Results 11 to 20 of about 158,982 (309)

Collagen Fragments Produced in Cancer Mediate T Cell Suppression Through Leukocyte-Associated Immunoglobulin-Like Receptor 1

Frontiers in Immunology, 2021
The tumor microenvironment (TME) is a complex structure comprised of tumor, immune and stromal cells, vasculature, and extracellular matrix (ECM). During tumor development, ECM homeostasis is dysregulated. Collagen remodeling by matrix metalloproteinases
Saskia V. Vijver, Saskia V. Vijver, Akashdip Singh, Akashdip Singh, Eline T. A. M. Mommers-Elshof, Eline T. A. M. Mommers-Elshof, Jan Meeldijk, Ronald Copeland, Louis Boon, Sol Langermann, Dallas Flies, Linde Meyaard, Linde Meyaard, M. Inês Pascoal Ramos, M. Inês Pascoal Ramos   +14 more
doaj   +1 more source

Chimerization of antibodies by isolation of rearranged genomic variable regions by the polymerase chain reaction [PDF]

, 1991
We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerization ofAbs.
Kaluzab, Brigitte, Schwirzke, Marina, Weidle, Ulrich H., Weiss, Elisabeth H., Weissenhorn, Winfried   +4 more
core   +1 more source

Study of Anaphylactogenic Properties of F(ab')2-Fragments of Heterologous Anti-Rabies Immunoglobulin

Проблемы особо опасных инфекций, 2009
Anaphylactogenic properties of heterologous anti-rabies immunoglobulin and its F(ab')2-fragments were tested in vivo. It was shown that F(ab')2-fragments of heterologous anti-rabies immunoglobulin did not possess anaphylactogenic properties.
S.V. Generalov, G.P. Lazarenko, R.A. Svintsov, I.M. Zhulidov, A.G. Selezneva, T.A. Mikheeva, L.N. Minaeva, M.V. Galkina, L.V. Savitskaya, A.K. Nikiforov, E.G. Abramova, Yu.V. Brandzishevskiy   +11 more
doaj   +1 more source

Intra- and Interspecies Analyses of the Carcinoembryonic Antigen (CEA) Gene Family Reveal Independent Evolution in Primates and Rodents [PDF]

, 1989
Various rodent and primate DNAs exhibit a stronger intra- than interspecies cross-hybridization with probes derived from the N-terminal domain exons of human and rat carcinoembryonic antigen (CEA)-like genes.
Rudert, Fritz, Thompson, John A., Zimmermann, Wolfgang   +2 more
core   +1 more source

Improvement of the method of obtaining human IgA Fc-fragments

Regulatory Mechanisms in Biosystems, 2015
To address a number of fundamental and applied problems in immunology, molecular and cellular biology and biotechnology it is necessary to obtain Fc-fragments of immunoglobulins.
O. Y. Galkin, Y. V. Gorshunov, V. F. Solovjova   +2 more
doaj   +1 more source

Localization, analysis and evolution of transposed human immunoglobulin VK genes [PDF]

, 1988
The localization of Vκ gene regions to chromosome 2, on which the κ locus is located, and to other chromosomes is described. The Vκ genes that have been transposed to other chromosomes are called orphons.
Bauer, Bernhard Straubinger, Church, Erika Lötscher, Falkner, Franz-Josef Zimmer, Hans G. Zachau, Holst, Honjo, Jaenichen, Kabat, Karl-Heinz Grzeschik, Klobeck, Lorenz, Lötscher, Lötscher, Lötscher, Malcolm, McBride, Pech, Pech, Pohlenz, Pohlenz, Rita Jaenichen, Straubinger, Straubinger, Thomas Klopstock, Tonegawa   +27 more
core   +1 more source

Genomic Organization, Splice Variants and Expression of CGMl, a CD66-related Member of the Carcinoembryonic Antigen Gene Family [PDF]

, 1993
The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains.
Afar D. E. H., Audette M., Baniyash M., Berling B., Culic O., Elsen P., Felgner P. L., Fiddes J. C., Knapp W., Kolbinger F., Kuroki M., Kuroki M., Kuroki M., Lin S.-H., Lucas K., Margolis R. N., McCuaig K., Nap M., Neumaier M., Ng S. Y., Oikawa S., Oikawa S., Paxton R., Pelegrin A., Raskind W. H., Rojas M., Sambrook J. E., Schwarz K., Shively J. E., Skubitz K. M., Southern P. J., Thompson J. A., Thompson J. A., Turbide C., Tynan K., Watt S. M., Woodgett J. R., Zhou H.   +37 more
core   +11 more sources

Use of V H, D and J H immunoglobulin gene segments in Brazilian patients with chronic lymphocytic leukaemia (CLL)

Genetics and Molecular Biology, 2008
Chronic lymphocytic leukaemia (CLL) is a haematological malignancy for which reliable prognostic markers are needed in view of its clinical heterogeneity.
Beatriz Jatobá Pimentel, Cláudio Gustavo Stefanoff, Aline Santos Moreira, Héctor N. Seuánez, Ilana Renault Zalcberg   +4 more
doaj   +1 more source

Determination of the Molecular Parameters of Heterologous Anti-Rabies Immunoglobulin Using Gel-Filtration

Проблемы особо опасных инфекций, 2010
Presented are the data of analysis of molecular parameters of heterologous immunoglobulin produced by the Russian Research Anti-Plague Institute "Microbe".
E. G. Abramova, A. K. Nikiforov, M. N. Kireev, N. N. Kochkalova, S. V. Generalov, A. G. Selezneva, L. V. Savitskaya, Yu. V. Ivanov   +7 more
doaj   +1 more source

FDG PET/CT in the detection of infections and inflammations [PDF]

Archive of Oncology, 2012
Detection of inflammation/infection still remains great clinical problem. That is why nuclear medicine procedures still play a significant role regarding this issue.
Artiko Vera
doaj   +1 more source