Results 31 to 40 of about 3,965,028 (421)
Summary: With the growing appreciation of tissue-resident immunity, studying tissue-specific immune cells contributing to both homeostasis and disease is imperative.
Stephanie Kucykowicz+12 more
doaj
PD-1 and its ligands in tolerance and immunity.
Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, deliver inhibitory signals that regulate the balance between T cell activation, tolerance, and immunopathology.
M. Keir, M. Butte, G. Freeman, A. Sharpe
semanticscholar +1 more source
BackgroundChinese medical postgraduates (CMPs) are a special subpopulation that has a great risk of mental health due to high workload, and heavy academic and clinical pressure during the COVID-19 pandemic.
Cai-Ling Yue+5 more
doaj +1 more source
On the control of acute rodent malaria infections by innate immunity [PDF]
Does specific immunity, innate immunity or resource (red blood cell) limitation control the first peak of the blood-stage parasite in acute rodent malaria infections? Since mice deficient in specific immunity exhibit similar initial dynamics as wild-type
Antia, Rustom+3 more
core +3 more sources
This review presents data on changes in measures of innate and adaptive immunity associated with the state of sleep. The effects of restricted and prolonged sleep duration on measures of morbidity, mortality, and susceptibility to infectious diseases and the effects of vaccination are discussed.
openaire +5 more sources
The Role of Capsid in the Early Steps of HIV-1 Infection: New Insights into the Core of the Matter
In recent years, major advances in research and experimental approaches have significantly increased our knowledge on the role of the HIV-1 capsid in the virus life cycle, from reverse transcription to integration and gene expression.
Nawal AlBurtamani+2 more
doaj +1 more source
Plasma B cells (PC) are a potential source for protein replacement as they could be engineered to secrete protein other than antibody. Here the authors engineer B cells to express exogenous proteins and demonstrate that these cells can persist long term ...
Rene Yu-Hong Cheng+11 more
doaj +1 more source
Strength and weakness of disease-induced herd immunity in networks [PDF]
When a fraction of a population becomes immune to an infectious disease, the population-wide infection risk decreases nonlinearly due to collective protection known as herd immunity. Studies based on mean-field models suggest that natural infection in a heterogeneous population may induce herd immunity more efficiently than homogeneous immunization ...
arxiv
TLR4 links innate immunity and fatty acid-induced insulin resistance.
TLR4 is the receptor for LPS and plays a critical role in innate immunity. Stimulation of TLR4 activates proinflammatory pathways and induces cytokine expression in a variety of cell types.
Hang Shi+5 more
semanticscholar +1 more source
Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most clinical settings. Cancer is a systemic disease that induces many functional and compositional changes to the immune system as a whole.
Kamir J. Hiam-Galvez+2 more
semanticscholar +1 more source