Results 141 to 150 of about 64,384 (337)
Autoreactive B cells have a central role in the pathogenesis of rheumatoid arthritis (RA), and recent findings have proposed that anti-citrullinated protein autoantibodies (ACPA) may be directly pathogenic.
Amara, Khaled+17 more
core +1 more source
Achieving modular, selective and homogeneous protein modifications is of utmost importance for the design of next generation biopharmaceuticals; especially in the context of antibody‐drug conjugates (ADCs). Here, we introduce unsaturated phosphine oxides as versatile triple‐reactive reagents, allowing orthogonal chemoselective bioconjugation schemes ...
Christian E. Stieger+5 more
wiley +1 more source
Therapeutic effect of natural products on chicken coccidiosis. Abstract The intestinal tract is the main place for animals to digest food and absorb nutrients, which also serves as the first line of defense against pathogens that invade the internal environment.
Pan Chen+6 more
wiley +1 more source
Evidence for somatic selection of natural autoantibodies. [PDF]
Natural autoantibodies are primarily immunoglobulin M (IgM) antibodies that bind to a variety of self-antigens, including self-IgG. Accounting for a large proportion of the early B cell repertoire, such polyspecific autoantibodies are speculated to ...
Carson, DA+3 more
core
Objective Our objective was to assess the incidence of major adverse cardiovascular events (MACEs) in patients with rheumatoid arthritis (RA) treated with JAK inhibitors (JAKi), tumor necrosis factor inhibitors (TNFi), or biologic disease‐modifying antirheumatic drugs with other modes of action (bDMARD‐OMA) in a multicountry, real‐world population ...
Romain Aymon+28 more
wiley +1 more source
In this study, immunoglobulins from serum of Persian sturgeon (Acipenser persicus) were purified and partially characterized. Immunoglobulins were purified from the pooled sera by a combination of salt precipitation, Ion-exchange chromatography and gel ...
M. Kalbasi1; A. Mostafaei2; J. Majidi3
doaj
BackgroundRichter transformation refers to the progression of an initially slow-growing small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) into an aggressive lymphoma, typically diffuse large B-cell lymphoma (DLBCL) or Hodgkin lymphoma ...
Annaïse J. Jauch+8 more
doaj +1 more source
Organization of immunoglobulin heavy chain genes and allelic deletion model. [PDF]
Tasuku Honjo, Tohru Kataoka
openalex +1 more source
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut+1 more
core +1 more source
ABSTRACT Plasma transferrin (Tf) is the transport protein central to the process of iron recycling and metabolism. Holo‐Tf serves as the body's pool of ferric iron, facilitating transport from tissues such as the intestine, liver, spleen, and finally bone marrow, where iron is incorporated into erythropoiesis.
Shuwei Lu+9 more
wiley +1 more source