Conformation changes and dissociation of Fc fragments of rabbit immunoglobulin G as a function of pH [PDF]
Biochemical Journal, 1969 1. The sedimentation coefficients of rabbit immunoglobulin G, four types of Fc fragments, univalent Fab and bivalent F(ab)2 fragments were measured as a function of pH. 2. In conjunction with molecular-weight determinations by sedimentation equilibrium, and with the behaviour on gel filtration, this enabled the state of association of the Fc fragments ...
S. Utsumi, P. A. Charlwood
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Hierarchical Formation of Disulfide Bonds in the Immunoglobulin Fc Fragment Is Assisted by Protein-disulfide Isomerase [PDF]
Journal of Biological Chemistry, 2004 Antibodies provide an excellent system to study the folding and assembly of all beta-sheet proteins and to elucidate the hierarchy of intra/inter chain disulfide bonds formation during the folding process of multimeric and multidomain proteins. Here, the folding process of the Fc fragment of the heavy chain of the antibody MAK33 was investigated.
F. Vinci +6 more
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Инфекция и иммунитет, 2020 The pathogenesis of poststreptococcal glomerulonephritis (PSGN), a major complication of acute infections caused by group A streptococci (GAS) remains unclear.
L. A. Burova +3 more
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ROLE OF Fc FRAGMENTS IN INHIBITION OF XENOGENIC HYPERACUTE REJECTION BY INTRAVENOUS IMMUNOGLOBULIN
Transplantation, 1996 It has been shown that a high dose administration of human intravenous immunoglobulin G (IVIG) prolonged the survival time of xenografted guinea pig heart in the rat. In this study, we compared the effectiveness of intact IVIG (I-IVIG), Fc fragments of IVIG (Fc-IVIG), and F(ab') fragments of IVIG (Fab-IVIG) in preventing xenogenic hyperacute rejection ...
Itsuo Yokoyama +3 more
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13C NMR study of the mode of interaction in solution of the B fragment of staphylococcal protein A and the Fc fragments of mouse immunoglobulin G [PDF]
FEBS Letters, 1993 The mode of interaction of the B domain (FB) of staphylococcal protein A and the Fc fragments of mouse immunoglobulin G (IgG) has been investigated by 13C NMR spectroscopy. Mouse IgG1, IgG2a, and IgG2b proteins have been selectively labeled with 13C at the carbonyl carbon of His, Met, Trp or Tyr residue and used to prepare the corresponding Fc ...
Hiroaki Gouda +5 more
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Immunoglobulin G Fc Fragment‐Binding Proteins in Mycoplasma salivarium Cells [PDF]
Microbiology and Immunology, 1992 AbstractCell proteins of Mycoplasma salivarium were separated by sodium dodecyl sulfate‐polyacrylamide gel electrophoresis, transferred to membranes, then examined for reactivity with human IgG molecules, the Fc fragment of human IgG, and concanavalin A (ConA). Multiple protein bands bound IgG, and most of them also bound ConA.
Yoshihiko Sawa +2 more
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The enhancement of the human immunoglobulin G Fc fragment-binding activity ofMycoplasma salivariumcells by trypsin treatment is ascribed to the binding of trypsin to the Fc fragment [PDF]
FEMS Microbiology Letters, 1995 Human immunoglobulin G Fc fragment-binding activity of Mycoplasma salivarium cells was remarkably enhanced by trypsin treatment of the cells. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis profile of proteins of the cells treated with trypsin was the same as that of the cells treated with pronase, although pronase treatment had been shown to
Yoshihiko Sawa +2 more
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Bacterial Proteins and Their Proposed Interactions with Fc or Fab Fragments of Immunoglobulins
Biochemistry & Physiology: Open Access, 2014 The reactivity of Immunoglobulin Binding Proteins (IBP) to Fc and/or Fab fragments of immunoglobulins was summarized in this review. Staphylococcal protein A (SpA), Streptococcal protein G and Peptostreptococcal protein L (SpL) were the IBP reported. SpA reacted with IgG from skunk, coyote, raccoon, mule and donkey.
Sehlule Vuma +2 more
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In vivo secretion of the mouse immunoglobulin G Fc fragment from rat submandibular glands [PDF]
The Journal of Gene Medicine, 2009 AbstractBackgroundSalivary glands have been proposed as target organs for gene therapy. They secrete endogenous, as well as transgenic proteins, in a polarized manner. Transgene‐encoded regulated pathway proteins primarily follow the regulated pathway in rat salivary glands and are secreted into saliva in an exocrine manner.
Gabor Z. Racz +5 more
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Effect of IgG fragments in IVIG(pH4)on phagocytosis of sensitized erythrocytes by macrophage
Zhongguo shuxue zazhi, 2022 Objective To research the effect of the Fc, Fab and F(ab′)2 fragments of immunoglobulin G, the main components of Human Immunoglobulin(pH4) for Intravenous Injection(IVIG), on the phagocytic function of macrophages derived from THP-1 cells. Methods First
Liyuan ZHU +6 more
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