Results 31 to 40 of about 3,965,028 (421)

Isolation of human intrahepatic leukocytes for phenotypic and functional characterization by flow cytometry

open access: yesSTAR Protocols, 2022
Summary: With the growing appreciation of tissue-resident immunity, studying tissue-specific immune cells contributing to both homeostasis and disease is imperative.
Stephanie Kucykowicz   +12 more
doaj  

PD-1 and its ligands in tolerance and immunity.

open access: yesAnnual Review of Immunology, 2008
Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, deliver inhibitory signals that regulate the balance between T cell activation, tolerance, and immunopathology.
M. Keir, M. Butte, G. Freeman, A. Sharpe
semanticscholar   +1 more source

The association between physical activity and mental health in medical postgraduates in China during COVID-19 pandemic

open access: yesFrontiers in Psychiatry, 2022
BackgroundChinese medical postgraduates (CMPs) are a special subpopulation that has a great risk of mental health due to high workload, and heavy academic and clinical pressure during the COVID-19 pandemic.
Cai-Ling Yue   +5 more
doaj   +1 more source

On the control of acute rodent malaria infections by innate immunity [PDF]

open access: yes, 2010
Does specific immunity, innate immunity or resource (red blood cell) limitation control the first peak of the blood-stage parasite in acute rodent malaria infections? Since mice deficient in specific immunity exhibit similar initial dynamics as wild-type
Antia, Rustom   +3 more
core   +3 more sources

Sleep and Immunity [PDF]

open access: yesNeuroscience and Behavioral Physiology, 2020
This review presents data on changes in measures of innate and adaptive immunity associated with the state of sleep. The effects of restricted and prolonged sleep duration on measures of morbidity, mortality, and susceptibility to infectious diseases and the effects of vaccination are discussed.
openaire   +5 more sources

The Role of Capsid in the Early Steps of HIV-1 Infection: New Insights into the Core of the Matter

open access: yesViruses, 2021
In recent years, major advances in research and experimental approaches have significantly increased our knowledge on the role of the HIV-1 capsid in the virus life cycle, from reverse transcription to integration and gene expression.
Nawal AlBurtamani   +2 more
doaj   +1 more source

Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo

open access: yesNature Communications, 2022
Plasma B cells (PC) are a potential source for protein replacement as they could be engineered to secrete protein other than antibody. Here the authors engineer B cells to express exogenous proteins and demonstrate that these cells can persist long term ...
Rene Yu-Hong Cheng   +11 more
doaj   +1 more source

Strength and weakness of disease-induced herd immunity in networks [PDF]

open access: yesarXiv, 2023
When a fraction of a population becomes immune to an infectious disease, the population-wide infection risk decreases nonlinearly due to collective protection known as herd immunity. Studies based on mean-field models suggest that natural infection in a heterogeneous population may induce herd immunity more efficiently than homogeneous immunization ...
arxiv  

TLR4 links innate immunity and fatty acid-induced insulin resistance.

open access: yesJournal of Clinical Investigation, 2006
TLR4 is the receptor for LPS and plays a critical role in innate immunity. Stimulation of TLR4 activates proinflammatory pathways and induces cytokine expression in a variety of cell types.
Hang Shi   +5 more
semanticscholar   +1 more source

Systemic immunity in cancer

open access: yesNature Reviews. Cancer, 2021
Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most clinical settings. Cancer is a systemic disease that induces many functional and compositional changes to the immune system as a whole.
Kamir J. Hiam-Galvez   +2 more
semanticscholar   +1 more source

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