Immunocastration in adult boars as a model for late‐onset hypogonadism
Andrology, 2022 Abstract Background While immunocastration has been studied in male pre‐pubertal pigs, data on older, sexually mature animals are limited. To understand the physiological effects of androgen deprivation in the late sexual development phase, we compared mature immunocastrated boars (n = 19; average age = 480 days) to young male immunocastrated pigs (n =
Nina Batorek Lukac, Martin Škrlep
exaly +5 more sources
INSL3 Expression in Leydig Cells is a Biomarker for Immunocastration in Boars: Transcriptional Evidence. [PDF]
AndrologyABSTRACT Background Study aimed to obtain insights into physiological responses to immunocastration in pubertal boars by evaluating effects of alternative vaccination protocols and identifying a reliable immunocastration biomarker. Objectives It was hypothesized that the timing of gonadotropin‐releasing hormone (GnRH) suppression by immunocastration ...
Lukač NB +6 more
europepmc +7 more sources
Delivering an Immunocastration Vaccine via a Novel Subcutaneous Implant [PDF]
Animals, 2022 Immunocastration relies on the vaccine-mediated stimulation of an immune response to gonadotropin-releasing hormone (GnRH) in order to interrupt spermatogenesis. This approach offers a less painful alternative to traditional castration approaches but the current, commercially available options require multiple doses of vaccine to maintain sterility ...
Michael Kleinhenz +2 more
exaly +6 more sources
Sustainability of Pork Production with Immunocastration in Europe [PDF]
Sustainability, 2019 Immunocastration, a technique to replace surgical castration of piglets, consists of two consecutive vaccinations to induce antibodies which transiently suppress testicular functions and avoid boar taint. It is a method to ensure both a high product quality and a high level of animal welfare.
Volker Stefanski +2 more
exaly +5 more sources
Effectiveness of a New Recombinant antiGnRH Vaccine for Immunocastration in Bulls [PDF]
Animals, 2021 Castration by surgical techniques is common in livestock; however, post-surgery complications and concerns for animal wellbeing have created a need for new non-invasive alternatives. The objective of this study was to evaluate immunocastration in bulls using antigen GnRX G/Q; a recombinant peptide proved to be effective in laboratory and companion ...
Leonardo Saenz
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Reproductive and Behavioral Evaluation of a New Immunocastration Dog Vaccine [PDF]
Animals, 2020 Canine immunocastration development has been of interest for many years as a complementary strategy to surgical castration. The purpose of this paper was to verify the effect of a recombinant vaccine for dog immunocastration. Two tests were done, one under controlled conditions and a second under field conditions. Animals were injected with 1 mL of 500
Leonardo Saenz +2 more
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Effect of GnRH immunocastration on immune function in male rats
Frontiers in Immunology, 2023 The present study aimed to reveal the effects of immunocastration on the development of the immune system in rats. Seventy rats were randomly assigned into two groups: Control (n = 35) and immunized (n = 35). Twenty-day-old rats were immunized with gonadotropin-releasing hormone (GnRH) and booster immunization was administered every two weeks (three ...
Fang Fugui, Li Yunsheng, Ling Yinghui
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GnRH-immunocastration: an alternative method for male animal surgical castration [PDF]
Frontiers in Veterinary Science, 2023 Zeng Yutian
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Efficiency of immunocastration with an anti-gonadotropin-releasing hormone vaccine on cryptorchid bulls [PDF]
Journal of Veterinary Medical Science, 2023 Yoichi Inoue, Keiichi Hisaeda
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GnRH Immunocastration in Male Xizang Sheep: Impacts on Rumen Microbiome and Metabolite Profiles for Enhanced Health and Productivity [PDF]
AnimalsXunping Jiang, , Guiqiong Liu
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