Results 141 to 150 of about 14,210 (195)

Association of CSF Kappa-Free Light Chains With Cortical and Periventricular Brain Damage in Multiple Sclerosis. [PDF]

open access: yesNeurology
Damulina A   +14 more
europepmc   +1 more source

Kappa-Chain Deficiency

New England Journal of Medicine, 1976
Since kappa-chain deficiency is an unusual condition, we studied the clinical and laboratory findings in a patient with this deficiency. The patient had cystic fibrosis with concurrent malabsorption, diabetes mellitus and IgA deficiency. The serum levels of IgM and IgG were 0.85 and 7.22 mg per milliliter, respectively.
B J, Zegers   +7 more
openaire   +2 more sources

Monoclonal Antibodies Against Rat Immunoglobulin Kappa Chains

Hybridoma, 1982
Monoclonal antibodies directed against rat kappa light chains have been generated by immunizing SJL/J mice with soluble rat immunoglobulin, followed by fusion of immune spleen cells with the P3-X63-Ag8 myeloma cell line. Monoclonal antibodies from three of these hybridoma cell lines, MAR 18.5, 80.2, and 103.6, have been extensively characterized.
L L, Lanier   +4 more
openaire   +2 more sources

Age-related isomerization of Asp in human immunoglobulin G kappa chain

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020
Isomerization of aspartate (Asp) is a common non-enzymatic posttranslational modification. Isomerized residues accumulate in proteins associated with age-related human disorders such as cataract and are well known to affect protein structure and function. We previously detected d-Asp-containing peptides in human serum.
Seongmin, Ha   +2 more
openaire   +2 more sources

Single light chain subclass (kappa chain) immunoglobulin deposition in glomerulonephritis

Human Pathology, 1985
Renal glomerular disease characterized by the deposition of immunoglobulin light chains or monoclonal immunoglobulins was demonstrated by immunofluorescence microscopy in 11 patients. The most common histopathologic findings were those of mesangiocapillary glomerulonephritis, but considerable variability was observed.
C E, Alpers   +3 more
openaire   +2 more sources

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