Conformation changes and dissociation of Fc fragments of rabbit immunoglobulin G as a function of pH [PDF]
Biochemical Journal, 1969 1. The sedimentation coefficients of rabbit immunoglobulin G, four types of Fc fragments, univalent Fab and bivalent F(ab)2 fragments were measured as a function of pH. 2. In conjunction with molecular-weight determinations by sedimentation equilibrium, and with the behaviour on gel filtration, this enabled the state of association of the Fc fragments ...
P. A. Charlwood, S Utsumi
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ROLE OF Fc FRAGMENTS IN INHIBITION OF XENOGENIC HYPERACUTE REJECTION BY INTRAVENOUS IMMUNOGLOBULIN
Transplantation, 1996 It has been shown that a high dose administration of human intravenous immunoglobulin G (IVIG) prolonged the survival time of xenografted guinea pig heart in the rat. In this study, we compared the effectiveness of intact IVIG (I-IVIG), Fc fragments of IVIG (Fc-IVIG), and F(ab') fragments of IVIG (Fab-IVIG) in preventing xenogenic hyperacute rejection ...
Taiki Kojima +3 more
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Immunoglobulin G Fc Fragment‐Binding Proteins in Mycoplasma salivarium Cells [PDF]
Microbiology and Immunology, 1992 AbstractCell proteins of Mycoplasma salivarium were separated by sodium dodecyl sulfate‐polyacrylamide gel electrophoresis, transferred to membranes, then examined for reactivity with human IgG molecules, the Fc fragment of human IgG, and concanavalin A (ConA). Multiple protein bands bound IgG, and most of them also bound ConA.
Yoshihiko Sawa +2 more
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mAbs, 2023 T-cell-engaging bispecific antibodies (T-bsAbs) are promising immunotherapies for cancer treatment due to their capability of redirecting T-cells toward destroying tumor cells.
Han Ping Loh +8 more
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Activating FcγR function depends on endosomal-signaling platforms
iScience, 2023 Summary: Cell surface receptor internalization can either terminate signaling or activate alternative endosomal signaling pathways. We investigated here whether endosomal signaling is involved in the function of the human receptors for Fc immunoglobulin ...
Samira Benadda +8 more
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Improvement of the method of obtaining human IgA Fc-fragments
Regulatory Mechanisms in Biosystems, 2015 To address a number of fundamental and applied problems in immunology, molecular and cellular biology and biotechnology it is necessary to obtain Fc-fragments of immunoglobulins.
O. Y. Galkin +2 more
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The enhancement of the human immunoglobulin G Fc fragment-binding activity ofMycoplasma salivariumcells by trypsin treatment is ascribed to the binding of trypsin to the Fc fragment [PDF]
FEMS Microbiology Letters, 1995 Human immunoglobulin G Fc fragment-binding activity of Mycoplasma salivarium cells was remarkably enhanced by trypsin treatment of the cells. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis profile of proteins of the cells treated with trypsin was the same as that of the cells treated with pronase, although pronase treatment had been shown to
Yoshihiko Sawa +2 more
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Structural insights and biomedical potential of IgNAR scaffolds from sharks [PDF]
, 2014 Peer reviewedPublisher ...
Barelle, Caroline +5 more
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Frontiers in Immunology, 2016 The monospecific and bivalent characteristics of naturally occurring immunoglobulin G (IgG) antibodies depend on homodimerization of the fragment crystallizable (Fc) regions of two identical heavy chains (HCs) and the subsequent assembly of two identical
Ji-Hee Ha, Jung-Eun Kim, Yong-Sung Kim
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Structure of FcRY, an avian immunoglobulin receptor related to mammalian mannose receptors, and its complex with IgY [PDF]
, 2011 Fc receptors transport maternal antibodies across epithelial cell barriers to passively immunize newborns. FcRY, the functional counterpart of mammalian FcRn (a major histocompatibility complex homolog), transfers IgY across the avian yolk sac, and ...
BENNETT +22 more
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