Cutaneous lesions in psoriatic arthritis are enriched in chemokine transcriptomic pathways
Arthritis Research & Therapy, 2023 Objectives Skin from people with psoriasis has been extensively studied and is assumed to be identical to skin from those with psoriatic arthritis (PsA).
Hanna Johnsson +4 more
doaj +1 more source
Section 1983: Absolute Immunity for Pretrial Police Testimony [PDF]
, 1987 This Note discusses the development of the Supreme Court\u27s approach to section 1983 immunity for trial witnesses. Central to this discussion is an overview of the history of common-law immunities for government officials, the history and purpose of ...
Kaufman, Jack
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libtissue - implementing innate immunity [PDF]
, 2006 In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems.
Aickelin, Uwe, Twycross, Jamie
core +3 more sources
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
STEAP4 expression in CNS resident cells promotes Th17 cell-induced autoimmune encephalomyelitis
Journal of Neuroinflammation, 2021 Background Multiple sclerosis (MS) is a debilitating neurological disease caused by autoimmune destruction of the myelin sheath. Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for the pathogenesis of MS.
Junjie Zhao +7 more
doaj +1 more source
\u3ci\u3eAltmann v. Austria\u3c/i\u3e and the Retroactivity of the Foreign Sovereign Immunities Act [PDF]
, 2005 In Republic of Austria v. Altmann, the U.S. Supreme Court decided that the Foreign Sovereign Immunities Act of 1976 (FSIA) generally applies to claims based on events that occurred before the Statute\u27s enactment.
Vázquez, Carlos Manuel
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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
Science, 2020 Immune profiling of COVID-19 patients Coronavirus disease 2019 (COVID-19) has affected millions of people globally, yet how the human immune system responds to and influences COVID-19 severity remains unclear. Mathew et al.
P. Arunachalam +30 more
semanticscholar +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
mBioThere are no licensed vaccines for human cytomegalovirus (HCMV), and current antiviral drugs that target viral proteins are toxic and prone to resistance.
Pragati S. Amratia +6 more
doaj +1 more source
Plain Reading, Subtle Meaning: Rethinking the IOIA and the Immunity of International Organizations [PDF]
, 2012 Immunity is freedom from liability, and as such, it can quite literally provide a “get out of jail free” card. In the United States, international organizations face uncertainty about the scope of their immunity, which is provided by the International ...
Adams, George B., III
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