Results 31 to 40 of about 2,498,524 (354)
Harmonic balance surrogate-based immunity modeling of a nonlinear analog circuit [PDF]
A novel harmonic balance surrogate-based technique to create fast and accurate behavioral models predicting, in the early design stage, the performance of nonlinear analog devices during immunity tests is presented.
Couckuyt, Ivo+6 more
core +2 more sources
Exploring the pre-immune landscape of antigen-specific T cells
Background Adaptive immune responses to newly encountered pathogens depend on the mobilization of antigen-specific clonotypes from a vastly diverse pool of naive T cells.
Mikhail V. Pogorelyy+11 more
doaj +1 more source
BackgroundChinese medical postgraduates (CMPs) are a special subpopulation that has a great risk of mental health due to high workload, and heavy academic and clinical pressure during the COVID-19 pandemic.
Cai-Ling Yue+5 more
doaj +1 more source
Beneficial autoimmunity at body surfaces – immune surveillance and rapid type 2 immunity regulate tissue homeostasis and cancer [PDF]
Epithelial cells line body surface tissues and provide a physicochemical barrier to the external environment. Frequent microbial and non-microbial challenges such as those imposed by mechanical disruption, injury or exposure to noxious environmental ...
Agrawal+190 more
core +2 more sources
Modeling the long term dynamics of pre-vaccination pertussis
The dynamics of strongly immunizing childhood infections is still not well understood. Although reports of successful modeling of several incidence data records can be found in the literature, the key determinants of the observed temporal patterns have ...
Ana Nunes+4 more
core +1 more source
Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]
Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Huitema, Edgar+3 more
core +2 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Due to the lack of specificity for tumor antigens, allogeneic T-cell therapy is associated with graft-versus-host disease. Enhancing the anti-tumor specificity while reducing the graft-versus-host disease risk of allogeneic T cells has remained a ...
Angelika Holler+9 more
doaj +1 more source
Longitudinal studies are defining progressive alterations to the immune system associated with increased mortality in the very elderly. Many of these changes are exacerbated by or even caused by chronic T cell stimulation by persistent antigen, particularly from Cytomegalovirus.
VASTO, Sonya, MALAVOLTA M, PAWELEC G.
openaire +5 more sources