Results 21 to 30 of about 113,982,624 (231)

Severity of foot process effacement is associated with proteinuria in patients with IgA nephropathy

Kidney Research and Clinical Practice, 2020
Background : : Proteinuria is a significant risk factor for progression of IgA nephropathy (IgAN) and has a positive correlation with severity of foot process effacement (FPE).
Ji-Hye Lee, Si-Hyong Jang, Nam-Jun Cho, Nam Hun Heo, Hyo-Wook Gil, Eun Young Lee, Jong-Seok Moon, Samel Park   +7 more
doaj   +1 more source

Targeted-release budesonide in immunoglobulin A nephropathy; a mini-review [PDF]

Journal of Nephropharmacology, 2023
Immunoglobulin A nephropathy is the most common kind of primary glomerulonephritis worldwide and one of the main causes of renal failure. Systemic corticosteroid therapy may protect against renal deterioration in IgA nephropathy; however, it is not often
Shiva Toumaj, Shahrzad Alimohammadi, Maryam Ghasemi, Shokouh Shayanpour   +3 more
doaj   +1 more source

The analysis of treatment of Immunoglobulin A-nephropathy [PDF]

Terapevticheskii arkhiv, 2020
Aim. An evaluation of the effectiveness of immunosuppressive therapy (IST) and tonsillectomy (TE) in patients with IgA nephropathy (IgAN). Materials and methods. A retrospective cohort of the study included cases with biopsy proven primary IgAN (n=367, age 3412 years, men 55%). We used demographic and clinical and morphological parameters at the time
Vladimir A. Dobronravov, Zinaida Sh. Kochoyan, Tatyana O. Muzhetskaya, Daria I. Lin   +3 more
openaire   +3 more sources

Beneficial effects of systemic immunoglobulin in experimental membranous nephropathy [PDF]

, 1996
Beneficial effects of systemic immunoglobulin in experimental membranous nephropathy. To test the hypothesis that systemic administration of immunoglobulin might reduce glomerular injury in membranous nephropathy through mechanisms involving inhibition ...
Schulze, Matthias, Young, Bessie A., Nangaku, Masaomi, Alpers, Charles E., Pippin, Jeff, Couser, William G., Richardson, Catherine A., Gordon, Katherine L., Johnson, Richard J.   +8 more
core   +1 more source

Paraneoplastic immunoglobulin A nephropathy and associated focal segmental glomerulosclerosis in asymptomatic low volume B-cell lymphoma – a case report

BMC Nephrology, 2018
Background Paraneoplastic glomerulonephritis is rare in haematological malignancies and tends to manifest as minimal change disease, membranous glomerulonephritis or membranoproliferative glomerulonephritis.
Monica Suet Ying Ng, Leo Francis, Elango Pillai, Andrew John Mallett   +3 more
doaj   +1 more source

Efficacy and safety of adding mizoribine to standard treatment in patients with immunoglobulin A nephropathy: A randomized controlled trial

Kidney Research and Clinical Practice, 2017
Background: Mizoribine (MZR) is an immunosuppressive drug used in Japan for treating patients with lupus nephritis and nephrotic syndrome and has been also reportedly effective in patients with immunoglobulin A (IgA) nephropathy.
Keiji Hirai, Susumu Ookawara, Taisuke Kitano, Haruhisa Miyazawa, Kiyonori Ito, Yuichirou Ueda, Yoshio Kaku, Taro Hoshino, Honami Mori, Izumi Yoshida, Kenji Kubota, Yasuyoshi Yamaji, Tetsuro Takeda, Yoshikazu Nakamura, Kaoru Tabei, Yoshiyuki Morishita   +15 more
doaj   +1 more source

Thickened Perirenal Fat Predicts Poor Renal Outcome in Patients with Immunoglobulin A Nephropathy: A Population-Based Retrospective Cohort Study

Kidney Diseases, 2023
Introduction: Perirenal fat is a pad that fills the retroperitoneal space outside the kidney, which affects kidney function in various ways. However, the association between perirenal fat and IgA nephropathy (IgAN) has not yet been elucidated. This study
Hongtu Hu, Zongwei Zhang, Zikang Liu, Fan Chu, Jialu Ran, Wei Liang   +5 more
doaj   +1 more source

Clinical manifestations of IgA nephropathy combined with thin glomerular basement membrane nephropathy in children

Kidney Research and Clinical Practice, 2013
Background: Immunoglobulin A nephropathy (IgAN) and thin glomerular basement membrane nephropathy (TBMN) are the most common causes of persistent hematuria during childhood.
Young Ju Hwang, Dong Sub Kim, Cheol Woo Ko, Min Hyun Cho, Tae In Park   +4 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

A case report of immunoglobulin M nephropathy manifesting as crescentic glomerulonephritis and nephrotic syndrome in an adult

BMC Nephrology, 2019
Background The nature of immunoglobulin M (IgM) nephropathy has been controversial for a long time, but it is now considered an independent disease like immunoglobulin A nephropathy.
Kyoung Sook Park, Ea Wha Kang, Jeong Hae Kie   +2 more
doaj   +1 more source