A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi +10 more
wiley +1 more source
Synthesis of Tetrahydro-β-Carboline-Based Spirocyclic Peptides via Cascade N-Boc Deprotection and Pictet-Spengler Reaction of Tryptophan: Potent Anti-Inflammatory and Anti-Oxidant Activities. [PDF]
Battula S +3 more
europepmc +1 more source
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão +5 more
wiley +1 more source
Correction to "Validation of on-slide immunocytochemistry controls prepared from long-term preserved prefixed cell suspensions". [PDF]
europepmc +1 more source
A proteomic signature of oocyte quality from models of varying oocyte developmental competence. [PDF]
Frost ER +11 more
europepmc +1 more source
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma +15 more
wiley +1 more source
Validation of on-slide immunocytochemistry controls prepared from long-term preserved prefixed cell suspensions. [PDF]
Roque RR +6 more
europepmc +1 more source
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
Biological Characteristics of Stromal Cells Differ Between Primary Lung Adenocarcinoma, Peritumoral Lung, and Distal Lung Tissues. [PDF]
Kamimura G +7 more
europepmc +1 more source
A case report of concomitant anti-glomerular basement membrane disease, IgA nephropathy, and membranous nephropathy. [PDF]
Zheng J, Yu X, Lin X, Guo H.
europepmc +1 more source

