Results 41 to 50 of about 22,121,106 (346)
Intersection of Coeliac Disease and Sjogren’s Syndrome: A Report of Two Cases [PDF]
Journal of Clinical and Diagnostic ResearchCoeliac Disease (CD) and Sjogren’s Syndrome (SS), both autoimmune disorders, are gaining attention for their complex interaction when occurring together.
Ravi Talapa +3 more
doaj +1 more source
Gut Microbes, 2021 Secretory immunoglobulin A (IgA) interacts with intestinal microbiota and promotes mucosal homeostasis. IgA-bacteria interactions are altered during inflammatory diseases, but how these interactions are shaped by bacterial, host, and environmental ...
Kelsey E Huus +9 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The effect of basketball competition on resting level of Immunoglobulins in elite female basketball players [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2010 This research aimed to investigate the effect of one period of first division basketball competitionon some immune system factors in elite female basketball players.
محمد فرامرزی +2 more
doaj +1 more source
Clinical Immunology Communications, 2023 : Objectives: Elderly become more susceptible to lower respiratory tract infections, resulting in antibiotic prescriptions. Immunoglobulins (Ig) play an important role in host defense and protection against infections. Therefore, we aimed to investigate
Anna Vanoverschelde +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Adverse Effects of Immunoglobulin Therapy
Frontiers in Immunology, 2018 Immunoglobulin has been widely used in a variety of diseases, including primary and secondary immunodeficiency diseases, neuromuscular diseases, and Kawasaki disease.
Yi Guo +3 more
semanticscholar +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma
Nature Communications, 2015 Multiple myeloma (MM) is characterized by an uninhibited, clonal growth of plasma cells. While first-degree relatives of patients with MM show an increased risk of MM, the genetic basis of inherited MM susceptibility is incompletely understood.
Bhairavi Swaminathan +33 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source