Diversity of immunoglobulin light chain genes in non-teleost ray-finned fish uncovers IgL subdivision into five ancient isotypes [PDF]
, 2018 The aim of this study was to fill important gaps in the evolutionary history of immunoglobulins by examining the structure and diversity of IgL genes in non-teleost ray-finned fish.
Andreyushkova, Daria A +14 more
core +5 more sources
Cell-Free Synthesis Meets Antibody Production: A Review
Antibodies, 2015 Engineered antibodies are key players in therapy, diagnostics and research. In addition to full size immunoglobulin gamma (IgG) molecules, smaller formats of recombinant antibodies, such as single-chain variable fragments (scFv) and antigen binding ...
Marlitt Stech, Stefan Kubick
doaj +1 more source
Review of Immunoinformatic approaches to in-silico B-cell epitope prediction [PDF]
, 2007 In this paper, the current state of in-silico, B-cell epitope prediction is discussed. Recommendations for improving some of the approaches encountered are outlined, along with the presentation of an entirely novel technique, which uses molecular ...
Rick Reitmaier
core +2 more sources
Advancing Luciferase-Based Antibody Immunoassays to Next-Generation Mix and Read Testing
Biosensors, 2023 Antibody measurements play a central role in the diagnosis of many autoimmune and infectious diseases. One antibody detection technology, Luciferase Immunoprecipitation Systems (LIPS), utilizes genetically encoded recombinant luciferase antigen fusion ...
Peter D. Burbelo +2 more
doaj +1 more source
Digestion of Protein in Premature and Term Infants. [PDF]
, 2012 Premature birth rates and premature infant morbidity remain discouragingly high. Improving nourishment for these infants is the key for accelerating their development and decreasing disease risk. Dietary protein is essential for growth and development of
Dallas, David C +3 more
core +2 more sources
Equine Immunoglobulin and Equine Neutralizing F(ab′)2 Protect Mice from West Nile Virus Infection
Viruses, 2016 West Nile virus (WNV) is prevalent in Africa, Europe, the Middle East, West Asia, and North America, and causes epidemic encephalitis. To date, no effective therapy for WNV infection has been developed; therefore, there is urgent need to find an ...
Jiannan Cui +18 more
doaj +1 more source
A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]
, 1994 Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Bahn, Rebecca S. +3 more
core +1 more source
VNARs: An Ancient and Unique Repertoire of Molecules That Deliver Small, Soluble, Stable and High Affinity Binders of Proteins [PDF]
, 2015 Peer reviewedPublisher ...
Clem +4 more
core +3 more sources
Mercaptan-induced fragmentation of a subunit-like proteolytic fragment of immunoglobulin M [PDF]
Biochemical Journal, 1972 Limited papain hydrolysis of immunoglobulin M (IgM) produces a subunit-like proteolytic fragment designated IgMp (Inman & Hazen, 1968). In the presence of mercaptans, IgMp partially dissociated into Fcμ-like and Fabμ fragments. Treatment of residual IgM (that remaining after a papain digestion) with 2mm-mercaptoethylamine resulted in fragmentation ...
G M, Butchko, F P, Inman
openaire +2 more sources
Properties of Heterologous anti-Ebola Immunoglobulin after Long Storage
Биопрепараты: Профилактика, диагностика, лечение, 2020 Ebola outbreak in eastern parts of the Democratic Republic of the Congo in 2018–2020 proved that the virus remains highly hazardous for humans, and the outbreak in West Africa in 2014–2016, which was the largest Ebola outbreak in history, showed that it ...
S. A. Melnikov +15 more
doaj +1 more source