Results 101 to 110 of about 113,982,624 (231)

Immunosuppression, tonsillectomy and remissions in high-risk IgA-nephropathy

Терапевтический архив
Aim.To evaluate the efficacy of immunosuppressive therapy (IST) and tonsillectomy (TE) in patients with high-risk IgA nephropathy (IgAN). Materials and мethods.
Zinaida Sh. Kochoyan, Alina Z. Lieva, Tatyana O. Galkovskaya, Vladimir A. Dobronravov   +3 more
doaj   +1 more source

S100A1 Promotes MDM2‐Mediated KLF15 Ubiquitination to Regulate ID1‐Driven Tubular Injury in Diabetic Kidney Disease

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
High glucose upregulates S100A1, enhancing MDM2–KLF15 interaction and K48‐linked ubiquitination of KLF15. Degradation of KLF15 relieves ID1 repression, promoting ID1 upregulation, inflammation, fibrosis, tubular injury, and DKD progression. ABSTRACT Diabetic kidney disease (DKD) is the leading cause of end‐stage renal disease globally.
Zhitao Zeng, Jiazhen Shang, Shouyu Chai, Xia Zhang, Xincong Lv, Xiaotian Han, Yifan Xu, Baoze Ma, Zhimei Lv, Rong Wang   +9 more
wiley   +1 more source

Clinicopathological Profile of Immunoglobulin A Nephropathy Patients

Journal of College of Medical Sciences-Nepal
Background Immunoglobulin A nephropathy (IgAN) is the most prevalent glomerulonephritis (GN) in the world. It has variation in presentation among the patients.
Deepak Sharma, Pramod Bhusal, Chunumila Maharjan, Madhav Ghimire   +3 more
doaj   +1 more source

Immunoglobulin A nephropathy [PDF]

Journal of the American Society of Nephrology, 1997
J V, Donadio, J P, Grande
openaire   +2 more sources

Hydrocephalus and Diffuse Alveolar Hemorrhage as the Initial Manifestation of Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many systems, such as the central nervous system (CNS), cardiovascular, musculocutaneous, renal, and respiratory systems, etc. SLE can occur alone or in association with other autoimmune diseases, especially antiphospholipid syndrome (APS).
Ehsan Adib, Narges Gorbanmaleki, Amirreza Eterafi, Sara Jalali Jivan   +3 more
wiley   +1 more source

Sibeprenlimab, which neutralizes A PRoliferation Inducing Ligand (APRIL), as a new approach to treating IgA nephropathy

Introduction Immunoglobulin A (IgA) nephropathy is a common immune-mediated kidney disease leading to high blood pressure and may progress to kidney failure. None of the present treatments are disease-modifying or prolong life.
Doggrell, Sheila A
core   +1 more source

Hepatic-associated immunoglobulin-A nephropathy in a child with liver cirrhosis and portal hypertension

, 2012
Hepatic-associated immunoglobulin A (IgA) nephropathy is a relatively common condition that occurs in adults with liver cirrhosis and portal hypertension. However, it is rare in children.
Omar I Saadah, Jaudah Al-Maghrabi, Sharifa A Alghamdi, Nesreen Almatury   +3 more
core   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

Investigating the genetic effects of metformin-related targets on IgA nephropathy using Mendelian randomization

Renal Failure
The role of metformin and its downstream targets in IgA nephropathy (IgAN) remains unclear. In this study, we used Mendelian randomization to explore potential causal links between genetic proxies of metformin targets, plasma proteins, and the risk of ...
Yan Zhang, Jinyan Lin, Peizhuang Zheng, Xingtao Lin, Daowen Zheng   +4 more
doaj   +1 more source