Immunofluorescence identifies distinct subsets of endothelial cells in the human liver
Scientific Reports, 2017 As well as systemic vascular endothelial cells, the liver has specialised sinusoidal endothelial cells (LSEC). LSEC dysfunction has been documented in many diseased states yet their phenotype in normal human liver has not been comprehensively assessed ...
Otto Strauss +4 more
semanticscholar +1 more source
UV micro-irradiation of the Chinese hamster cell nucleus and caffeine post-treatment immunocytochemical localization of DNA photolesions in cells with partial and generalized chromosome shattering [PDF]
, 1983 UV micro-irradiation of a small part of the Chinese hamster nucleus and caffeine post-incubation often results in shattered chromosomes at the first post-irradiation mitosis.
Cornelis +26 more
core +1 more source
Seed-produced anti-globulin VHH-Fc antibodies retrieve globulin precursors in the insoluble fraction and modulate the Arabidopsis thaliana seed subcellular morphology [PDF]
, 2020 Key message Nanobody-heavy chain (VHH-Fc) antibody formats have the potential to immunomodulate even highly accumulating proteins and provide a valuable tool to experimentally modulate the subcellular distribution of seed storage proteins.
Altmann, Friedrich +7 more
core +2 more sources
Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity.
JCI Insight, 2017 Intestinal tuft cells are a rare, poorly understood cell type recently shown to be a critical mediator of type 2 immune response to helminth infection.
Eliot T. McKinley +12 more
semanticscholar +1 more source
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA [PDF]
, 2012 Topoisomerase II creates a double-strand break intermediate with topoisomerase covalently coupled to the DNA via a 5'-phosphotyrosyl bond. These intermediate complexes can become cytotoxic protein-DNA adducts and DSB repair at these lesions requires ...
Austin, Caroline +10 more
core +3 more sources
Scientific Data, 2019 In this data descriptor, we document a dataset of multiplexed immunofluorescence images and derived single-cell measurements of immune lineage and other markers in formaldehyde-fixed and paraffin-embedded (FFPE) human tonsil and lung cancer tissue.
R. Rashid +11 more
semanticscholar +1 more source
Non-Measles Hemadsorption in a Cell Line Persistently Infected with Measles Virus (BGM/MV) [PDF]
, 1981 Adsorption of Rhesus monkey erythrocytes to the plasma membranes of measles virus infected cells is frequently carried out to detect the presence of plasma membrane-associated measles virus hemagglutinin.
May, John D., Menna, Jay H.
core +2 more sources
T-2 Toxin-Induced Hepatotoxicity in HepG2 Cells Involves the Inflammatory and Nrf2/HO-1 Pathways
ToxinsThe T-2 toxin is one of the most toxic mycotoxins, to which the population is exposed through the diet. T-2 toxins are especially found in cereals and cereal-based products.
Mercedes Taroncher +3 more
doaj +1 more source
Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase‐20 in human cancers
Cancer Medicine, 2019 Background Matrix metalloproteinases‐20 (MMP20) expression is widely regarded as tooth specific, with expression limited to dental hard tissues. Recently, we reported MMP20 expression and interaction with dentin sialophosphoprotein (DSPP), a member of ...
Jaya Aseervatham +4 more
doaj +1 more source
Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex. [PDF]
, 2018 Numerous types of inhibitory neurons sculpt the performance of human neocortical circuits, with each type exhibiting a constellation of subcellular phenotypic features in support of its specialized functions.
Chang, Edward F +9 more
core +1 more source