Results 111 to 120 of about 113,982,624 (231)
MedComm, Volume 7, Issue 9, September 2026.Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan +9 more
wiley +1 more source
, 1999 We evaluated blood concentrations of bcl-2, a proto-oncogene that can inhibit apoptotic phenomena, in a group of patients with immunoglobulin A (IgA) nephropathy.
ROMEO A +8 more
core +1 more source
Advances in FGF/FGFR Signaling: Implications for Disease and Therapy
MedComm, Volume 7, Issue 9, September 2026.The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song +4 more
wiley +1 more source
Sibeprenlimab (Voyxact) for Primary Immunoglobulin A Nephropathy
Sibeprenlimab (Voyxact – Otsuka), a subcutaneously injected cytokine A proliferation-inducing ligand (APRIL) blocker, has been granted accelerated approval by the FDA to reduce proteinuria in adults with primary immunoglobulin A nephropathy (IgAN; also ...
core +1 more source
Amino Acid Metabolism in Health and Disease
MedComm, Volume 7, Issue 9, September 2026.This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su +7 more
wiley +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.This study describes the first reported case of concurrent sitosterolemia (STSL) and nephronophthisis (NPHP). Additionally, we provide a systematic review of the clinical and genetic characteristics of Chinese STSL patients, representing the largest comprehensive cohort in China to date.
Dan Ding +4 more
wiley +1 more source
Organ Medicine, Volume 3, Issue 3, Page 139-147, September 2026.Serum galactose‐deficient IgA1 levels at 3 and 6 months predicted recurrent IgA nephropathy after kidney transplantation. Recipients without recurrence showed a rapid decline in galactose‐deficient IgA1 after transplantation. Early identification of recurrence risk provided a potential window for targeted post‐transplant intervention.
Ronghai Deng +10 more
wiley +1 more source
IGA Nephropathy : From Molecules to Men /
, 1999 The author of this volume has studied IgA nephropathy for nearly 25 years, almost as long as primary IgA nephropathy has been recognized as a new disease.
Tomino, Y.
core
A Rare Case of COPA Syndrome: Multisystem Relapse and Fatal Septic Complication
Respirology Case Reports, Volume 14, Issue 9, September 2026.A 45‐year‐old man with a history of recurrent respiratory failure, arthritis and renal dysfunction was diagnosed with COPA syndrome through genetic testing after years of progressive interstitial lung disease and immune‐mediated manifestations. He initially responded to immunosuppressive therapy but relapsed after treatment discontinuation, developing ...
Flavia Castro Velasco Fernandes +7 more
wiley +1 more source
Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice
, 1999 The molecular mechanism(s) of immunoglobulin A (IgA) nephropathy, the most common primary renal glomerular disease worldwide, is unknown. Its pathologic features include hematuria, high levels of circulating IgA-fibronectin (Fn) complexes, and glomerular
Zhang, Zhongjian +5 more
core +1 more source