Results 81 to 90 of about 765,793 (291)

Generation and physiological roles of linear ubiquitin chains [PDF]

, 2012
Ubiquitination now ranks with phosphorylation as one of the best-studied post-translational modifications of proteins with broad regulatory roles across all of biology.
Iwai Kazuhiro, Walczak, H, Walczak, Henning, Kazuhiro Iwai, Walczak Henning, Đikić, Ivan, Ivan Dikic, Iwai, Kazuhiro, Iwai, K, Dikic, I, Dikic Ivan, Henning Walczak   +11 more
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The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Break the chains : a manifesto for the Break the Chains conference to be held on August 8-10, 2003, University of Oregon, Eugene, OR.

, 2003
A manifesto for the conference that was a collaborative effort between the Break the Chains Collective (Eugene, OR), the Anarchist Prisoner's Legal Aid Network (AKA APLAN, Portland, Or) and the National Anarchist Black Cross Network, stating that the ...
Break the Chains (Organization)
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Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

The kappa/lambda ratio of surface immunoglobulin light chain as a valuable parameter for MRD assessment in CLL with atypical immunophenotype

Scientific Reports
In recent years, the significance of detecting minimal/measurable residual disease (MRD) in chronic lymphocytic leukemia (CLL) has increased due to the availability of highly effective therapeutic agents.
Yu Aruga, Chiaki Ikeda, Hiromichi Matsushita, Shinichi Makita, Suguru Fukuhara, Wataru Munakata, Koji Izutsu, Hirotaka Matsui   +7 more
doaj   +1 more source

Blood serum free light chain concentration vs. Imunofixation results in patients with monoclonal gammapathy

Current Issues in Pharmacy and Medical Sciences, 2012
Monoclonal gammapathies are a group of diseases characterized by proliferation of plasma clone cells that produce a certain type of homogenic immunoglobulin containing heavy chains of a, g, m, d, e class aside a type of light k or l chains.
Maciej Korpysz , Arleta Malecha-Jędraszek, Helena Donica   +2 more
doaj   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source

Phi Beta Kappa Minutes, December 5, 1776-January 6,1781 [PDF]

Ledger of the Phi Beta Kappa minutes of meetings from December 5, 1776-January 6, 1781. These are the earliest meetings of Phi Beta Kappa.
Phi Beta Kappa
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Dual‐Field Synergistic Orientation of Carbon Fibers for High‐Efficiency Thermal Management

Carbon Energy, EarlyView.
The sample fabricated by synergistically combining reversed electric and low magnetic fields, with photocurable PEG/PPG gel serving as the matrix, exhibits excellent machinability and flexibility. Meanwhile, the thermal conductivity enhancement efficiency of this work is 1351%, significantly superior to similar carbon fiber composite materials ...
Zujian Zhao, Kang Xu, Yue Qin, Boren Yang, Kaiyuan Li, Linhong Li, Rongjie Yang, Yandong Wang, Hanxi Chen, Yiwei Zhou, Tao Cai, Cheng‐Te Lin, Kazuhito Nishimura, Maohua Li, Nan Jiang, Jinhong Yu   +15 more
wiley   +1 more source

Immunoglobulin allotypes of rabbit kappa chains: Polymorphism of a control mechanism regulating closely linked duplicated genes? [PDF]

, 1976
The amino acid sequence of the constant (CK) region from the kappa immunoglobulin chains of a b9 rabbit is compared with the CK sequences, taken from the literature, of a b4 rabbit.
Hood, L., Goodfliesh, R., Rodkey, S., Farnsworth, V.   +3 more
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