Results 71 to 80 of about 613,172 (337)
Immunoglobulin E in erythema nodosum. [PDF]
Archives of Disease in Childhood, 1976 Twenty-two children aged from 3 years 6 months to 12 years with erythema nodosum (EN) were grouped according to aetiology into streptococcal, tuberculous, and those whose aetiology was undetermined. Serum IgE levels were determined in all by the radioimmunosorbent technique. Levels were higher (mean value 991 units/ml) in streptococcal EN than in those
S Benetos +4 more
openaire +3 more sources
Chimerization of antibodies by isolation of rearranged genomic variable regions by the polymerase chain reaction [PDF]
, 1991 We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerization ofAbs.
Kaluzab, Brigitte +4 more
core +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Optimization of the treatment of patients with severe chronic urticaria
Medičnì Perspektivi, 2023 Severe chronic urticaria (SCU) is a common disease that burdens the lives of millions of people, reduces their quality of life, and imposes a significant economic burden not only on the health care system, but also directly on the patient.
Ye.M. Dytiatkovska, N.O. Nedohybchenko
doaj +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Immunoglobulin E, what is it good for? [PDF]
Annals of Allergy, Asthma & Immunology, 2016 Fifty years ago the first report of Immunoglobulin E (IgE) was published, and since then this antibody has revolutionized the diagnosis and management of allergic disease. Kimishige and Teruko Ishizaka, et al, initially described IgE after an extensive investigation of a substance that Coca and Cooke had called “reagin” as early as 1923.1 Little work ...
Mitchell H. Grayson, Brian T. Kelly
openaire +2 more sources
IGHV mutational status of nodal marginal zone lymphoma by NGS reveals distinct pathogenic pathways with different prognostic implications [PDF]
, 2019 The precise B cell of origin and molecular pathogenesis of nodal marginal zone lymphoma (NMZL) remain poorly defined. To date, due to the rarity of NMZL, the vast majority of already-published studies have been conducted on a limited number of samples ...
Amato, Teresa +15 more
core +2 more sources
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Advances in omalizumab treatment for IgE-mediated food allergies
Zhongguo Linchuang YixueThe increasing prevalence of food allergies significantly affects both the physical and mental health of patients, while concurrently imposing a substantial economic burden on a global scale.
Siqi WANG, Ling YE, Meiling JIN
doaj +1 more source
Gülhane Tıp Dergisi, 2023 Aims:This study investigated the usefulness of inflammatory parameters such as eosinophilto-lymphocyte ratio (ELR), eosinophil-to-neutrophil ratio (ENR), and neutrophil-to-lymphocyte ratios (NLR) as markers for the diagnosis of patients with allergic ...
Ali Selçuk, Metin Keren
doaj +1 more source