Results 211 to 220 of about 326,951 (318)

Fab N-Glycosylation in IgG: Implications in Physiological and Pathological Immune Regulation. [PDF]

Biomolecules
Chen S, Yu F, Huang B, Liang G, Xu J, Lin Y, Xu Q.   +6 more
europepmc   +1 more source

Sequence analysis of immunoglobulin variable region genes that encode autoantibodies expressed by lymphomas of mucosa associated lymphoid tissue

Clinical molecular pathology, 1996
C. Chapman, D. Dunn-Walters, F. Stevenson, T. Hussell, P. Isaacson, J. Spencer   +5 more
semanticscholar   +1 more source

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

Advanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu, Siyuan Chang, Zhaoheng Zhang, Tianqi Kang, Mingde Liu, Yuan Zong, Fei Ni, Yinguang Bao, Ruijie Zhang, Xiaobang Zhang, Jinkun Du, Mingming Xin, Zhaorong Hu, Jie Liu, Zhongfu Ni, Qixin Sun, Yingyin Yao   +16 more
wiley   +1 more source

Annotation of gene loci and analysis of expression diversity in sheep immunoglobulin. [PDF]

Front Immunol
Wu M, Chen F, Tang X, Li J, Zhao H, Zhang Y.   +5 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

IgA expressed by glomerular mesangial cells is involved in the pathogenesis of IgA nephropathy. [PDF]

Front Immunol
Zhang H, Deng Z, Gao Y, Li Q, Zhang L, Wang Y.   +5 more
europepmc   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

Standing Still: A Case of Stiff Person Syndrome and Common Variable Immunodeficiency. [PDF]

Cureus
Khazar V, Escobar S, Kim J, McClain S, Szema AM.   +4 more
europepmc   +1 more source

Stochastic rearrangement of immunoglobulin variable-region genes in chicken B-cell development.

Proceedings of the National Academy of Sciences of the United States of America, 1992
Tania Benatar, L. Tkalec, M. J. H. Ratcliffe   +2 more
semanticscholar   +1 more source

Recombination of heavy and light chains of immunoglobulins. Use of specific variable and constant region probes to monitor reassociation reactions.

, 1979
Robert M. Watt, Edward W. Voss
openalex   +1 more source