Results 41 to 50 of about 712 (146)

Activation of cGAS‐STING by Lethal Malaria N67C Dictates Immunity and Mortality through Induction of CD11b+Ly6Chi Proinflammatory Monocytes

Advanced Science, Volume 9, Issue 22, August 5, 2022., 2022
Cyclic GMP‐AMP synthase (cGAS) and stimulator of interferon genes (STING) play critical roles in innate immunity against infectious diseases, while the mechanisms that cGAS‐STING‐induced cytokines suppress immune response against malaria infection remain poorly understood.
Yang Du, Yien Luo, Zhiqiang Hu, Jiansen Lu, Xin Liu, Changsheng Xing, Jian Wu, Tianhao Duan, Junjun Chu, Helen Y. Wang, Xin‐zhuan Su, Xiao Yu, Rong‐Fu Wang   +12 more
wiley   +1 more source

IMMUNOMODULATORY PROPERTIES OF THE HUMAN INTESTINAL MICROBIOTA AND PROSPECTS FOR THE USE OF PROBIOTICS FOR PROPHYLAXIS AND CORRECTION OF INFLAMMATORY PROCESSES [PDF]

Biotechnologia Acta, 2015
Literature data and own author experiments concerning the influence of microbiota on the immune system are summarized. The mechanisms of the diversification of immune response to pathogenic and commensal microorganisms are described.
Skivka L. M.
doaj   +1 more source

Immunoregulatory effects triggered by immunobiotic Lactobacillus jensenii TL2937 strain involve efficient phagocytosis in porcine antigen presenting cells [PDF]

, 2016
Background: Immunobiotic Lactobacillus jensenii TL2937 modulates porcine mononuclear phagocytes from Peyer?s patches (PPMPs) and induces a differential production of pro- and anti-inflammatory cytokines in response to Toll-like receptor (TLR)-4 ...
Aso, Hisashi, Iida, Hikaru, Kanmani, Paulraj, Kano, Hiroshi, Kitazawa, Haruki, Makino, Seiya, Nochi, Tomonori, Ohkawara, Sou, Ohwada, Shuichi, Saito, Tadao, Suda, Yoshihito, Takahashi, Takuya, Tsukida, Kohichiro, Villena, Julio Cesar   +13 more
core   +3 more sources

Draft Genome Sequence of the Immunobiotic Strain Lactobacillus jensenii TL2937 [PDF]

Genome Announcements, 2017
ABSTRACT The genome of the immunomodulatory strain Lactobacillus jensenii TL2937 is described here. The draft genome has a total length of 1,678,416 bp, a G+C content of 34.3%, and 1,470 predicted protein-coding sequences.
Julio Villena, Yuki Masumizu, Hikaru Iida, Wakako Ikeda-Ohtsubo, Leonardo Albarracin, Seiya Makino, Sou Ohkawara, Katsunori Kimura, Lucila Saavedra, Elvira Maria Hebert, Haruki Kitazawa   +10 more
openaire   +3 more sources

The Exopolysaccharide of Lactobacillus fermentum UCO-979C Is Partially Involved in Its Immunomodulatory Effect and Its Ability to Improve the Resistance against Helicobacter pylori Infection

Microorganisms, 2020
Lactobacillus fermentum UCO-979C (Lf979C) beneficially modulates the cytokine response of gastric epithelial cells and macrophages after Helicobacter pylori infection in vitro.
Valeria Garcia-Castillo, Guillermo Marcial, Leonardo Albarracín, Mikado Tomokiyo, Patricia Clua, Hideki Takahashi, Haruki Kitazawa, Apolinaria Garcia-Cancino, Julio Villena   +8 more
doaj   +1 more source

Immunobiotics: Interactions of Beneficial Microbes with the Immune System [PDF]

, 2018
The term “immunobiotics” has been proposed to define microbial strains able to beneficially regulate the mucosal immune system. Research in immunobiotics has significantly evolved as researchers employed cutting-edge technologies to investigate the complex interactions of these beneficial microorganisms with the immune system.
Haruki Kitazawa, Julio Villena
openaire   +3 more sources

Regulation of Toll-like receptors-mediated inflammation by immunobiotics in bovine intestinal epitheliocytes: role of signalling pathways and negative regulators

Frontiers in Immunology, 2014
Intestinal epithelial cells (IECs) detect bacterial and viral associated-molecular-patterns (MAMPs) via germline-encoded pattern-recognition receptors (PRRs) and are responsible for maintaining immunetolerance to the communities of resident commensal ...
Julio eVillena, Hisashi eAso, Haruki eKitazawa   +2 more
doaj   +1 more source

Modulation of porcine intestinal epitheliocytes immunetranscriptome response by Lactobacillus jensenii TL2937 [PDF]

, 2016
In order to evaluate probiotic strains applicable for the beneficial immunomodulation of the porcine gut (immunobiotics), we previously developed a porcine intestinal epitheliocyte cell line (PIE cells).
Albarracín, Leonardo Miguel, Aso, Hisashi, Ikeda-Ohtsubo, Wakako, Kanmani, Paulraj, Kano, Hiroshi, Kitazawa, Haruki, Kobayashi, Hisakazu, Kober, Humayun A.K.M., Makino, Seiya, Nochi, Tomonori, Ohkawara, Sou, Saito, Tadao, Sato, Nana, Suda, Yoshihito, Villena, Julio Cesar   +14 more
core   +1 more source

Immunobiotics and the probiotic evolution [PDF]

FEMS Immunology & Medical Microbiology, 2003
The term 'probiotic' was coined by the food industry to describe microbes beneficial to health. Scientific criticism based on poorly characterised isolates, soft clinical targets, and an absence of a mechanistic framework limited value of this concept.
openaire   +2 more sources

Immunobiotic and Paraprobiotic Potential Effect of Lactobacillus casei in a Systemic Toxoplasmosis Murine Model. [PDF]

Microorganisms, 2020
One of the main characteristics of probiotics is their ability to stimulate and modulate the immune response regardless of their viability. Lactobacillus casei (Lc) can stimulate local and systemic immunity, in addition to the activation of macrophages at sites distant from the intestine.
Salas-Lais AG, Robles-Contreras A, Balderas-López JA, Bautista-de Lucio VM.   +3 more
europepmc   +5 more sources