Results 91 to 100 of about 120,903,364 (211)

CHAPLE‐Like Enteropathy and Renal Microangiopathy in an Adult Patient With CD46 Deficiency

Journal of Clinical Laboratory Analysis, Volume 40, Issue 21, November 2026.
We report an adult patient with a homozygous CD46 variant presenting with lifelong protein‐losing enteropathy, intestinal lymphangiectasia, and CVID‐like hypogammaglobulinemia mimicking CHAPLE syndrome. Concurrent renal biopsy revealed PLA2R‐negative membranous nephropathy with chronic thrombotic microangiopathy, establishing multi‐organ complement ...
Bircan Erden, Pelin Korkmaz, Halil Yazici, Ahmet Burak Dirim, Fatih Beşışık, Nevzat Kahveci, Zeynep Kilinc, Derya Unal, Osman Ozan Yegit, Tuğba Kalaycı, Özge Hürdoğan, Yasemin Özlük, Melek Büyük, Asli Gelincik, Semra Demir   +14 more
wiley   +1 more source

Diagnostic Dilemma: Immunoglobulin A Nephropathy Concurrent with Systemic Lupus Erythematosus

Annals of Rheumatology and Autoimmunity
Renal involvement is a common feature of systemic lupus erythematosus (SLE), but cases of non-lupus nephritis occurring simultaneously with SLE are rare.
Sudipta Nandi, Sunita Aggarwal, Ranvijay Singh, Pradeep Kumar, Anshul Tomar, Vineeta V. Batra   +5 more
doaj   +1 more source

Hirudin ameliorates immunoglobulin A nephropathy by inhibition of fibrosis and inflammatory response

Renal Failure, 2019
Immunoglobulin A nephropathy (IgAN) is characterized by mesangial IgA and IgG co-deposition. As the clinical course of IgAN is highly variable, a lot of patients will eventually develop to end-stage renal disease (ESRD) within years.
Fei Deng, Jingwei Zhang, Yi Li, Wei Wang, Daqing Hong, Guisen Li, Jing Feng   +6 more
doaj   +1 more source

Development and Analytical Validation of a Smartphone‐Based Quantitative Lateral Flow Immunoassay for Serum Cystatin‐C

Journal of Clinical Laboratory Analysis, Volume 40, Issue 21, November 2026.
We developed a gold nanoparticle‐based lateral flow immunoassay that pairs a fixed‐geometry smartphone reader with an Android application for quantitative serum Cystatin‐C measurement. The 15‐min assay covered 0.32–8.00 mg/L with a 0.15 mg/L detection limit and CVs below 10%.
Ye Lian, Ruiying Zheng, Chenqi Yang, Yueyang Luo, Na Zhang, Guojun Lian, Baoqing Li   +6 more
wiley   +1 more source

An Overlap of Anticoagulant-Related and IgA Nephropathy: A Case Report

Glomerular Diseases
Introduction: Anticoagulant-related nephropathy (ARN) is an increasingly recognized cause of acute kidney injury (AKI), initially associated with warfarin use. Supratherapeutic warfarin levels were implicated in kidney toxicity.
Mercedes Galloway, John J. Sim, Andrew Slater, Christopher Bray, Daniel Bishev, Patrick Walker   +5 more
doaj   +1 more source

Immunoglobulin A Nephropathy. Recurrence After Renal Transplantation

Frontiers in Immunology, 2019
IgA nephropathy (IgAN) is the most common primary glomerular disease worldwide. The disease generally runs an indolent course but may lead to ESRD in 20–30% of patients in 20 years or more after diagnosis.
Gabriella Moroni, Mirco Belingheri, Giulia Frontini, Francesco Tamborini, Piergiorgio Messa, Piergiorgio Messa   +5 more
doaj   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

Primary Erythrocytosis (Polycythaemia) in a Neutered Male Dog Presenting With Right Hindlimb Lameness

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A young dog presented with progressive unilateral hindlimb lameness and marked erythrocytosis. Diagnostic investigations excluded secondary causes and confirmed primary erythrocytosis. Targeted vascular ultrasonography identified a right external iliac venous thrombus as the suspected cause of lameness.
Robyn Belch, Perrine Henry, Marisa Ferreira, Albert Aguilera Padros, Maria Lazaro Munoz, Ben Lloyd‐Bradley, Ingrid Isaac, Efa Llewellyn, Aran Nagendran   +8 more
wiley   +1 more source

Renal Outcome of Immunoglobulin A Nephropathy With Mild Proteinuria [PDF]

, 2003
We determined the natural history of immunoglobulin A nephropathy (IgAN) among patients who presented with mild proteinuria (0.2 to 0.4 g/day), and factors associated with development of adverse clinical events, defined as proteinuria 竕ｧ 1.0g/day, blood ...
Miyazaki, Masanobu, Taguchi, Takashi, Tadokoro, Masato, Kohno, Shigeru, Harada, Takashi, Suyama, Naofumi, Horita, Yoshio, Taura, Kouichi, Ozono, Yoshiyuki   +8 more
core  

Progression of renal allograft histology after renal transplantation in recurrent and nonrecurrent immunoglobulin A nephropathy

, 2008
Little information is available regarding renal histology in cases of chronic allograft dysfunction and graft failure in patients with recurrent immunoglobulin A nephropathy.
임범진, 정현주, 김유선, 김명수, 김순일   +4 more
core   +1 more source