Results 11 to 20 of about 456,969 (387)
Biomaterials Research, 2023 Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to address the donor shortage as well as immunologic rejection attributed to cells in conventional tissue/organ transplantation.
Mohammadreza Kasravi +7 more
semanticscholar +1 more source
Safety, Immunogenicity, and Efficacy of the BNT162b2 Covid-19 Vaccine in Adolescents
New England Journal of Medicine, 2021 Background Until very recently, vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had not been authorized for emergency use in persons younger than 16 years of age.
R. Frenck +25 more
semanticscholar +1 more source
Experimental and Molecular Medicine, 2023 Several studies have utilized a lipid nanoparticle delivery system to enhance the effectiveness of mRNA therapeutics and vaccines. However, these nanoparticles are recognized as foreign materials by the body and stimulate innate immunity, which in turn ...
Yeji Lee +4 more
semanticscholar +1 more source
Immunogenicity of autoantigens [PDF]
BMC Genomics, 2011 Autoantibodies against self-antigens have been associated not only with autoimmune diseases, but also with cancer and are even found in healthy individuals. The mechanism causing the autoantibody response remains elusive for the majority of the immunogenic antigens. To deepen the understanding of autoantibody responses, we ask whether natural-occurring,
Eckart Meese +7 more
openaire +4 more sources
Annals of the Rheumatic Diseases, 2021 Introduction Vaccination represents a cornerstone in mastering the COVID-19 pandemic. Data on immunogenicity and safety of messenger RNA (mRNA) vaccines in patients with autoimmune inflammatory rheumatic diseases (AIIRD) are limited.
V. Furer +28 more
semanticscholar +1 more source
Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates
New England Journal of Medicine, 2020 Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the resulting disease, coronavirus disease 2019 (Covid-19), have spread to millions of persons worldwide.
E. Walsh +24 more
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2021 Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients Immunocompromised individuals have been excluded from studies of SARS-CoV-2 messenger RNA (mRNA) vaccines.
B. Boyarsky +6 more
semanticscholar +1 more source
Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women.
Journal of the American Medical Association (JAMA), 2021 Importance Pregnant women are at increased risk of morbidity and mortality from COVID-19 but have been excluded from the phase 3 COVID-19 vaccine trials. Data on vaccine safety and immunogenicity in these populations are therefore limited. Objective To
Ai-ris Y. Collier +27 more
semanticscholar +1 more source
Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination
Nature Network Boston, 2021 Heterologous priming with the ChAdOx1 nCoV-19 vector vaccine followed by boosting with a messenger RNA vaccine (BNT162b2 or mRNA-1273) is currently recommended in Germany, although data on immunogenicity and reactogenicity are not available.
T. Schmidt +14 more
semanticscholar +1 more source
Immunogenicity of CRISPR therapeutics—Critical considerations for clinical translation
Frontiers in Bioengineering and Biotechnology, 2023 CRISPR offers new hope for many patients and promises to transform the way we think of future therapies. Ensuring safety of CRISPR therapeutics is a top priority for clinical translation and specific recommendations have been recently released by the FDA.
Radwa Ewaisha, K. Anderson
semanticscholar +1 more source