Results 101 to 110 of about 14,209 (224)
Differences in immunoglobulin light chain species found in urinary exosomes in light chain amyloidosis (Al). [PDF]
Renal involvement is a frequent consequence of plasma cell dyscrasias. The most common entities are light chain amyloidosis, monoclonal immunoglobulin deposition disease and myeloma cast nephropathy.
Marina Ramirez-Alvarado +7 more
doaj +1 more source
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source
Classic features of primary systemic amyloidosis (AL amyloidosis) leading to diagnosis of plasma cell myeloma [PDF]
The diagnosis of primary systemic amyloidosis, also known as AL (amyloid light-chain) amyloidosis, is often delayed owing to its nonspecific manifestations as well as its rarity.
Behrens, Emily +3 more
core
IgG‐Secreting Lymphoplasmacytic Lymphoma Presenting With Massive Kidney Infiltration
ABSTRACT Various factors related to lymphoplasmacytic lymphoma (LPL) can lead to kidney complications; however, LPL‐related kidney complications are not as well‐described as those with multiple myeloma. Here, we report a case of IgG‐secreting LPL presenting with acute kidney injury owing to direct tumor infiltration.
Yuichi Nakamura +9 more
wiley +1 more source
Misdiagnosis of hereditary amyloidosis as AL (Primary) amyloidosis [PDF]
Background: Hereditary, autosomal dominant amyloidosis, caused by mutations in the genes encoding transthyretin, fibrinogen A -chain, lysozyme, or apolipoprotein A-I, is thought to be extremely rare and is not routinely included in the differential ...
Booth, D.R. +7 more
core
Monoclonal gammopathy of undetermined significance : natural course and comorbidities [PDF]
Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder characterized by an overproduction of monoclonal immunoglobulins.
Lindqvist, Ebba K
core +1 more source
Aryl Hydrocarbon Receptor in Health and Disease
Based on the structure and ligands of AhR, this review introduces the AhR‐related signaling pathways and their roles in health and diseases. Agonists and antagonists of AhR as well as new strategies for treatment using the microbial–AhR axis are summarized. A prospect was made for the future use of AhR as a therapeutic target.
Haonan Li +11 more
wiley +1 more source
Evolution of Hematopoietic Cell Transplantation for Immunoglobulin Light Chain Amyloidosis [PDF]
Immunoglobulin light chain amyloidosis is the most common type of systemic amyloidosis. Hematopoietic stem cell transplantation (HCT) is an effective treatment option for AL however due to multi-organ involvement in this disease HCT is feasible in a minority of patients.
Angela Dispenzieri +2 more
openaire +3 more sources
Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics
Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen +20 more
wiley +1 more source

