Results 61 to 70 of about 3,969,240 (284)

Renal tubular P-glycoprotein expression is reduced in plasma cell disorders

Kidney Research and Clinical Practice, 2019
Background : P-glycoprotein (P-gp) transports many chemicals that vary greatly in their structure and function. It is normally expressed in renal proximal tubular cells. We hypothesized that P-gp expression influences light chain excretion.
Cihan Heybeli, Mehmet Asi Oktan, Hayri Ustun Arda, Serkan Yildiz, Mehtat Unlu, Caner Cavdar, Aykut Sifil, Ali Celik, Sulen Sarioglu, Taner Camsari   +9 more
doaj   +1 more source

The immunoglobulin κ gene families of human and mouse: a cottage industry approach [PDF]

, 2000
Some aspects of the work of our group on the human and mouse immunoglobulin κ genes are reviewed. The human κ locus contains a large duplication: a 600 kb C κ-proximal copy with 40 V κ genes is found in the close vicinity of a 440 kb C κ-distal copy with
Zachau, Hans G.
core   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Immunoglobulin genes and diversity: what we have learned from domestic animals

Journal of Animal Science and Biotechnology, 2012
This review focuses on the diversity of immunoglobulin (Ig) genes and Ig isotypes that are expressed in domestic animals. Four livestock species—cattle, sheep, pigs, and horses—express a full range of Ig heavy chains (IgHs), including μ, δ, γ, ϵ, and α ...
Sun Yi, Liu Zhancai, Ren Liming, Wei Zhiguo, Wang Ping, Li Ning, Zhao Yaofeng   +6 more
doaj   +1 more source

Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis.

PLoS ONE, 2020
Immunoglobulin light chain amyloidosis is the most common form of systemic amyloidosis. AL amyloidosis is caused by a misfolded light chain produced by a clonal population of plasma cells.
Elaine C Chen, Samuel Rubinstein, Cinque Soto, Robin G Bombardi, Samuel B Day, Luke Myers, Alexey Zaytsev, Mahsa Majedi, R Frank Cornell, James E Crowe   +9 more
doaj   +1 more source

Fabrication Routes for Ionic Conducting Fiber Strain Sensors

Advanced Engineering Materials, EarlyView.
Ionic conducting fiber strain sensors (ICFSs) offer compliant, textile‐integrable sensing. Thus far, the commercialization of ICFSs has been constrained by fiber fabrication routes. This review provides a fabrication‐centric analysis of ICFSs correlating processing strategies with material properties and scalability.
Leo John Kershaw, Zhanhong Yang, Anne Ladegaard Skov, Magdalena Skowyra   +3 more
wiley   +1 more source

Simultaneous tubular and glomerular involvement with cryoglobulinemia vasculitis in multiple myeloma

Saudi Journal of Kidney Diseases and Transplantation, 2019
Renal manifestations in myeloma are varied. Tubulopathic light chains cause cast nephropathy or proximal tubulopathy, usually associated with tubulointerstitial nephritis.
Zafirah Zahir, Vinita Agrawal, Asif Sadiq Wani, Narayan Prasad   +3 more
doaj   +1 more source

Fluorescent probes of the orientation of myosin regulatory light chains in relaxed, rigor, and contracting muscle. [PDF]

, 1996
The orientation of the light-chain region of myosin heads in relaxed, rigor, and isometrically contracting fibers from rabbit psoas muscle was studied by fluorescence polarization. Cysteine 108 of chicken gizzard myosin regulatory light chain (cgRLC) was
Shrimpton, C., Kendrick-Jones, J., Irving, M., Sleep, J., John Kendrick-jones, Ling, N., Carolyn Shrimpton, Ling, Nicholas, Malcolm Irvingt, Nicholas Ling, John Sleep   +10 more
core   +1 more source

Data for: Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains

, 2022
Data and analysis scripts for the paper: Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains.  The context of the data files is described in the paper and the material deposited here is intended for ...
Rebecca Sternke-Hoffmann (14195194), Christian Malosse (68920), Paolo Marcatili (6215381), Roland Fenk (14195284), Florian Platten (14195280), Luitgard Nagel-Steger (14195289), Florian Tucholski (14195268), Magalie Duchateau (14195271), Rainer Haas (14195286), Alexander Kai Büll (6517340), Thomas Pauly (14195262), Julia Chamot-Rooke (14195283), Rasmus Krogh Norrild (8636853), Amelie Boquoi (10751090), Mathieu Dupré (14195270), Martial Rey (14195276), Sabine Metzger (14195277), Magnus Haraldson Høie (6235031), Stefan U. Egelhaaf (14195282), Jan Hansen (14195265)   +19 more
core   +1 more source

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova, Anna Chiara Bressi, Marina Galliani, Attilio Marino, Gianni Ciofani, Eduardo Machado‐Charry, Hilda Gomez Bernal, Alessandra Francini, Luca Sebastiani, Francesco Greco   +9 more
wiley   +1 more source