Results 1 to 10 of about 50 (50)
Crystallization of immunoglobulin Fab fragments specific for DNA.
Journal of Biological Chemistry, 1988 The purification and crystallization of Fab fragments of two mouse monoclonal immunoglobulins specific for different DNA structures are described. In each case, papain digestion of the immunoglobulins produced a mixture of Fab species differing in their isoelectric points.
A, Boodhoo +3 more
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Detection of immunoglobulin A1 protease-induced Fab alpha fragments on dental plaque bacteria [PDF]
Infection and Immunity, 1991 The mechanisms by which immunoglobulin A1 (IgA1) protease activity may enable bacteria to evade the effect of specific secretory IgA (S-IgA) antibodies are not clear. A possibility which has received indirect experimental support is that bacteria, as a consequence of the protease activity, become coated with incompetent Fab alpha fragments instead of ...
T, Ahl, J, Reinholdt
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Structure of an immunoglobulin Fab fragment specific for triple-stranded DNA.
Journal of Biological Chemistry, 1994 Triple-stranded DNA of the form poly(Pyr).poly-(Pur).poly(Pyr) (where Pyr represents a pyrimidine, and Pur represents a purine) has become the subject of intense research because of its potential use in the control of gene expression and in the development of sequence-specific reagents for cleaving DNA.
Mol, Clifford D. +4 more
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Three-Dimensional Structure of the Fab′ Fragment of a Human Immunoglobulin at 2.8-Å Resolution [PDF]
Proceedings of the National Academy of Sciences, 1973 The structure of the Fab′ fragment of a human myeloma immunoglobulin was determined by x-ray crystallographic analysis at 2.8-Å resolution. The Fourier map of the electron density was correlated with the aminoacid sequence to obtain a three-dimensional model. Four globular subunits, which correspond to the homology regions of the light and heavy chains,
R J, Poljak +5 more
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Antigenic polypeptide fragments of a receptor related to the Fab fragment of human immunoglobulin from thymus-derived lymphocytes. [PDF]
Proceedings of the National Academy of Sciences, 1982 Certain thymus-derived lymphocytes of man and other primates express surface components related to the variable region of immunoglobulin heavy chains but lack constant region determinants defining any known immunoglobulin class. To obtain structural information on this molecule that can be used for comparison with known immunoglobulins and other ...
J J, Marchalonis +3 more
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Structure of an immunoglobulin Fab fragment specific for poly(dG).poly(dC).
Journal of Biological Chemistry, 1994 Jel 72 is a murine monoclonal antibody that is highly specific for the right-handed DNA duplex formed by poly(dG).poly(dC). The three-dimensional structure of the antigen-binding fragment (Fab) of Jel 72 has been determined by x-ray crystallographic methods and refined to 2.7-A resolution.
C D, Mol +3 more
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Limited proteolysis of human and rabbit immunoglobulins by snake venoms produces Fab-like fragments.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1992 Rabbit and, to a lesser extent, human immunoglobulins (IgGs) are cleaved by snake venoms. The snake venom proteases active on IgGs release fragments which behave on SDS-PAGE like Fab units similar to those released by the thiol-activated enzymes. However, in contrast to the cysteine proteases, the activity of snake venom proteases on IgGs is not only ...
M T, Assakura, F R, Mandelbaum
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Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1977 Parenteral administration of antiencephalytic gamma-globulin and of the Fab-fragments, extracted from it, to rabbits stimulated the formation of specific antibodies. The maximal blood serum specific antibody level in rabbits reimmunized with Fab-fragments was much lower than that following the reimmunization of rabbits with gamma-globulin.
P S, Barban +3 more
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Low-resolution (4.5 Å) refinement of the immunoglobulin J539 Fab fragment [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 1981 openaire +1 more source
X-Ray Crystallographic Studies of the Fab and Fc Fragments of Human Myeloma Immunoglobulins
Cold Spring Harbor Symposia on Quantitative Biology, 1972 R J, Poljak +5 more
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