Results 11 to 20 of about 101,155 (265)
The tumor microenvironment (TME) is a complex structure comprised of tumor, immune and stromal cells, vasculature, and extracellular matrix (ECM). During tumor development, ECM homeostasis is dysregulated. Collagen remodeling by matrix metalloproteinases
Saskia V. Vijver +14 more
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F(ab’)2-Fragments of Antirabic Immunoglobulin Production Using Immobilized Pepsin
Biotechnological scheme for F(ab')2-fragments of anti-rabies immunoglobulin production using immobilized pepsin was developed. Optimal ways for immobilized pepsin production were determined, conditions for fermentative hydrolysis of anti-rabies ...
S. V. Generalov +10 more
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Study of Anaphylactogenic Properties of F(ab')2-Fragments of Heterologous Anti-Rabies Immunoglobulin
Anaphylactogenic properties of heterologous anti-rabies immunoglobulin and its F(ab')2-fragments were tested in vivo. It was shown that F(ab')2-fragments of heterologous anti-rabies immunoglobulin did not possess anaphylactogenic properties.
S.V. Generalov +11 more
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Improvement of the method of obtaining human IgA Fc-fragments
To address a number of fundamental and applied problems in immunology, molecular and cellular biology and biotechnology it is necessary to obtain Fc-fragments of immunoglobulins.
O. Y. Galkin +2 more
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Chronic lymphocytic leukaemia (CLL) is a haematological malignancy for which reliable prognostic markers are needed in view of its clinical heterogeneity.
Beatriz Jatobá Pimentel +4 more
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Presented are the data of analysis of molecular parameters of heterologous immunoglobulin produced by the Russian Research Anti-Plague Institute "Microbe".
E. G. Abramova +7 more
doaj +1 more source
FDG PET/CT in the detection of infections and inflammations [PDF]
Detection of inflammation/infection still remains great clinical problem. That is why nuclear medicine procedures still play a significant role regarding this issue.
Artiko Vera
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Cell-Free Synthesis Meets Antibody Production: A Review
Engineered antibodies are key players in therapy, diagnostics and research. In addition to full size immunoglobulin gamma (IgG) molecules, smaller formats of recombinant antibodies, such as single-chain variable fragments (scFv) and antigen binding ...
Marlitt Stech, Stefan Kubick
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Advancing Luciferase-Based Antibody Immunoassays to Next-Generation Mix and Read Testing
Antibody measurements play a central role in the diagnosis of many autoimmune and infectious diseases. One antibody detection technology, Luciferase Immunoprecipitation Systems (LIPS), utilizes genetically encoded recombinant luciferase antigen fusion ...
Peter D. Burbelo +2 more
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Equine Immunoglobulin and Equine Neutralizing F(ab′)2 Protect Mice from West Nile Virus Infection
West Nile virus (WNV) is prevalent in Africa, Europe, the Middle East, West Asia, and North America, and causes epidemic encephalitis. To date, no effective therapy for WNV infection has been developed; therefore, there is urgent need to find an ...
Jiannan Cui +18 more
doaj +1 more source

