Results 111 to 120 of about 14,209 (224)
Pulmonary light chain deposition disease: Case series and review of the literature
Pulmonary light chain deposition disease is a rare entity characterized by immunoglobulin deposition within the lung parenchyma with pathologic features distinct from pulmonary amyloidosis.
Tomas V. Gonzalez, MD +3 more
doaj +1 more source
Multiple Myeloma : an update on disease biology and therapy [PDF]
Multiple myeloma is a malignancy of immunoglobulin producing plasma cells. Clinical features include bone pain due to lytic bone lesions or pathological fractures, anemia, symptomatic hypercalcemia, renal insufficiency, recurrent infections and ...
Cook, Rachel J., Dingli, David
core
Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis
Patients with immunoglobulin light chain amyloidosis are at risk for both thrombotic and bleeding complications. While the hemostatic defects have been extensively studied, less is known about thrombotic complications in this disease. This retrospective study examined the frequency of venous thromboembolism in 929 patients with immunoglobulin light ...
David C. Seldin +8 more
openaire +3 more sources
ABSTRACT The analysis of immune cell compartments in cancer patients is crucial to predict treatment efficacy and relapse. We introduce a robust 40‐parameter, 37‐channel spectral cytometry panel designed to profile human lymphoid subsets and CAR‐T cell expansion, with the capability to assess exhaustion status by profiling immune checkpoints and ...
Ondrej Venglar +4 more
wiley +1 more source
Folding of a single domain protein entering the endoplasmic reticulum precedes disulfide formation [PDF]
The relationship between protein synthesis, folding and disulfide formation within the endoplasmic reticulum (ER) is poorly understood. Previous studies have suggested pre-existing disulfide links are absolutely required to allow protein folding and ...
Bulleid, Neil J. +3 more
core +1 more source
Candidate genes of Waldenström’s macroglobulinemia: current evidence and research [PDF]
Waldenström’s macroglobulinemia (WM) is a relatively uncommon, indolent malignancy of immunoglobulin M-producing B cells. The World Health Organization classifies it as a lymphoplasmacytic lymphoma and patients typically present with anemia ...
Bianchi, Giada +5 more
core +1 more source
Senile Systemic Amyloidosis: Clinical Features at Presentation and Outcome [PDF]
Background Cardiac amyloidosis is a fatal disease whose prognosis and treatment rely on identification of the amyloid type. In our aging population transthyretin amyloidosis (ATTRwt) is common and must be differentiated from other amyloid types.
Banypersad, SM +15 more
core +1 more source
Multiple Myeloma and AL Amyloidosis [PDF]
O mieloma múltiplo e a amiloidose de cadeias leves (AL) de imunoglobulina são doenças proliferativas plasmocitárias incuráveis que raramente coexistem. Cerca de 10 a 15% dos doentes com mieloma múltiplo desenvolvem amiloidose AL clinicamente sintomática,
Alcatrão, M +5 more
core
Localized AL amyloidosis: A suicidal neoplasm? [PDF]
Although AL amyloidosis usually is a systemic disease, strictly localized AL deposits are not exceptionally rare. Such case reports form a considerable body of published articles.
Westermark, Per
core +2 more sources

