Results 41 to 50 of about 24,903 (156)

INTERACTION BETWEEN DIFFERENT MOLECULAR FORMS OF IMMUNOGLOBULIN A AND RECOMBINANT DERIVATIVES POLYPEPTIDES OF BAC RECEPTOR PROTEINS FROM GROUP B STREPTOCOCCI

Медицинская иммунология, 2014
. The article concerns interactions between immunoglobulin A and recombinant P6, P7, P8 polypeptides, designed on the basis of externally localized Bac protein of the Group B streptococci, possessing IgA-binding activity.There is a current demand for ...
A. S. Korzhueva, D. G. Ibragimova, I. A. Ustinovich, Artem A. Totolian, M. P. Samoilovich, A. N. Suvorov   +5 more
doaj   +1 more source

TFPI-2 Protects Against Gram-Negative Bacterial Infection

Frontiers in Immunology, 2018
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix.
Mohamad N. Ali, Mohamad N. Ali, Gopinath Kasetty, Malin Elvén, Saud Alyafei, Sandra Jovic, Arne Egesten, Heiko Herwald, Artur Schmidtchen, Artur Schmidtchen, Artur Schmidtchen, Praveen Papareddy, Praveen Papareddy   +12 more
doaj   +1 more source

Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair ProcessesSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Environmental enteric dysfunction (EED), a chronic diffuse inflammation of the small intestine, is associated with stunting in children in the developing world.
Jinsheng Yu, M. Isabel Ordiz, Jennifer Stauber, Nurmohammad Shaikh, Indi Trehan, Erica Barnell, Richard D. Head, Ken Maleta, Phillip I. Tarr, Mark J. Manary   +9 more
doaj   +1 more source

Allosteric inhibition of IgE–FcεRI interactions by simultaneous targeting of IgE F(ab’)2 epitopes

Communications Biology
Immunoglobulin E (IgE) plays pivotal roles in allergic diseases through interaction with a high-affinity receptor (FcεRI). We established that Fab fragments of anti-IgE antibodies (HMK-12 Fab) rapidly dissociate preformed IgE-FcεRI complexes in a ...
Takao Hirano, Akemi Koyanagi, Hideo Ago, Masaki Yamamoto, Jiro Kitaura, Masataka Kasai, Ko Okumura   +6 more
doaj   +1 more source

Biochemical and structural characterization of the human gut microbiome metallopeptidase IgAse provides insight into its unique specificity for the Fab' region of IgA1 and IgA2.

PLoS Pathogens
Human immunoglobulin A (IgA), comprising the isotypes IgA1 and IgA2, protects ~400 m2 of mucosal surfaces against microbial infections but can also lead to aberrant IgA deposits that cause disease. Certain bacteria have evolved peptidases that cleave the
Juan Sebastián Ramírez-Larrota, Pauline Juyoux, Pablo Guerra, Ulrich Eckhard, F Xavier Gomis-Rüth   +4 more
doaj   +1 more source

One-step cleavage and purification: a bifunctional IdeS-Protein A fusion protein for on-column generation of antibody fragments. [PDF]

MAbs
Zhang T, Liao H, Teng CB, Wang C.
europepmc   +1 more source

The Promise of Single-Domain Antibodies as Ocular Therapeutics: A Narrative Review. [PDF]

Int J Mol Sci
Jakobsen TS, Kaptain K, Pedersen K, Adsersen RL, Aagaard L, Askou AL, Corydon TJ.   +6 more
europepmc   +1 more source

Fab-Fc and Fab-Fab interactions of variable strength and valency contribute to the high concentration viscosity of IgG₁ antibodies. [PDF]

Proc Natl Acad Sci U S A
Heisler J, Hofmann JL, Tan Z, Zarzar J, Izadi S, Carter PJ.   +5 more
europepmc   +1 more source

Nomenclature of therapies in inflammatory bowel disease: A journey through time and terminology. [PDF]

Inflamm Bowel Dis
Colwill M, Patel K, Sebastian S, Din S, Honap S.   +4 more
europepmc   +1 more source

Complete and Rapid NMR Characterization of Therapeutic Monoclonal Antibodies via Differential Labeling of Fab Fragments in <i>Escherichia coli</i>. [PDF]

Anal Chem
Gagné D, Aubin Y.
europepmc   +1 more source