Results 111 to 120 of about 723,902 (263)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Immunofluorescence Antibodies Applied for Staining.

, 2016
Immunofluorescence Antibodies Applied for Staining.
Salvador Garcia Mojica (849375), Kathleen A. Holoyda (3179436), Xiaogang Hou (849378), Christopher R. Schlieve (3179439), Kathryn L. Fowler (3179433), Tracy C. Grikscheit (300701)   +5 more
core   +1 more source

Impact of molecular diagnostic techniques on the acute respiratory infection sentinel surveillance program, Antioquia, Colombia, 2022

Frontiers in Epidemiology
ObjectivesSurveillance of acute respiratory infection (ARI) informs vaccination, preventive, and management decisions. In many countries, immunofluorescence is the cornerstone for ARI surveillance.
María Angélica Maya, Celeny Ortiz, Francisco Averhoff, Francisco Averhoff, Mabel Carabali, Laura S. Pérez-Restrepo, Laura S. Pérez-Restrepo, Laura S. Pérez-Restrepo, Karl Ciuoderis-Aponte, Karl Ciuoderis-Aponte, Karl Ciuoderis-Aponte, Ana Isabel Davila, Diego Bastidas, Seti Buitrago, Gavin A. Cloherty, Gavin A. Cloherty, Michael G. Berg, Michael G. Berg, Alan Landy, Juan P. Hernandez-Ortiz, Juan P. Hernandez-Ortiz, Juan P. Hernandez-Ortiz, Paulina A. Rebolledo, Jorge E. Osorio, Jorge E. Osorio, Jorge E. Osorio, Jorge E. Osorio   +26 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Antibodies used for immunofluorescence staining.

, 2015
Antibodies used for immunofluorescence staining.
Richard O. Hynes (239663), Shahinoor Begum (711481), Patrick A. Murphy (711480)   +2 more
core   +1 more source

FREQUÊNCIA DE ANTICORPOS ANTI- Toxoplasma gondii EM PROPRIEDADES DE CRIAÇÃO DE CAPRINOS E OVINOS NO ESTADO DE PERNAMBUCO

Ciência Animal Brasileira, 2011
The present study was carried out in order to verify the presence of anti-Toxoplasma gondii antibodies in goat and sheep farms located in different mesoregions within the State of Pernambuco – Brazil. Blood samples were collected from 1 64 goats and 1 24
MANOEL DE SOUZA BISPO, MARIA APARECIDA DA GLORIA FAUSTINO, LEUCIO CÂMARA ALVES, JOAQUÍN HERNÁN PATARROYO SALCEDO, CARLOS HENRIQUE DE SOUZA, DALIANE PONTES DE SOUSA, MARILENE MARIA DE LIMA   +6 more
doaj  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Antibodies used in immunofluorescence studies.

, 2015
Antibodies used in immunofluorescence studies.
Juliana D. Lourenço (571144), Chin J. Lin (751359), Beatriz M. Saraiva-Romanholo (751361), Sérgio D. Sasaki (5663998), Milton A. Martins (3264867), Clarice R. Olivo (571146), Natália G. Gonçalves (751357), Fernanda Degobbi T. Q. S. Lopes (751362), Walcy R. Teodoro (587150), Fabíola S. Z. Robertoni (751356), Ana Paula P. Velosa (751358), Cláudia M. Fló (751360)   +11 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source