Results 11 to 20 of about 120,903,364 (211)

Immunoglobulin A nephropathy

, 2015
Abstract Immunoglobulin A (IgA) nephropathy is the most common primary glomerulonephritis. It runs a slow and sometimes relentless clinical course with consequent end-stage renal failure in 35–40% of patients 25–30 years after first clinical presentation.
Tang, SCW, Lai, KN
core   +10 more sources

Pathogenic Immunoglobulin A-Producing Cells in Immunoglobulin A Nephropathy [PDF]

Journal of Clinical Medicine
Immunoglobulin A nephropathy (IgAN) is the most prevalent primary glomerular disease worldwide and it remains a leading cause of kidney failure. Clinical manifestations of IgA are exacerbated by infections, and emerging data suggest that aberrant mucosal immune responses are important contributors to the immunopathogenesis of this disease. However, the
Yuko Makita, Heather N. Reich
openaire   +3 more sources

Immunoglobulin a nephropathy complicating pulmonary tuberculosis

Annals of Diagnostic Pathology, 1999
A 31-year-old man who presented with smear- and culture-negative pulmonary tuberculosis had associated macroscopic hematuria, elevation of serum creatinine and immunoglobulin A (IgA) levels, overt proteinuria, and peripheral edema. Renal biopsy revealed focal mesangial proliferation with IgA deposits, and a diagnosis of IgA nephropathy was made.
De Siati L., Paroli M., Ferri C., Muda A. O., Bruno G., Barnaba V.   +5 more
openaire   +4 more sources

Effect of dapagliflozin on proteinuria and the slope of the estimated glomerular filtration rate in patients with immunoglobulin A nephropathy: A multicenter prospective study

Journal of International Medical Research
Objective The sodium–glucose cotransporter-2 inhibitor dapagliflozin reduces proteinuria and slows the decline in estimated glomerular filtration rate in patients with chronic kidney disease.
Takeo Koshida, Hitoshi Suzuki, Maki Murkoashi, Hisatsugu Takahara, Yusuke Suzuki, Tomohito Gohda   +5 more
doaj   +2 more sources

Kartagener syndrome complicated by immunoglobulin A nephropathy

International Medical Case Reports Journal, 2018
Kentaro Oka,1 Taro Sugase,1 Tetsu Akimoto,1,2 Takuya Murakami,1 Izumi Nagayama,1 Miwa Kaneko,1 Maki Asakura,1 Ken Ohara,1 Osamu Saito,1 Daisuke Nagata1 1Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan ...
Oka K, Sugase T, Akimoto T, Murakami T, Nagayama I, Kaneko M, Asakura M, Ohara K, Saito O, Nagata D   +9 more
doaj   +1 more source

Advances in Genetics of Immunoglobulin A Nephropathy

, 2016
Familial aggregation of IgA nephropathy (IgAN) and variation in prevalence among different ethnicities indicate inherited factors contribute to disease pathogenesis. Studies have also shown that IgAN patients also have an inherited defect in O-glycosylation of IgA1.
Zhang, Hong, MAGISTRONI, Riccardo, Gharavi, Ali   +2 more
openaire   +3 more sources

One-Year estimated GFR Slope Independently Predicts Clinical Benefit in Immunoglobulin A Nephropathy

, 2022
 Immunoglobulin A nephropathy (IgAN) is a serious, progressive, immune complex–mediated kidney disease. Being a rare disease, a key challenge for the evaluation of potential new treatments for IgAN is that the progression to end-stage kidney disease ...
Reich, Heather N., Lafayette, Richard A., Barratt, Jonathan, Jonathan Barratt (3387179), Andrew M Stone (18271207), Stone, Andrew M., Richard A Lafayette (11976893), Heather N Reich (8956037)   +7 more
core   +6 more sources

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

A pilot and comparative study between pathological and serological levels of immunoglobulin and complement among three kinds of primary glomerulonephritis

BMC Immunology, 2018
Background Immunoglobulin A nephropathy (IgAN), membranous nephropathy (MN) and minimal-change disease (MCD) are three common types of glomerulonephritis in China.
Jin Dong, Tianhao Peng, Jing Gao, Xingwang Jia, Guangtao Yan, Yong Wang   +5 more
doaj   +1 more source

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus [PDF]

, 2010
BACKGROUND: Diabetic nephropathy is a serious complication of diabetes mellitus and is associated with considerable morbidity and high mortality.
Bell Christopher G, Savage, DA, Savage, David A., Savage, D.A., Bell, CG, Beck, Stephan, Stephan Beck, Maxwell, Alexander P.; id_orcid, Maxwell, Alexander P., Maxwell, A.P., Teschendorff, AE, Beck Stephan, Rakyan, VK, Rakyan, V.K., David A Savage, Teschendorff, Andrew E., Christopher G Bell, Andrew E Teschendorff, Maxwell Alexander P, Alexander P Maxwell, Bell, Christopher G., Rakyan, Vardhman K., Savage David A, Beck, S, Rakyan Vardhman K, Bell, C.G., Beck, S., Maxwell, AP, Teschendorff, A.E., Vardhman K Rakyan, Teschendorff Andrew E   +30 more
core   +2 more sources