Results 21 to 30 of about 76,339 (318)

Structural insights and biomedical potential of IgNAR scaffolds from sharks [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Barelle, Caroline   +5 more
core   +1 more source

Camelid VHHs Fused to Human Fc Fragments Provide Long Term Protection Against Botulinum Neurotoxin A in Mice

open access: yesToxins, 2019
The bacterium Clostridium botulinum is the causative agent of botulism—a severe intoxication caused by botulinum neurotoxin (BoNT) and characterized by damage to the nervous system. In an effort to develop novel C.
S. A. Godakova   +10 more
semanticscholar   +1 more source

Determination of Physicochemical Properties of Human Immunoglobulin G- Fc Fragment by Bioinformatic [PDF]

open access: yesPars of Jahrom University of Medical Sciences, 2021
Introduction: Immunoglobulins (Igs) are defensive glycoproteins specifically recognize and destroy pathogens. Immunoglobulin G (IgG) is most abundant Ig in serum has important protective role against infections. Fragment of crystallizable (Fc) in IgG has essential role in pathogens destruction.
Soheyla Rohani, Fatemeh Hajighasemi
openaire   +2 more sources

Structure of FcRY, an avian immunoglobulin receptor related to mammalian mannose receptors, and its complex with IgY [PDF]

open access: yes, 2011
Fc receptors transport maternal antibodies across epithelial cell barriers to passively immunize newborns. FcRY, the functional counterpart of mammalian FcRn (a major histocompatibility complex homolog), transfers IgY across the avian yolk sac, and ...
BENNETT   +22 more
core   +3 more sources

Structure analysis of goose immunoglobulin Y Fc fragment

open access: yesCentral European Journal of Immunology, 2013
Objective: Goose immunoglobulin Y (IgY)-Fc fragment gene is cloned. Material and methods: In order to obtain a certain length (106 bp) of constant domain gene, a pair of primer was designed according to the conserved nucleotide sequence of duck (CAA46322) and chick en (S00390) IgY-Fc fragment that was published by the GenBank.
Lei Jiang   +4 more
openaire   +1 more source

Bordetella parapertussis Survives inside Human Macrophages in Lipid Raft-Enriched Phagosomes [PDF]

open access: yes, 2014
Bordetella parapertussis is a human pathogen that causes whooping cough. The increasing incidence of B. parapertussis has been attributed to the lack of cross protection induced by pertussis vaccines. It was previously shown that B. parapertussis is able
Gorgojo, Juan Pablo   +2 more
core   +3 more sources

Single-domain antibodies and their formatting to combat viral infections [PDF]

open access: yes, 2018
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies   +4 more
core   +2 more sources

Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production [PDF]

open access: yes, 2019
Although many recombinant proteins have been produced in seeds at high yields without adverse effects on the plant, endoplasmic reticulum (ER) stress and aberrant localization of endogenous or recombinant proteins have also been reported.
Arcalis, Elsa   +13 more
core   +2 more sources

Enzymic degradation of the Fc fragment of rabbit immunoglobulin IgG [PDF]

open access: yesBiochemical Journal, 1967
The digestion of the Fc fragment of rabbit immunoglobulin IgG by several proteolytic enzymes was investigated by using gel filtration and starch-gel electrophoresis in 8m-urea-formate as criteria of the extent of degradation. Though fragment Fc and mildly reduced fragment Fc proved resistant to tryptic hydrolysis, papain and pepsin cleaved the fragment
openaire   +2 more sources

Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor

open access: yesJournal of Translational Medicine, 2019
Background Neuropsychiatric manifestations are frequent in patients with systemic lupus erythematosus (SLE), yet the etiology and pathogenesis of brain damage in SLE remains unclear.
Chunshu Yang   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy