Results 161 to 170 of about 14,479 (218)

Trop2 immuno-PET/CT imaging of prostate cancer: a proof-of-concept translational study. [PDF]

open access: yesBMC Med
Long X   +7 more
europepmc   +1 more source

Immuno-PET Molecular Imaging of RANKL in Cancer. [PDF]

open access: yesCancers (Basel), 2021
Dewulf J   +7 more
europepmc   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang   +6 more
wiley   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

open access: yesAngewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann   +23 more
wiley   +2 more sources

The impact of weakly bound 89Zr on preclinical studies: Non-specific accumulation in solid tumors and aspergillus infection [PDF]

open access: yes, 2015
Hansen, Anders Elias   +9 more
core   +1 more source

Predictive Value of Circulating Tumor Cells in Neoadjuvant Chemoimmunotherapy for Non‐Small Cell Lung Cancer

open access: yesThoracic Cancer, Volume 17, Issue 9, May 2026.
Preoperative CK+ CTC monitoring may serve as a promising adjunct to conventional imaging for predicting pathological response in patients receiving neoadjuvant chemoimmunotherapy. Our exploratory findings suggest that systemic CTC dissemination is associated with a microenvironmental convergence of local hypoxia and attenuated immune signaling ...
Jianyi Yang   +11 more
wiley   +1 more source

Pretargeted Immuno-PET Enables Monoclonal Antibody Imaging Beyond the Blood-Brain Barrier. [PDF]

open access: yesMol Pharm
Gustavsson T   +17 more
europepmc   +1 more source

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