Results 51 to 60 of about 51,044 (202)

Intravenous Immunoglobulin Protects Against Severe Pandemic Influenza Infection

EBioMedicine, 2017
Influenza is a highly contagious, acute, febrile respiratory infection that can have fatal consequences particularly in individuals with chronic illnesses.
Steven Rockman, Sue Lowther, Sarina Camuglia, Kirsten Vandenberg, Shirley Taylor, Lou Fabri, Sylvia Miescher, Martin Pearse, Deborah Middleton, Stephen J. Kent, Darryl Maher   +10 more
doaj   +1 more source

Regulation of elastase and plasminogen activator secretion in resident and inflammatory macrophages by receptors for the Fc domain of immunoglobulin G. [PDF]

, 1984
We have determined that the interaction of IgG-coated erythrocytes (EIgG) and complement-coated erythrocytes (EIgMC) with macrophage Fc and complement receptors, respectively, modulates the secretion of the neutral proteinases, elastase, and plasminogen ...
Takemura, R, Werb, Z
core  

Diversity of immunoglobulin light chain genes in non-teleost ray-finned fish uncovers IgL subdivision into five ancient isotypes [PDF]

, 2018
The aim of this study was to fill important gaps in the evolutionary history of immunoglobulins by examining the structure and diversity of IgL genes in non-teleost ray-finned fish.
Andreyushkova, Daria A, Baranov, Konstantin O, Chikaev, Nikolai A, Gessner, Jörn, Guselnikov, Sergey V, Kulemzin, Sergey V, Makunin, Alexey I, Mechetina, Ludmila V, Najakshin, Alexander M, Schartl, Manfred, Stöck, Matthias, Taranin, Alexander V, Trifonov, Vladimir A, Warren, Wesley C, Wuertz, Sven   +14 more
core   +5 more sources

Gamma-globulin Inhibits Superantigen-induced Lymphocyte Proliferation and Cytokine Production

Allergology International, 2007
Background: High-dose pooled human immunoglobulin (PHIG) treatment is sometimes effective in superantigen related inflammatory diseases, such as toxic shock syndrome and Kawasaki disease.
Kumiko Kato, Tatsuo Sakamoto, Komei Ito
doaj   +1 more source

Expression, Purification, and Biophysical Characterization of a Secreted Anthrax Decoy Fusion Protein in Nicotiana benthamiana. [PDF]

, 2017
Anthrax toxin receptor-mediated drug development for blocking anthrax toxin action has received much attention in recent decades. In this study, we produced a secreted anthrax decoy fusion protein comprised of a portion of the human capillary ...
Dandekar, Abhaya M, Duhra-Gill, Sifti, Kailemia, Muchena J, Karuppanan, Kalimuthu, Lebrilla, Carlito B, McDonald, Karen A, Nandi, Somen, Phu, My L, Rodriguez, Raymond L   +8 more
core   +2 more sources

Customized extracellular vesicles targeting lysosomal biogenesis deliver therapeutic cargo for intervertebral disc degeneration treatment

Journal of Nanobiotechnology
Extracellular vesicles (EVs) have gained prominence as advanced drug delivery systems due to their inherent merits. Recent advancements highlight their utility in transporting therapeutic proteins with significant progress in targeted therapies.
Zhiwei Liao, Zixuan Ou, Bide Tong, Shuai Li, Cao Yang   +4 more
doaj   +1 more source

Altered IgG N-Glycosylation at Onset of Type 1 Diabetes in Children Is Predominantly Driven by Changes in the Fab N-Glycans

Biomedicines
Background: N-glycosylation is a post-translational modification involving the attachment of oligosaccharides to proteins and is known to influence immunoglobulin G (IgG) effector functions and even antigen binding.
Branimir Plavša, Najda Rudman, Flemming Pociot, Olga Gornik   +3 more
doaj   +1 more source

Staphylococcus pseudintermedius Sbi paralogs inhibit complement and bind IgM, IgG Fc and Fab.

PLoS ONE, 2019
The success of staphylococci as pathogens has been attributed, in part, to their ability to evade their hosts' immune systems. Although the proteins involved in evasion have been extensively studied in staphylococci affecting humans little ...
Alaa H Sewid, M Nabil Hassan, A M Ammar, David A Bemis, Stephen A Kania   +4 more
doaj   +1 more source

Production and characterization of monoclonal antibodies anti fragment Fc of bovine IgG

Brazilian Archives of Biology and Technology, 2010
The aim of this work was to produce and characterize monoclonal antibodies anti bovine immunoglobulin G (IgG). Out of seven hybridomas, two were chosen based on the ELISA'S absorbance values and were labeled B4F11 and B3H12.
Tânia Regina Penha, Ernesto Renato Krüger, Vanete Thomaz-Soccol, Jorge Victor Bacila Agottani, Flávio Hiroshi Itano, Ludmilla Della Coletta Troiano, Josiane Brodzinski   +6 more
doaj   +1 more source

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development [PDF]

, 2017
Acknowledgments: The authors would like to acknowledge the funding support for this work from Scottish Enterprise [VNAR_001(2012)] and the Biotechnology and Biological Sciences Research Council (BB/K010905/1).Peer reviewedPublisher ...
Andrew J. Porter, Andrew J. Porter, Caroline Jane Barelle, Dawn Cornock, Gerard Donohoe, John Steven, Kenneth Saunders, Marina Kovaleva, Miguel F. Carvalho, Mischa R. Müller, Obinna C. Ubah, Thomas Baddeley   +11 more
core   +2 more sources