Results 61 to 70 of about 3,965,028 (421)

Plain Reading, Subtle Meaning: Rethinking the IOIA and the Immunity of International Organizations [PDF]

, 2012
Immunity is freedom from liability, and as such, it can quite literally provide a “get out of jail free” card. In the United States, international organizations face uncertainty about the scope of their immunity, which is provided by the International ...
Adams, George B., III
core   +1 more source

Innate immunity and neuroinflammation [PDF]

, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core   +3 more sources

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

FEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard, Bernadette R. Gochuico, Hadass Pri Chen, Christopher K. E. Bleck, Patricia M. Zerfas, Wendy J. Introne, William A. Gahl, May C. V. Malicdan   +7 more
wiley   +1 more source

Section 1983: Absolute Immunity for Pretrial Police Testimony [PDF]

, 1987
This Note discusses the development of the Supreme Court\u27s approach to section 1983 immunity for trial witnesses. Central to this discussion is an overview of the history of common-law immunities for government officials, the history and purpose of ...
Kaufman, Jack
core   +1 more source

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

FEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang, Meritxell Wu‐Lu, Alberto Collauto, Peter‐Leon Hagedoorn, Madalina Alexandru, Maike Henschel, Shahram Kordasti, Maria Andrea Mroginski, Maxie M. Roessler, Kourosh H. Ebrahimi   +9 more
wiley   +1 more source

Cytomegalovirus-induced peroxynitrite promotes virus entry and contributes to pathogenesis in a murine model of infection

mBio
There are no licensed vaccines for human cytomegalovirus (HCMV), and current antiviral drugs that target viral proteins are toxic and prone to resistance.
Pragati S. Amratia, Lauren E. Kerr-Jones, Lucy Chapman, Morgan Marsden, Mathew Clement, Richard J. Stanton, Ian R. Humphreys   +6 more
doaj   +1 more source

IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction

Frontiers in Immunology, 2018
NK cells have potent antitumor capacity. They are enriched in the human liver, with a large subset specialized for tissue-residence. The potential for liver-resident versus liver-infiltrating NK cells to populate, and exert antitumor functions in, human ...
Nicholas J. W. Easom, Kerstin A. Stegmann, Leo Swadling, Laura J. Pallett, Alice R. Burton, Dennis Odera, Nathalie Schmidt, Wei-Chen Huang, Wei-Chen Huang, Giuseppe Fusai, Brian Davidson, Mala K. Maini   +11 more
doaj   +1 more source

Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study

BMC Medicine, 2020
Background There is an urgent need to develop biomarkers that stratify risk of bacterial infection in order to support antimicrobial stewardship in emergency hospital admissions.
Dayle Sampson, Thomas D. Yager, Brian Fox, Laura Shallcross, Leo McHugh, Therese Seldon, Antony Rapisarda, Richard B. Brandon, Krupa Navalkar, Nandi Simpson, Sian Stafford, Eliza Gil, Cristina Venturini, Evi Tsaliki, Jennifer Roe, Benjamin Chain, Mahdad Noursadeghi   +16 more
doaj   +1 more source

Clinical characteristics and risk factors for poor prognosis among HIV patients with Talaromyces marneffei bloodstream infection

BMC Infectious Diseases, 2021
Background Talaromyces marneffei (TM) bloodstream infection is common in Acquired Immunodeficiency Syndrome (AIDS) patients with extreme immunodeficiency in Southeast Asia and South China, however, clinical case study on TM bloodstream infection is ...
Jianjun Sun, Weiwei Sun, Yang Tang, Renfang Zhang, Li Liu, Yinzhong Shen, Jiangrong Wang, Jun Chen, Tangkai Qi, Zhenyan Wang, Wei Song, Yixiao Lin, Shuibao Xu, Hongzhou Lu   +13 more
doaj   +1 more source

\u3ci\u3eAltmann v. Austria\u3c/i\u3e and the Retroactivity of the Foreign Sovereign Immunities Act [PDF]

, 2005
In Republic of Austria v. Altmann, the U.S. Supreme Court decided that the Foreign Sovereign Immunities Act of 1976 (FSIA) generally applies to claims based on events that occurred before the Statute\u27s enactment.
Vázquez, Carlos Manuel
core   +1 more source