Results 81 to 90 of about 120,903,364 (211)

Translating gut microbiome research into therapies for type 1 diabetes

Experimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok, Max Nieuwdorp, Elena Rampanelli   +2 more
wiley   +1 more source

Use of antibiotics for the treatment of immunoglobulin a nephropathy

, 2019
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. IgA is mainly produced by the gut associated lymphoid tissue (GALT).
Gleeson, James, Monteiro, Renato, Berthelot, Laureline, Mkaddem, Sanae Ben, Chemouny, Jonathan, Lepage, Patricia   +5 more
core   +2 more sources

Evaluation of TGF-β1 and MCP-1 expression and tubulointerstitial fibrosis in children with Henoch-Schönlein purpura nephritis and IgA nephropathy: A clinical correlation

Clinics
OBJECTIVES: Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are two diseases with similar clinical presentations but very different prognoses.
Zhao Shuiai, Shen Huijun, Gu Weizhong, Liu Aimin, Mao Jianhua   +4 more
doaj   +1 more source

Cold‐Inducible RNA‐Binding Protein Alleviates Hypertensive Renal Injury Through the KEAP1‐NRF2 Pathway

Smart Medicine, Volume 5, Issue 6, December 2026.
Cirbp is a key regulatory factor in hypertensive renal injury. The CIRBP‐KEAP1‐NRF2 signaling pathway represents a therapeutic target for Ang II‐induced renal injury and redox imbalance. ABSTRACT Angiotensin II (Ang II) plays crucial roles in renal dysfunction, fibrotic changes, apoptosis, and oxidative stress.
Yue Zhang, Qilin Li, Man Luo, Dongxu Hua, Yanhui Sheng, Lei Wang, Peng Li   +6 more
wiley   +1 more source

Effect of hematuria on the outcome of immunoglobulin A nephropathy with proteinuria [PDF]

, 2016
Background:The relationship between hematuria and histological lesions, the effect of hematuria on response to steroid therapy, and the outcome in patients with immunoglobulin A nephropathy (IgAN) remain undetermined.
Takahito Moriyama, Takashi Takei, Chihiro Iwasaki, Kayu Tanaka, Kosaku Nitta   +4 more
core   +2 more sources

Evolution of Views on Pathogenesis and Treatment of Immunoglobulin A-Nephropathy: What’s New Today?

Архивъ внутренней медицины
Immunoglobulin A nephropathy is the most common immune glomerulopathy in the world. Significant evolution of views on the pathogenesis and treatment of the disease is especially noticeable in recent years due to the emergence of new data on the ...
O. N. Sigitova, E. V. Efremova, A. R. Bogdanova, M. I. Khasanova   +3 more
doaj   +1 more source

Identification of C3d Complement Fragments in Lesional Tissues in ANCA‐Associated Vasculitis

ACR Open Rheumatology, Volume 8, Issue 11, November 2026.
Objective Antineutrophil cytoplasmic antibody–associated vasculitis (AAV) is typically described as “pauci‐immune” due to the absence or weak detection of Igs and complement activation within AAV tissue lesions. However, complement fragments have been recently reported in significant amounts in damaged tissue in AAV, notably in traps formed by ...
Claire Galand, Fei Liu, Katherine A. Vernon, Ravi Vats, Christine Lian, V. Michael Holers, Michael Woodbury, H. Terence Cook, David Cuthbertson, Nader Khalidi, Curry Koening, Carol A. Langford, Carol A. McAlear, Paul A. Monach, Christian Pagnoux, Jason A. Campagna, Stefan Wawersik, Shelia Violette, Peter A. Merkel, for the Vasculitis Clinical Research Consortium   +19 more
wiley   +1 more source

Remission of Immunoglobulin A nephropathy following sequential tonsillectomy and appendectomy: A case report

Journal of International Medical Research
Immunoglobulin A nephropathy is a common glomerular disease associated with mucosal immune dysregulation. We report the case of a young woman diagnosed with biopsy-proven immunoglobulin A nephropathy who achieved sustained clinical remission following ...
Peilan Zheng, Guimei Lin, Xiaoxue Weng, Weijia Xu, Miaohua Qiu, Yu Zhong, Jinge Ouyang, Jiejian Chen   +7 more
doaj   +1 more source

Tubulointerstitial Nephritis With Uveitis Syndrome: A Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT TINU syndrome should be considered in any child presenting with unexplained renal dysfunction and uveitis. Early recognition and a multidisciplinary approach involving nephrology and ophthalmology are essential to prevent irreversible renal and ocular damage.
Abdulelah Alshaiban
wiley   +1 more source

Immunoglobulin A nephropathy [PDF]

Nephrology Dialysis Transplantation, 2001
V, Rajaram, H, Liapis
openaire   +2 more sources