)

'Towards a Conceptual Framework for Innate Immunity' [PDF]

open access: yes, 2005
Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
core   +3 more sources

Lymphocyte-to-C-Reactive Protein Ratio as an Early Sepsis Biomarker for Neonates with Suspected Sepsis

open access: yesMediators of Inflammation, 2023
Background. Neonatal sepsis is an extremely dangerous and fatal disease among neonates, and its timely diagnosis is critical to treatment. This research is aimed at evaluating the clinical significance of the lymphocyte-to-C-reactive protein ratio (LCR ...
Xiaojuan Li   +8 more
doaj   +1 more source

mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort study protocol

open access: yesBMJ Open, 2022
Introduction Maternal sepsis remains a leading cause of death in pregnancy. Physiological adaptations to pregnancy obscure early signs of sepsis and can result in delays in recognition and treatment.
Daniel White   +27 more
doaj   +1 more source

Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity

open access: yesNature Communications, 2022
The presence of SARS-CoV-2-specific antibodies alone is not an accurate determinant of immunity. In this work, the authors investigate if whole-blood based measurement of SARS-CoV-2 specific T cell responses could prognosticate the risk of possible SARS ...
Martin J. Scurr   +11 more
doaj   +1 more source

Immune privilege or privileged immunity? [PDF]

open access: yesMucosal Immunology, 2008
Immune privilege is a concept that has come of age. Where previously it was considered to be a passive phenomenon restricted to certain specialized tissues, it is now viewed as comprising several mechanisms, both active and passive, shared in many aspects with emerging notions of the mechanisms of peripheral tolerance.
Forrester, J.V.   +3 more
openaire   +4 more sources

Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1

open access: yesScientific Reports, 2023
Natural killer (NK) cell subsets with adaptive properties are emerging as regulators of vaccine-induced T and B cell responses and are specialized towards antibody-dependent functions contributing to SARS-CoV-2 control.
Aljawharah Alrubayyi   +18 more
doaj   +1 more source

PD-1 and its ligands in tolerance and immunity.

open access: yesAnnual Review of Immunology, 2008
Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, deliver inhibitory signals that regulate the balance between T cell activation, tolerance, and immunopathology.
M. Keir, M. Butte, G. Freeman, A. Sharpe
semanticscholar   +1 more source

Toll-Like Receptor Signaling and Its Role in Cell-Mediated Immunity

open access: yesFrontiers in Immunology, 2022
Innate immunity is the first defense system against invading pathogens. Toll-like receptors (TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition and induction of innate immune responses.
Tianhao Duan   +4 more
semanticscholar   +1 more source

A Test of Sovereignty: Franchise Tax Board of the State of California v. Gilbert P. Hyatt [PDF]

open access: yes, 2019
In Franchise Tax Board of California v. Hyatt, the Supreme Court considers whether to overrule Nevada v. Hall, a 1979 Supreme Court decision. Hall permitted a State to be haled into the court of another State without its consent.
Dill, Timothy
core   +5 more sources

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