Results 91 to 100 of about 22,044 (247)

Differentiation of species in human beta-haemolytic group G streptococci using immunoglobulin Fc fragment receptor. [PDF]

, 1992
Nevio Cimolai, A.C.H. Cheong
openalex   +1 more source

Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer: clinicopathological, genomic, and transcriptomic characterization

The Journal of Pathology, EarlyView.
Abstract Mucinous cystic neoplasms (MCNs) of the pancreas are macroscopic precursors of pancreatic cancer. A similar cystic lesion but lacking the ovarian‐type subepithelial stroma has been recently defined as a simple mucinous cyst (SMC); however, its nature remains unclear. This study aims to define the clinicopathological and molecular profiles of a
Antonio Pea, Michele Bevere, Anastasios Gkountakos, Davide Pasini, Denise Fiorini, Andrea Mafficini, Stela Golovco, Michele Simbolo, Serena Pedron, Concetta Sciammarella, Paola Mattiolo, Aldo Mombello, Manuela Villanova, Carlotta Franzina, Francesca Masetto, Calogero Ciulla, Nicola Sperandio, Kohei Fujikura, Masha S. Ahadi, Jaswinder S. Samra, Amber L. Johns, Joanne Verheij, Martijn W.J. Stommel, Hjalmar van Santvoort, Leonor Schubert Santana, Giuseppe Malleo, Michele Milella, Lodewijk A. A. Brosens, Laura D. Wood, David K. Chang, Riccardo De Robertis, Mirko D'Onofrio, Anthony J. Gill, Roberto Salvia, Vincenzo Corbo, Rita T. Lawlor, Aldo Scarpa, Claudio Luchini   +37 more
wiley   +1 more source

A Kinetic Model of Antigen‐Dependent IgG Oligomerization and Complement Binding

Small Science, EarlyView.
A kinetic model capable of predicting IgG oligomerization, a key step in activating the classical complement pathway (CCP) of the immune system, is presented. The impacts of IgG subclass, concentration, and antigen density are analyzed using advanced biophysical techniques.
Jürgen Strasser, Nikolaus Frischauf, Lukas Schustereder, Andreas Karner, Sieto Bosgra, Aran F. Labrijn, Frank J. Beurskens, Johannes Preiner   +7 more
wiley   +1 more source

Immunoglobulin G3 Antibodies Specific for the 19-Kilodalton Carboxyl-Terminal Fragment ofPlasmodium yoeliiMerozoite Surface Protein 1 Transfer Protection to Mice Deficient in Fc-γRI Receptors [PDF]

, 2000
Peter Vukovic, P. Mark Hogarth, Nadine Barnes, David C. Kaslow, Michael F. Good   +4 more
openalex   +1 more source

Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF‐Trap

Small Structures, EarlyView.
The constant fragment (Fc) of the immunoglobulin G1 (IgG1) subtype is a widely used scaffold for designing advanced therapeutics. Herein, together with the integration of experimental and computational techniques, this study reveals the structural dynamics of the N‐glycan‐bound Fc fragment of IgG1 from VEGF‐Trap, providing a new insight into enhancing ...
Ebru Destan, Engin Turkut, Alper Aldeniz, Jungmin Kang, Takehiko Tosha, Makina Yabashi, Baris Yilmaz, Ahmet Can Timucin, Hiroaki Matsuura, Yoshiaki Kawano, Irfan Cinkaya, Hasan DeMirci   +11 more
wiley   +1 more source

Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair ProcessesSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Environmental enteric dysfunction (EED), a chronic diffuse inflammation of the small intestine, is associated with stunting in children in the developing world.
Jinsheng Yu, M. Isabel Ordiz, Jennifer Stauber, Nurmohammad Shaikh, Indi Trehan, Erica Barnell, Richard D. Head, Ken Maleta, Phillip I. Tarr, Mark J. Manary   +9 more
doaj  

722. Immunoglobulin Fc Fragment Tagging Enhances HBV Ag Specific T Cell Immune Responses in Mice Induced by Recombinant Lentivector Immunization [PDF]

, 2008

openalex   +1 more source

Allergic Reactivity and Memory Occur Independently of Sequential Switching Through IgG1

Allergy, EarlyView.
Sequential switching through IgG1 is not required to produce IgE with sufficient allergen‐binding affinity to cause anaphylaxis against food allergens. Sequential switching through IgG1 does not confer a competitive advantage to become an IgE‐expressing cell.
Joshua F. E. Koenig, Adam K. Wade‐Vallance, Rodrigo Jiménez‐Saiz, Kelly Bruton, Siyon Gadkar, Emily Grydziuszko, Tina D. Walker, Melissa E. Gordon, Amy E. Gillgrass, Justin J. Taylor, Susan Waserman, Manel Jordana   +11 more
wiley   +1 more source

Vaccine‐Induced Anti‐IgE Antibodies Neutralize Free IgE but Fail to Bind and Activate Mast Cell‐Displayed IgE

Allergy, EarlyView.
We investigated the mechanisms by which a previously established VLP‐based anti‐IgE vaccine protects against allergic anaphylaxis. We show that passively administered vaccine‐induced IgGs into allergic mice protects them from anaphylaxis without side effects.
Zahra Gharailoo, Monique Vogel, Paul Engeroff, Martin F. Bachmann   +3 more
wiley   +1 more source

Immunoglobulin Fc fragment tagging allows strong activation of endogenous CD4 T cells to re-shape the tumor milieu and enhance the antitumor effect of lentivector immunization (162.4) [PDF]

, 2012
Yukai He, Hong Yuan, Yibing Peng, Haiyan Xiao, Michael Mi, David H. Munn   +5 more
openalex   +1 more source