Results 31 to 40 of about 844,089 (291)

Extensive age-dependent loss of antibody diversity in naturally short-lived turquoise killifish

eLife, 2022
Aging individuals exhibit a pervasive decline in adaptive immune function, with important implications for health and lifespan. Previous studies have found a pervasive loss of immune-repertoire diversity in human peripheral blood during aging; however ...
William John Bradshaw, Michael Poeschla, Aleksandra Placzek, Samuel Kean, Dario Riccardo Valenzano   +4 more
doaj   +1 more source

Serum Free Light Chains in Common Variable Immunodeficiency Disorders: Role in Differential Diagnosis and Association With Clinical Phenotype

Frontiers in Immunology, 2020
We report on an observational, multicenter study of 345 adult CVID patients, designed to assess the diagnostic value and the clinical association of serum free light chain (sFLC) pattern in Common Variable Immunodeficiency disorders (CVID).
Riccardo Scarpa, Riccardo Scarpa, Federica Pulvirenti, Antonio Pecoraro, Alessandra Vultaggio, Carolina Marasco, Roberto Ria, Sara Altinier, Nicolò Compagno, Davide Firinu, Mario Plebani, Marco De Carli, Andrea Matucci, Fabrizio Vianello, Angelo Vacca, Giuseppe Spadaro, Isabella Quinti, Isabella Quinti, Carlo Agostini, Carlo Agostini, Cinzia Milito, Francesco Cinetto, Francesco Cinetto   +22 more
doaj   +1 more source

Accurate Prediction and Key Feature Recognition of Immunoglobulin

Applied Sciences, 2021
Immunoglobulin, which is also called an antibody, is a type of serum protein produced by B cells that can specifically bind to the corresponding antigen.
Yuxin Gong, Bo Liao, Dejun Peng, Quan Zou   +3 more
doaj   +1 more source

Diversity of immunoglobulin light chain genes in non-teleost ray-finned fish uncovers IgL subdivision into five ancient isotypes [PDF]

, 2018
The aim of this study was to fill important gaps in the evolutionary history of immunoglobulins by examining the structure and diversity of IgL genes in non-teleost ray-finned fish.
Andreyushkova, Daria A, Baranov, Konstantin O, Chikaev, Nikolai A, Gessner, Jörn, Guselnikov, Sergey V, Kulemzin, Sergey V, Makunin, Alexey I, Mechetina, Ludmila V, Najakshin, Alexander M, Schartl, Manfred, Stöck, Matthias, Taranin, Alexander V, Trifonov, Vladimir A, Warren, Wesley C, Wuertz, Sven   +14 more
core   +5 more sources

Treatment of immunoglobulin-resistant kawasaki disease: a Bayesian network meta-analysis of different regimens

Frontiers in Pediatrics, 2023
BackgroundThis study aimed to gather evidence from clinical trials on the efficacy and safety of the available treatments for intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) in children.MethodsThis work adopted the Newcastle–Ottawa ...
Yan Pan, Qihong Fan, Luoyi Hu
doaj   +1 more source

Immunoglobulin therapy [PDF]

Clinical Medicine, 2016
Immunoglobulin is an expensive blood product of potentially limited supply used in a wide variety of medical conditions, across a number of specialties. Historically, immunoglobulin has been associated with transmission of blood borne infection (eg hepatitis C). Immunoglobulin use needs to be carefully considered, appropriately prescribed and recorded.
Sarah Louise, Johnston, Rob, Hollingsworth   +1 more
openaire   +2 more sources

Kappa Free Light Chains in the Context of Blood Contamination, and Other IgA- and IgM-Related Cerebrospinal Fluid Disease Pattern

Cells, 2021
In this retrospective, monocentric cohort study, we tested if an intrathecal free light chain kappa (FLC-k) synthesis reflects not only an IgG but also IgA and IgM synthesis.
Malte Johannes Hannich, Alexander Dressel, Kathrin Budde, Astrid Petersmann, Matthias Nauck, Marie Süße   +5 more
doaj   +1 more source

Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]

, 2016
Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht, Changjun Yin, Christian Weber, Coleen A. McNamara, Desheng Hu, Gianluca Grassia, Kulkarni U, Li Peng, Michael Beer, Pasquale Maffia, Prasad Srikakulapu, Rudolf A. Manz, Sai Vineela Bontha, Sarajo K. Mohanta   +13 more
core   +1 more source

Effects of using different levels of dietary chitosan on some immune indices and antioxidant defense system in Vannamei shrimp, Litopenaeus vannamei [PDF]

تغذیه آبزیان
Introduction: Aquaculture aims to provide stable environmental conditions for fish to be able to grow and protect it from stress and diseases. To guarantee a sustainable yield of fish species, well-balanced diets should be considered.
Saeed Dayani, Valiallah Jafari, Roghayeh Safari, Seyed Hossein Hoseinifar   +3 more
doaj   +1 more source

Identification of Glycoxidative Lesion in Isolated Low-Density Lipoproteins from Diabetes Mellitus Subjects

Life, 2023
Methylglyoxal (MG) is a precursor for advanced glycation end-products (AGEs), which have a significant role in diabetes. The present study is designed to probe the immunological response of native and glycated low-density lipoprotein (LDL) in ...
Amjad R. Alyahyawi, Mohd Yasir Khan, Sultan Alouffi, Farah Maarfi, Rihab Akasha, Saif Khan, Zeeshan Rafi, Talal Alharazi, Uzma Shahab, Saheem Ahmad   +9 more
doaj   +1 more source