Results 61 to 70 of about 50,405 (295)
Silver nanoparticle-based assay for the detection of immunoglobulin free light chains [PDF]
, 2019 There is a wide spectrum of malignant diseases that are connected with the clonal proliferation of plasma cells, which cause the production of complete immunoglobulins or their fragments (heavy or light immunoglobulin chains).
Anna Lizoń +7 more
core +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Renal tubular P-glycoprotein expression is reduced in plasma cell disorders
Kidney Research and Clinical Practice, 2019 Background : P-glycoprotein (P-gp) transports many chemicals that vary greatly in their structure and function. It is normally expressed in renal proximal tubular cells. We hypothesized that P-gp expression influences light chain excretion.
Cihan Heybeli +9 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos +9 more
wiley +1 more source
European Cardiology Review, 2022 AF is the most common cardiac arrhythmia. There is growing evidence that inflammatory mechanisms play an important role in its pathogenesis; inflammasome activation contributes to the onset and progression of AF.
Akira Matsumori
doaj +1 more source
Correlation of Immunoglobulin Free Light Chains in Risk Stratification for Chronic Obstructive Pulmonary Disease Patients [PDF]
, 2020 INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is characterized by an irreversible, progressive airflow limitation associated with abnormal inflammatory response of lungs. B cells have been suggested to contribute to the ongoing inflammation
Geethanjali, R
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Expression of combinatorial immunoglobulins in macrophages in the tumor microenvironment. [PDF]
PLoS ONE, 2018 Recent evidence indicates the presence of macrophage subpopulations that express the TCRαβ in chronic inflammatory diseases such as tuberculosis and atherosclerosis and in the tumor microenvironment.
Tina Fuchs +11 more
doaj +1 more source
, 2011 Bekanntermaßen haben Patienten mit chronischer Niereninsuffizienz eine erhöhte Morbidität und Mortalität. In der vorliegenden Untersuchung wurde geprüft, ob die Serumkonzentrationen an freien Leichtketten Kappa und Lambda prädiktive Faktoren für das ...
Caspari, Cristina Angelina
core +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source