Results 81 to 90 of about 113,982,624 (231)
Evolution of Views on Pathogenesis and Treatment of Immunoglobulin A-Nephropathy: What’s New Today?
Архивъ внутренней медициныImmunoglobulin A nephropathy is the most common immune glomerulopathy in the world. Significant evolution of views on the pathogenesis and treatment of the disease is especially noticeable in recent years due to the emergence of new data on the ...
O. N. Sigitova +3 more
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Journal of International Medical ResearchImmunoglobulin A nephropathy is a common glomerular disease associated with mucosal immune dysregulation. We report the case of a young woman diagnosed with biopsy-proven immunoglobulin A nephropathy who achieved sustained clinical remission following ...
Peilan Zheng +7 more
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Immunoglobulin A nephropathy [PDF]
Nephrology Dialysis Transplantation, 2001 V, Rajaram, H, Liapis
openaire +2 more sources
Experimental Physiology, EarlyView.Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu +7 more
wiley +1 more source
Immunoglobulin A nephropathy diagnosis
, 2018 The defining histological hallmark of immunoglobulin A (IgA) nephropathy is the presence of IgA in the mesangium as the sole or dominant immunoreactant. Light microscopy appearances vary very widely.
Sydney C. W. Tang, Kar Neng Lai
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An Overlap of Anticoagulant-Related and IgA Nephropathy: A Case Report
Glomerular DiseasesIntroduction: Anticoagulant-related nephropathy (ARN) is an increasingly recognized cause of acute kidney injury (AKI), initially associated with warfarin use. Supratherapeutic warfarin levels were implicated in kidney toxicity.
Mercedes Galloway +5 more
doaj +1 more source
Hirudin ameliorates immunoglobulin A nephropathy by inhibition of fibrosis and inflammatory response
Renal Failure, 2019 Immunoglobulin A nephropathy (IgAN) is characterized by mesangial IgA and IgG co-deposition. As the clinical course of IgAN is highly variable, a lot of patients will eventually develop to end-stage renal disease (ESRD) within years.
Fei Deng +6 more
doaj +1 more source
Immunoglobulin A Nephropathy. Recurrence After Renal Transplantation
Frontiers in Immunology, 2019 IgA nephropathy (IgAN) is the most common primary glomerular disease worldwide. The disease generally runs an indolent course but may lead to ESRD in 20–30% of patients in 20 years or more after diagnosis.
Gabriella Moroni +5 more
doaj +1 more source
One day of environment‐induced heat stress causes injury to the murine kidney
Experimental Physiology, EarlyView.Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths +3 more
wiley +1 more source
Translating gut microbiome research into therapies for type 1 diabetes
Experimental Physiology, EarlyView.Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok +2 more
wiley +1 more source