Preferential Usage of Specific Immunoglobulin Heavy Chain Variable Region Genes With Unmutated Profile and Advanced Stage at Presentation Are Common Features in Patients With Chronic Lymphocytic Leukemia From Senegal [PDF]
, 2017 Teresa Amato +17 more
openalex +1 more source
Advanced Science, EarlyView.This study combines the biological structure of octopuses with the “3D structure” of spacer fabrics to fabricate a dual‐interface solar evaporator with adaptive hydrothermal balance. Water adaptation is achieved through the differentiated design of the upper and lower layers, and dynamic hydrothermal balance is realized by dynamically regulating the ...
Ning Niu +10 more
wiley +1 more source
TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
Advanced Science, EarlyView.This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao +12 more
wiley +1 more source
Antibody‐Empowered Nanomedicine for Precise Biomedical Applications
Advanced Science, EarlyView.This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen +7 more
wiley +1 more source
The Immunoglobulin Heavy Chain Locus Control Region Increases Histone Acetylation along Linked c-myc Genes [PDF]
, 1998 Linda Madisen +3 more
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Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
Advanced Science, EarlyView.This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Intracellular dissociation and reassembly of prolyl 4-hydroxylase:the α-subunits associated with the immunoglobulin-heavy-chain binding protein (BiP) allowing reassembly with the β-subunit [PDF]
, 1996 David C. A. John, Neil J. Bulleid
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Scalable Upcycling of Spent Lithium‐Ion Battery Anodic Graphite to Electronic‐Grade Graphene
Advanced Science, EarlyView.Graphite anodes from spent lithium‐ion batteries are upcycled into electronic‐grade graphene nanoplatelets for highly conductive screen printing inks (> 104 S m−1). Screen‐printed micro‐supercapacitors confirm the utility of the upcycled graphene (1.78 mF/cm2 capacitance for > 10 000 cycles). Life cycle assessment and techno‐economic analysis highlight
Janan Hui +8 more
wiley +1 more source
Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas. [PDF]
, 1986 D G Bole +2 more
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Foreign labor, peer‐networking and agricultural efficiency in the Italian dairy sector
Agribusiness, EarlyView.Abstract While the presence of immigrants in the agricultural sector is widely acknowledged, the empirical evidence on its economic consequences is lacking, especially from a microeconomic perspective. Using the Farm Accountancy Data Network panel data for Italian dairy farms in the period 2008–2018, the present study investigates the relationship ...
Federico Antonioli +2 more
wiley +1 more source