Reversible Dissociation of Fragment Fc of Rabbit γG-Immunoglobulin
Journal of Biological Chemistry, 1966 Abstract Crystallized Fragment Fc of rabbit γG-globulin, prepared by digestion with papain in the presence of 0.05 m l-cysteine, dissociates into half-fragments in 0.05 m NaCl at pH 2.7. Dissociation is approximately half-complete at pH 3.1. The conditions are similar to those required for dissociation of γG-globulin into half-molecules, which supports
F. P. Inman, Alfred Nisonoff
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Altered IgG N-Glycosylation at Onset of Type 1 Diabetes in Children Is Predominantly Driven by Changes in the Fab N-Glycans [PDF]
BiomedicinesBackground: N-glycosylation is a post-translational modification involving the attachment of oligosaccharides to proteins and is known to influence immunoglobulin G (IgG) effector functions and even antigen binding.
Branimir Plavša +3 more
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Role of Fc fragments in inhibition of xenogenic hyperacute rejection by intravenous immunoglobulin.
Transplantation, 1996 It has been shown that a high dose administration of human intravenous immunoglobulin G (IVIG) prolonged the survival time of xenografted guinea pig heart in the rat. In this study, we compared the effectiveness of intact IVIG (I-IVIG), Fc fragments of IVIG (Fc-IVIG), and F(ab') fragments of IVIG (Fab-IVIG) in preventing xenogenic hyperacute rejection ...
T. Kojima +3 more
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Structure analysis of goose immunoglobulin Y Fc fragment [PDF]
Central European Journal of Immunology, 2013 Objective: Goose immunoglobulin Y (IgY)-Fc fragment gene is cloned. Material and methods: In order to obtain a certain length (106 bp) of constant domain gene, a pair of primer was designed according to the conserved nucleotide sequence of duck (CAA46322) and chick en (S00390) IgY-Fc fragment that was published by the GenBank.
Lei Jiang +4 more
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Customized extracellular vesicles targeting lysosomal biogenesis deliver therapeutic cargo for intervertebral disc degeneration treatment [PDF]
Journal of NanobiotechnologyExtracellular vesicles (EVs) have gained prominence as advanced drug delivery systems due to their inherent merits. Recent advancements highlight their utility in transporting therapeutic proteins with significant progress in targeted therapies.
Zhiwei Liao +4 more
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Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties [PDF]
Protein engineering, design & selection : PEDS, 2010 Gordana Wozniak‐Knopp +12 more
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13C NMR study of the mode of interaction in solution of the B fragment of staphylococcal protein A and the Fc fragments of mouse immunoglobulin G [PDF]
FEBS Letters, 1993 Koichi Kato +5 more
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The Amino Acid Sequence of the Fc Fragment of Rabbit Immunoglobulin G
Journal of Biological Chemistry, 1968 Robert Delaney, Robert L. Hill
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Bacterial Proteins and Their Proposed Interactions with Fc or Fab Fragments of Immunoglobulins
Biochemistry & Physiology: Open Access, 2014 The reactivity of Immunoglobulin Binding Proteins (IBP) to Fc and/or Fab fragments of immunoglobulins was summarized in this review. Staphylococcal protein A (SpA), Streptococcal protein G and Peptostreptococcal protein L (SpL) were the IBP reported. SpA reacted with IgG from skunk, coyote, raccoon, mule and donkey.
Angel A. Justiz Vaillant
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A comparative study of the in vitro immunomodulatory activity of human intact immunoglobulin (7S IVIG), F(ab′)2 fragments (5S IVIG) and Fc fragments. Evidence for post‐transcriptional IL‐2 modulation [PDF]
Immunology, 1997 David Nachbaur +8 more
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