Results 51 to 60 of about 258,914 (247)
Regulation of B cell fate by chronic activity of the IgE B cell receptor. [PDF]
, 2016 IgE can trigger potent allergic responses, yet the mechanisms regulating IgE production are poorly understood. Here we reveal that IgE+ B cells are constrained by chronic activity of the IgE B cell receptor (BCR).
Allen, Christopher DC +6 more
core +1 more source
In Silico Prediction of Continuous Epitopes on Human immunoglobulin Light Chains [PDF]
Journal of Advanced Biomedical Sciences, 2020 Background & Objective: Immunoglobulins (Igs) have a vital role in body protection against germs. Igs contain heavy and light chains. Ig light chains consist of two isotypes: Kappa and lambda.
Soheyla Rohani, Fatemeh Hajighasemi
doaj
Immunoglobulin Light Chain, Lambda
Definitions, 2020 Immunoglobulin Light Chain Lambda is one of two Ig light chain types. Each Ig molecule is typically composed of two heavy chains and two light chains but Ig lambda light chains contain a variable and a constant region.
semanticscholar +1 more source
Folding of a single domain protein entering the endoplasmic reticulum precedes disulfide formation [PDF]
, 2017 The relationship between protein synthesis, folding and disulfide formation within the endoplasmic reticulum (ER) is poorly understood. Previous studies have suggested pre-existing disulfide links are absolutely required to allow protein folding and ...
Bulleid, Neil J. +3 more
core +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2009 La nefropatía de las gammapatías monoclonales es debida, principalmente, al depósito de cadenas ligeras. Las enfermedades renales paraproteinémicas son lesiones asociadas con depósitos de inmunoglobulinas intactas o fragmentos de inmunoglobulinas ...
Jorge de Jesús Cantillo +2 more
doaj +1 more source
Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]
, 1984 Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW +12 more
core +1 more source
Cutaneous amyloidosis as the first presentation of Waldenstrom macroglobulinemia
Caspian Journal of Internal Medicine, 2020 Background: Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma with elevated serum immunoglobulin M and multi-organ involvement. Primary systemic amyloidosis usually develops due to immunoglobulin light chains depositions in different organs ...
Rana Rafiei +2 more
doaj
Novel Biomarkers of Inflammation for the Management of Diabetes: Immunoglobulin-Free Light Chains
Biomedicines, 2022 Virus infection, inflammation and genetic factors are important factors in the pathogenesis of diabetes mellitus. The nuclear factor-kappa B (NF-κB) is a family of transcription factors that bind the enhancer of the κ light chain gene of B cell ...
Akira Matsumori
doaj +1 more source
VNARs: An Ancient and Unique Repertoire of Molecules That Deliver Small, Soluble, Stable and High Affinity Binders of Proteins [PDF]
, 2015 Peer reviewedPublisher ...
Clem +4 more
core +3 more sources
PLoS ONE, 2020 Immunoglobulin light chain amyloidosis is the most common form of systemic amyloidosis. AL amyloidosis is caused by a misfolded light chain produced by a clonal population of plasma cells.
Elaine C Chen +9 more
doaj +1 more source