Results 101 to 110 of about 120,903,364 (211)

Immunosuppression, tonsillectomy and remissions in high-risk IgA-nephropathy

Терапевтический архив
Aim.To evaluate the efficacy of immunosuppressive therapy (IST) and tonsillectomy (TE) in patients with high-risk IgA nephropathy (IgAN). Materials and мethods.
Zinaida Sh. Kochoyan, Alina Z. Lieva, Tatyana O. Galkovskaya, Vladimir A. Dobronravov   +3 more
doaj   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, Volume 104, Issue 10, Page 996-1014, November‐December 2026.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Clinicopathological Profile of Immunoglobulin A Nephropathy Patients

Journal of College of Medical Sciences-Nepal
Background Immunoglobulin A nephropathy (IgAN) is the most prevalent glomerulonephritis (GN) in the world. It has variation in presentation among the patients.
Deepak Sharma, Pramod Bhusal, Chunumila Maharjan, Madhav Ghimire   +3 more
doaj   +1 more source

Association of Neutrophil Percentage‐to‐Albumin Ratio (NPAR) With Pathological Features and Long‐Term Prognosis in Diabetic Kidney Disease: A Cohort Study

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
This graphical abstract summarizes the association between the neutrophil percentage‐to‐albumin ratio (NPAR), renal pathology, and prognosis in biopsy‐confirmed diabetic kidney disease. Higher NPAR was associated with increased renal MPO‐positive neutrophil infiltration, more severe histopathological injury, and poorer renal outcomes.
Yang Li, Hongyu Wang, Wendi He, Yi Fang, Shi Jin, Hong Liu, Jie Li, Nana Song, Xiaoqiang Ding, Yan Dai   +9 more
wiley   +1 more source

Clinicopathological Correlations in Immunoglobulin A Nephropathy (IgAN) According to the Oxford MEST-C Classification: A single-Center Study in Karbala

International Journal of Medical Sciences and Academic Research
Background: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and an important cause of chronic kidney disease and kidney failure.
Douaa Yasss Khudair, , Haider Jabur Kehiosh,   +1 more
doaj   +1 more source

Efficacy of Leflunomide, Telmisartan, and Clopidogrel for Immunoglobulin A Nephropathy: A Randomized Controlled Trial

Chinese Medical Journal, 2016
Background: The efficacy and safety of telmisartan combined with clopidogrel, leflunomide, or both drugs for immunoglobulin A nephropathy (IgAN) are unclear.
Jie Wu, Shu-Wei Duan, Xue-Feng Sun, Wen-Ge Li, Ya-Ping Wang, Wen-Hu Liu, Jian-Rong Zhang, Li-De Lun, Xue-Mei Li, Chun-Hua Zhou, Ji-Jun Li, Shu-Wen Liu, Yuan-Sheng Xie, Guang-Yan Cai, Lu Ma, Wen Huang, Hua Wu, Qiang Jia, Xiang-Mei Chen   +18 more
doaj   +1 more source

Immunoglobulin A nephropathy [PDF]

Journal of the American Society of Nephrology, 1997
J V, Donadio, J P, Grande
openaire   +2 more sources

Effect of Corticosteroids on Clinical Outcomes in Patients with IgA Nephropathy: A Meta-analysis of Randomized Controlled Trials

, 2020
Immunoglobulin A (IgA) nephropathy is a very common primary glomerular disease that could lead to kidney failure. In patients with IgA nephropathy, the effect of corticosteroids remains controversial on clinical outcomes.
Xiangxue Lu
core   +1 more source

Investigating the genetic effects of metformin-related targets on IgA nephropathy using Mendelian randomization

Renal Failure
The role of metformin and its downstream targets in IgA nephropathy (IgAN) remains unclear. In this study, we used Mendelian randomization to explore potential causal links between genetic proxies of metformin targets, plasma proteins, and the risk of ...
Yan Zhang, Jinyan Lin, Peizhuang Zheng, Xingtao Lin, Daowen Zheng   +4 more
doaj   +1 more source

Cancer in IgA nephropathy; a letter to the editor on current findings [PDF]

Journal of Nephropharmacology
Maryam ALem, Mahoor Abedzadeh, Zahra Golestani Hotkani, Parham Mashouf, Neda Kianpour, Leila ALem   +5 more
doaj   +1 more source