Results 61 to 70 of about 2,498,524 (354)
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction
Frontiers in Immunology, 2018 NK cells have potent antitumor capacity. They are enriched in the human liver, with a large subset specialized for tissue-residence. The potential for liver-resident versus liver-infiltrating NK cells to populate, and exert antitumor functions in, human ...
Nicholas J. W. Easom +11 more
doaj +1 more source
BMC Infectious Diseases, 2021 Background Talaromyces marneffei (TM) bloodstream infection is common in Acquired Immunodeficiency Syndrome (AIDS) patients with extreme immunodeficiency in Southeast Asia and South China, however, clinical case study on TM bloodstream infection is ...
Jianjun Sun +13 more
doaj +1 more source
Wild Westworld: Section 230 of the CDA and Social Networks’ Use of Machine-Learning Algorithms [PDF]
, 2017 This Note argues that Facebook’s services—specifically the personalization of content through machine-learning algorithms—constitute the “development” of content and as such do not qualify for § 230 immunity.
Tremble, Catherine
core +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function
Nature Communications, 2019 Increasing TCR cell surface expression can potentiate T cell responses to low-concentrations of antigen. Here the authors identify aminoacids in human TCR variable domains that impact its surface expression, and demonstrate how editing these residues can
Sharyn Thomas +16 more
doaj +1 more source
A Test of Sovereignty: Franchise Tax Board of the State of California v. Gilbert P. Hyatt [PDF]
, 2019 In Franchise Tax Board of California v. Hyatt, the Supreme Court considers whether to overrule Nevada v. Hall, a 1979 Supreme Court decision. Hall permitted a State to be haled into the court of another State without its consent.
Dill, Timothy
core +1 more source
Scientific Reports, 2017 Pathogen-associated biliary fibrosis (PABF) is a type of liver fibrosis characterized by injuries of cholangiocytes and extra cellular matrix (ECM) deposition around bile ducts caused by various bacteria, fungi, virus and parasites.
Chao Yan +11 more
doaj +1 more source
Frontiers in Microbiology, 2016 Protein phosphatase 1 (PP1c) is one of the main phosphatases whose function is shaped by many regulators to confer a specific location and a selective function for this enzyme. Here, we report that eukaryotic initiation factor 2 of P.
Géraldine eTellier +11 more
doaj +1 more source
Scientific Reports, 2021 To understand the contribution of mononuclear phagocytes (MNP), which include monocyte-derived intestinal macrophages, to the pathogenesis of inflammatory bowel disease (IBD), it is necessary to identify functionally-different MNP populations.
Pamela B. Wright +13 more
doaj +1 more source