Results 221 to 230 of about 350,984 (342)

Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives

Advanced Materials, EarlyView.
Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin, Liliang Ouyang, Khoon S. Lim, Antonella Motta, Devid Maniglio, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Safety and immunogenicity of an mRNA-based RSV vaccine in seropositive children aged 12-59 months. [PDF]

Hum Vaccin Immunother
Schnyder Ghamloush S, Fanning S, Essink B, Eder F, Snape MD, Stoszek SK, Guo R, Dhar R, Righi V, Morsy L, Kapoor A, El Asmar L, Shaw CA.   +12 more
europepmc   +1 more source

Probiotic‐Based Materials as Living Therapeutics

Advanced Materials, EarlyView.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio, Graham J. Day, Manuel Salmeron‐Sanchez   +2 more
wiley   +1 more source

HLA-DRB1*15:01 is associated with a reduced likelihood of longevity in northern European men. [PDF]

Genome Med
Mendoza-Mejía N, Kolbe D, Özer O, Dose J, Torres GG, Franke A, Nygaard M, Nebel A.   +7 more
europepmc   +1 more source

Quantitative studies of translymphnodal passage of tumour cells naturally disseminated from a non-immunogenic murine squamous carcinoma [PDF]

, 1975
H B Hewitt, E R Blake
openalex   +1 more source

Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy

Advanced Materials, EarlyView.
Weakly assembled peptide amphiphile nanostructures disassemble in circulation and reassemble with blood biomolecules, mainly lipoproteins. Binding to blood biomolecules prolongs blood circulation and improves accumulation in solid tumors. In the tumor microenvironment, peptide amphiphiles assemble with cholesterol‐rich domains of cell membranes ...
Li Xiang, Morgan R. Stewart, Kailin Mooney, Mingchong Dai, Samuel Drennan, Samantha Holland, Arnaud Quentel, Sinan Sabuncu, Benjamin R. Kingston, Isabel J. Dengos, Karla Bonic, Florian Goncalves, Xin Yi, Michael I. Henderson, Srivathsan Ranganathan, Bruce P. Branchaud, Leslie L. Muldoon, Ramon F. Barajas Jr, Jared M. Fischer, Adem Yildirim   +19 more
wiley   +1 more source

Quadrivalent HPV Vaccine Evaluation Study with Addition of the Nonavalent Vaccine (QUEST-ADVANCE): protocol of an observational cohort study. [PDF]

BMJ Open
Middeldorp M, Donken R, Nirmal A, Smith B, Citlali Marquez A, Bettinger JA, Brisson M, Burchell AN, Dobson SR, Dawar M, Franco EL, Grennan T, Krajden M, Mayrand MH, McNeil S, Naus M, Sauvageau C, Singer J, Smith LW, Ogilvie GS, Sadarangani M.   +20 more
europepmc   +1 more source

A Programmable Nanovaccine Platform Based on M13 Bacteriophage for Personalized Cancer Vaccine and Therapy

Advanced Materials, EarlyView.
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang, Yanpu He, Allison Madow, Huaiyao Peng, Mirielle Griffin, Jifa Qi, Mantao Huang, Heather Amoroso, Riley Abrashoff, Nimrod Heldman, Angela M. Belcher   +10 more
wiley   +1 more source

Farm animal coronaviruses: the solution is in vaccines. [PDF]

Vet Q
Kondakova O, Tsybina A, Evtushenko E, Ryabchevskaya E, Granovskiy D, Kovalenko A, Arkhipenko M, Nikitin N, Karpova O.   +8 more
europepmc   +1 more source

Tailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics

Advanced Materials, EarlyView.
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding, Wenhao Li, Ling Mei, Suling Luo, Jing Tao, Chongxiu Shi, Hongping Yang, Wei Feng, Yungchang Chen, Yu Chen, Jong Seung Kim, Xue Shen   +11 more
wiley   +1 more source