Results 41 to 50 of about 248,538 (216)
Human Autoantibody Silencing by Immunoglobulin Light Chains [PDF]
The Journal of Experimental Medicine, 2004 Several newly arising human antibodies are polyreactive, but in normal individuals the majority of these potentially autodestructive antibodies are removed from the repertoire by receptor editing or B cell deletion in the bone marrow. To determine what proportion of naturally arising autoantibodies can be silenced by immunoglobulin (Ig) light chain ...
Michel C. Nussenzweig +3 more
openaire +3 more sources
Cutaneous amyloidosis as the first presentation of Waldenstrom macroglobulinemia
Caspian Journal of Internal Medicine, 2020 Background: Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma with elevated serum immunoglobulin M and multi-organ involvement. Primary systemic amyloidosis usually develops due to immunoglobulin light chains depositions in different organs ...
Rana Rafiei +2 more
doaj
European Cardiology Review, 2022 AF is the most common cardiac arrhythmia. There is growing evidence that inflammatory mechanisms play an important role in its pathogenesis; inflammasome activation contributes to the onset and progression of AF.
Akira Matsumori
doaj +1 more source
BIMCV COVID-19+: a large annotated dataset of RX and CT images from COVID-19 patients [PDF]
arXiv, 2020 This paper describes BIMCV COVID-19+, a large dataset from the Valencian Region Medical ImageBank (BIMCV) containing chest X-ray images CXR (CR, DX) and computed tomography (CT) imaging of COVID-19+ patients along with their radiological findings and locations, pathologies, radiological reports (in Spanish), DICOM metadata, Polymerase chain reaction ...
arxiv
PLoS ONE, 2020 Immunoglobulin light chain amyloidosis is the most common form of systemic amyloidosis. AL amyloidosis is caused by a misfolded light chain produced by a clonal population of plasma cells.
Elaine C Chen +9 more
doaj +1 more source
Renal tubular P-glycoprotein expression is reduced in plasma cell disorders
Kidney Research and Clinical Practice, 2019 Background : P-glycoprotein (P-gp) transports many chemicals that vary greatly in their structure and function. It is normally expressed in renal proximal tubular cells. We hypothesized that P-gp expression influences light chain excretion.
Cihan Heybeli +9 more
doaj +1 more source
Simultaneous tubular and glomerular involvement with cryoglobulinemia vasculitis in multiple myeloma
Saudi Journal of Kidney Diseases and Transplantation, 2019 Renal manifestations in myeloma are varied. Tubulopathic light chains cause cast nephropathy or proximal tubulopathy, usually associated with tubulointerstitial nephritis.
Zafirah Zahir +3 more
doaj +1 more source
Collective Light Emission of a Finite Size Atomic Chain [PDF]
EPL 100, 24002 (2012), 2012 Radiative properties of collective electronic states in a one dimensional atomic chain are investigated. Radiative corrections are included with emphasize put on the effect of the chain size through the dependence on both the number of atoms and the lattice constant. The damping rates of collective states are calculated in considering radiative effects
arxiv +1 more source
Producing amyloid fibrils in vitro: A tool for studying AL amyloidosis
Biochemistry and Biophysics Reports, 2023 Amyloid light-chain (AL) amyloidosis is the second most common form of systemic amyloidosis which is characterized by a high level of mortality and no effective treatment to remove fibril deposition.
Daria V. Sizova +7 more
doaj
Immunoglobulin genes and diversity: what we have learned from domestic animals
Journal of Animal Science and Biotechnology, 2012 This review focuses on the diversity of immunoglobulin (Ig) genes and Ig isotypes that are expressed in domestic animals. Four livestock species—cattle, sheep, pigs, and horses—express a full range of Ig heavy chains (IgHs), including μ, δ, γ, ϵ, and α ...
Sun Yi +6 more
doaj +1 more source